Search Results - "Brenneman, Jehrod B."
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(+)-Sorangicin A: evolution of a viable synthetic strategy
Published in Tetrahedron (23-12-2011)“…An effective, asymmetric total synthesis of the antibiotic (+)-sorangicin A ( 1) has been achieved. Central to this venture was the development of first- and…”
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Application of Intramolecular Enyne Metathesis to the Synthesis of Aza[4.2.1]bicyclics: Enantiospecific Total Synthesis of (+)-Anatoxin-a
Published in Organic letters (15-04-2004)“…A concise synthesis of the potent nAChR agonist (+)-anatoxin-a (1) has been completed in a series of only nine chemical operations and 27% overall yield from…”
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Application of a domino intramolecular enyne metathesis/cross metathesis reaction to the total synthesis of (+)-8-epi-xanthatin
Published in Organic letters (13-10-2005)“…[reaction: see text] The first total synthesis of the novel sesquiterpene lactone (+)-8-epi-xanthatin (1) has been achieved starting from the commercially…”
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The Novel, Clinical-Stage Soluble Guanylate Cyclase Activator BI 685509 Protects from Disease Progression in Models of Renal Injury and Disease
Published in The Journal of pharmacology and experimental therapeutics (01-03-2023)“…Activation of soluble guanylate cyclase (sGC) to restore cyclic guanosine monophosphate (cGMP) and improve functionality of nitric oxide (NO) pathways impaired…”
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Total Synthesis of (+)-Sorangicin A
Published in Journal of the American Chemical Society (02-09-2009)“…The final synthetic challenges associated with (+)-sorangicin A have been overcome, thus leading to the first total synthesis of this complex macrolide…”
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Domino intramolecular enyne metathesis/cross metathesis approach to the xanthanolides. Enantioselective synthesis of (+)-8- epi-xanthatin
Published in Tetrahedron (04-12-2006)“…The first total synthesis of (+)-8- epi-xanthatin ( 1) has been achieved in 14 steps starting from the commercially available ester 24, which was converted…”
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Enantioselective synthesis of (+)-anatoxin-a via enyne metathesis
Published in Tetrahedron (16-08-2004)“…A concise synthesis of the potent nAChR agonist (+)-anatoxin-a ( 1 ) has been completed by a series of nine chemical operations and in 27% overall yield from…”
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Application of a Domino Intramolecular Enyne Metathesis/Cross Metathesis Reaction to the Total Synthesis of (+)-8-e pi-Xanthatin
Published in Organic letters (13-10-2005)“…The first total synthesis of the novel sesquiterpene lactone (+)-8-epi-xanthatin (1) has been achieved starting from the commercially available ester 8. The…”
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(+)-Sorangicin A: evolution of a viable synthetic strategy: Organic Synthesis-2011: Perspective, Journeys, and Accounts
Published in Tetrahedron (2011)Get full text
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