Search Results - "Brenner, M B"

Predicting initiation and progression of chronic kidney disease: Developing renal risk scores by Taal, M.W., Brenner, B.M.

“…Epidemiological studies have raised awareness of the problem of undiagnosed chronic kidney disease (CKD) and suggest that early identification and treatment…”
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Renal risk scores: Progress and prospects by Taal, M.W., Brenner, B.M.

“…Worldwide adoption of the Kidney Disease Outcomes Quality Initiative classification for chronic kidney disease (CKD) and widespread use of the estimated…”
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CD1a expression defines an interleukin-12 producing population of human dendritic cells by Cernadas, M, Lu, J, Watts, G, Brenner, M.B

“…Human and murine dendritic cell (DC) subsets are often defined by phenotypic features that predict their functional characteristics. In humans and mice, DC…”
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Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial by Miao, Y, Dobre, D, Lambers Heerspink, H. J, Brenner, B. M, Cooper, M. E, Parving, H-H, Shahinfar, S, Grobbee, D, de Zeeuw, D

“…Aims/hypothesis To assess the effect of an angiotensin receptor blocker (ARB) on serum potassium and the effect of a serum potassium change on renal outcomes…”
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Renal risk and renoprotection among ethnic groups with type 2 diabetic nephropathy: A post hoc analysis of RENAAL by de Zeeuw, D., Ramjit, D., Zhang, Z., Ribeiro, A.B., Kurokawa, K., Lash, J.P., Chan, J., Remuzzi, G., Brenner, B.M., Shahinfar, S.

“…Type 2 diabetes is becoming the leading cause of end-stage renal disease (ESRD) worldwide. Prevalence of ESRD and the antihypertensive response to…”
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‘Hypertension’ and ‘microalbuminuria’: The bell tolls for thee by Forman, J.P., Brenner, B.M.

“…Since the terms ‘hypertension’ and ‘microalbuminuria’ were first defined, data from numerous studies have documented the continuous, rather than dichotomous,…”
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Renoprotective benefits of RAS inhibition: From ACEI to angiotensin II antagonists by Taal, Maarten W., Brenner, Barry M.

“…Renoprotective benefits of RAS inhibition: From ACEI to angiotensin II antagonists. In landmark clinical trials, pharmacological inhibition of the…”
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Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A Meta-Analysis of Patient-Level Data by JAFAR, Tazeen H, SCHMID, Christopher H, BECKER, Gavin, HIMMELMANN, Andres, BANNISTER, Kym, LANDAIS, Paul, SHAHINFAR, Shahnaz, DE JONG, Paul E, DE ZEEUW, Dick, LAU, Joseph, LEVEY, Andrew S, LANDA, Marcia, GIATRAS, Loannis, TOTO, Robert, REMUZZI, Giuseppe, MASCHIO, Giuseppe, BRENNER, Barry M, KAMPER, Annelise, ZUCCHELLI, Pietro

“…To examine the efficacy of ACE inhibitors for treatment of nondiabetic renal disease. 11 randomized, controlled trials comparing the efficacy of…”
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Diverse TCRs recognize murine CD1 by Behar, S M, Podrebarac, T A, Roy, C J, Wang, C R, Brenner, M B

“…Human and murine T cells that specifically recognize CD1d and produce IL-4 and IFN-gamma play a role in immunoregulation and tumor rejection. In the mouse,…”
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CD1-Restricted T Cell Recognition of Microbial Lipoglycan Antigens by Sieling, P. A., Chatterjee, D., Porcelli, S. A., Prigozy, T. I., Mazzaccaro, R. J., Soriano, T., Bloom, B. R., Brenner, M. B., Kronenberg, M., Brennan, P. J., Modlin, R. L.

“…It has long been the paradigm that T cells recognize peptide antigens presented by major histocompatibility complex (MHC) molecules. However, nonpeptide…”
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CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection by Moody, D. Branch, Ulrichs, Timo, Mühlecker, Walter, Young, David C, Gurcha, Sudagar S, Grant, Ethan, Rosat, Jean-Pierre, Brenner, Michael B, Costello, Catherine E, Besra, Gurdyal S, Porcelli, Steven A

“…The discovery of the CD1 antigen presentation pathway has expanded the spectrum of T-cell antigens to include lipids, but the range of natural lipid antigens…”
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Hyperfiltration in remnant nephrons : a potentially adverse response to renal ablation by HOSTETTER, T. H, OLSON, J. L, RENNKE, H. G, VENKATACHALAM, M. A, BRENNER, B. M

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Adverse effects of left ventricular hypertrophy in the reduction of endpoints in NIDDM with the angiotensin II antagonist losartan (RENAAL) study by BONER, G, COOPER, M. E, MCCARROLL, K, BRENNER, B. M, DE ZEEUW, D, KOWEY, P. R, SHAHINFAR, S, DICKSON, T, CROW, R. S, PARVING, H.-H

“…We explored the impact of baseline left ventricular hypertrophy (LVH) and losartan treatment on renal and cardiovascular (CV) events in 1,513 patients from the…”
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Reduced insulin secretion and content in VEGF-a deficient mouse pancreatic islets by Jabs, N, Franklin, I, Brenner, M B, Gromada, J, Ferrara, N, Wollheim, C B, Lammert, E

“…Mice, deficient for vascular endothelial growth factor VEGF-A in pancreatic islets, have reduced insulin gene expression levels and an impaired glucose…”
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Transcriptional regulation of the endothelin-1 gene by TNF-alpha by Marsden, P A, Brenner, B M

“…Cytokines, such as tumor necrosis factor-alpha (TNF-alpha), induce profound alterations in endothelial cell phenotype and are implicated in the organ…”
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Nephron adaptation to renal injury or ablation by Brenner, B M

“…In early stages of permanent renal injury or extensive ablation, structural and functional adaptations associated with hypertrophy partially compensate for…”
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Diverse biological actions of atrial natriuretic peptide by Brenner, B M, Ballermann, B J, Gunning, M E, Zeidel, M L

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Differential Effects of Cytolytic T Cell Subsets on Intracellular Infection by Stenger, Steffen, Mazzaccaro, Richard J., Uyemura, Koichi, Cho, Sungae, Barnes, Peter F., Rosat, Jean-Pierre, Sette, Alessandro, Brenner, Michael B., Porcelli, Steven A., Bloom, Barry R., Modlin, Robert L.

“…In analyzing mechanisms of protection against intracellular infections, a series of human CD1-restricted T cell lines of two distinct phenotypes were derived…”
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Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain by PORCELLI, S, YOCKEY, C. E, BRENNER, M. B, BALK, S. P

“…CD4-CD8- (double negative [DN]) alpha/beta T cells are a largely uncharacterized subpopulation of unknown function. To investigate whether these cells are…”
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Congenital oligonephropathy and the etiology of adult hypertension and progressive renal injury by Brenner, B M, Chertow, G M

“…Based on the associations reviewed in this report, we have hypothesized that retardation of renal development as occurs in individuals of low birth weight…”
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