Search Results - "Brennan‐Speranza, Tara C"

Undercarboxylated Osteocalcin Improves Insulin‐Stimulated Glucose Uptake in Muscles of Corticosterone‐Treated Mice by Lin, Xuzhu, Parker, Lewan, McLennan, Emma, Hayes, Alan, McConell, Glenn, Brennan‐Speranza, Tara C, Levinger, Itamar

“…ABSTRACT Short‐term administration of glucocorticoids (GCs) impairs muscle insulin sensitivity at least in part via the reduction of undercarboxylated…”
Get full text

Undercarboxylated osteocalcin and ibandronate combination ameliorates hindlimb immobilization‐induced muscle wasting by Lin, Xuzhu, Smith, Cassandra, Moreno‐Asso, Alba, Zarekookandeh, Navabeh, Brennan‐Speranza, Tara C., Duque, Gustavo, Hayes, Alan, Levinger, Itamar

“…Immobilization leads to muscle wasting and insulin resistance, particularly during ageing. It has been suggested that undercarboxylated osteocalcin (ucOC)…”
Get full text

Healthy lifestyles are associated with better vitamin D status in community‐dwelling older men: The Health In Men Study (HIMS) by Liu, Xiaoying, Brock, Kaye E., Brennan‐Speranza, Tara C., Flicker, Leon, Golledge, Jonathan, Hankey, Graeme J., Girgis, Christian M., Yeap, Bu B.

“…Objective Older people are more prone to vitamin D deficiency than younger populations. Individual lifestyle factors have been associated with vitamin D…”
Get full text

Higher Undercarboxylated to Total Osteocalcin Ratio Is Associated With Reduced Physical Function and Increased 15‐Year Falls‐Related Hospitalizations: The Perth Longitudinal Study of Aging Women by Smith, Cassandra, Lewis, Joshua R, Sim, Marc, Lim, Wai H, Lim, Ee Mun, Blekkenhorst, Lauren C, Brennan‐Speranza, Tara C, Adams, Leon, Byrnes, Elizabeth, Duque, Gustavo, Levinger, Itamar, Prince, Richard L

“…ABSTRACT Evidence from animal models suggests that undercarboxylated osteocalcin (ucOC) is involved in muscle mass maintenance and strength. In humans, the…”
Get full text

Glucocorticoid‐Induced Insulin Resistance in Men Is Associated With Suppressed Undercarboxylated Osteocalcin by Parker, Lewan, Lin, Xuzhu, Garnham, Andrew, McConell, Glenn, Stepto, Nigel K, Hare, David L, Byrnes, Elizabeth, Ebeling, Peter R, Seeman, Ego, Brennan‐Speranza, Tara C, Levinger, Itamar

“…ABSTRACT In mice, glucocorticoid‐induced insulin resistance occurs largely through impaired osteoblast function and decreased circulating undercarboxylated…”
Get full text

Vitamin D and Skeletal Muscle: Current Concepts From Preclinical Studies by Girgis, Christian M., Brennan‐Speranza, Tara C.

“…ABSTRACT Muscle weakness has been recognized as a hallmark feature of vitamin D deficiency for many years. Until recently, the direct biomolecular effects of…”
Get full text

Glucose‐loading reduces bone remodeling in women and osteoblast function in vitro by Levinger, Itamar, Seeman, Ego, Jerums, George, McConell, Glenn K., Rybchyn, Mark S., Cassar, Samantha, Byrnes, Elizabeth, Selig, Steve, Mason, Rebecca S., Ebeling, Peter R., Brennan‐Speranza, Tara C.

“…Aging is associated with a reduction in osteoblast life span and the volume of bone formed by each basic multicellular unit. Each time bone is resorbed, less…”
Get full text

Microfluidic device with a carbonate‐rich hydroxyapatite micro‐coating by Lui, Florence H. Y., Xu, Liangcheng, Michaux, Pierrette, Biazik, Joanna, Harm, Gregory F. S., Oliver, Rema A., Koshy, Pramod, Walsh, William R., Mobbs, Ralph J., Brennan‐Speranza, Tara C., Wang, Yu, You, Lidan, Sorrell, Charles C.

“…A contiguous carbonate‐rich hydroxyapatite microcoating in a microfluidic device represents a substrate that has chemical and structural similarity to bone…”
Get full text

Undercarboxylated Osteocalcin: Experimental and Human Evidence for a Role in Glucose Homeostasis and Muscle Regulation of Insulin Sensitivity by Lin, Xuzhu, Brennan-Speranza, Tara C, Levinger, Itamar, Yeap, Bu B

“…Recent advances have indicated that osteocalcin, and in particular its undercarboxylated form (ucOC), is not only a nutritional biomarker reflective of vitamin…”
Get full text

A diet high in fat and fructose adversely affects osseointegration of titanium implants in rats by King, Shalinie, Baptiston Tanaka, Carina, Ross, Dean, Kruzic, Jamie J., Levinger, Itamar, Klineberg, Iven, Brennan‐Speranza, Tara C.

“…Objectives Diet‐induced metabolic dysfunction such as type 2 diabetes mellitus increases the risk of implant failure in both dental and orthopaedic settings…”
Get full text

Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats by Lin, Xuzhu, Hanson, Erik, Betik, Andrew C, Brennan‐Speranza, Tara C, Hayes, Alan, Levinger, Itamar

“…ABSTRACT Undercarboxylated osteocalcin (ucOC) has been implicated in skeletal muscle insulin sensitivity and function. However, whether muscle mass and…”
Get full text

Skeletal Muscle and the Maintenance of Vitamin D Status by Rybchyn, Mark S, Abboud, Myriam, Puglisi, David A, Gordon-Thomson, Clare, Brennan-Speranza, Tara C, Mason, Rebecca S, Fraser, David R

“…Vitamin D, unlike the micronutrients, vitamins A, E, and K, is largely obtained not from food, but by the action of solar ultraviolet (UV) light on its…”
Get full text

Sleep duration is associated with vitamin D deficiency in older women living in Macao, China: A pilot cross-sectional study by Liu, Xiaoying, Ke, Liang, Ho, Jacky, Abboud, Myriam, Mpofu, Elias, Brennan-Speranza, Tara C, Mason, Rebecca S, Brock, Kaye E

“…Chinese women are known to have both a high prevalence of metabolic syndrome (MetS) and vitamin D deficiency (serum 25-hydroxyvitamin D (25OHD) <50 nmol/l)…”
Get full text

The effect of hyperglycaemia on osseointegration: a review of animal models of diabetes mellitus and titanium implant placement by King, Shalinie, Klineberg, Iven, Levinger, Itamar, Brennan-Speranza, Tara C.

“…Summary Patients with type 2 diabetes mellitus have a higher risk of dental and/or orthopaedic implant failure. However, the mechanism behind this phenomenon…”
Get full text

Recombinant Uncarboxylated Osteocalcin Per Se Enhances Mouse Skeletal Muscle Glucose Uptake in both Extensor Digitorum Longus and Soleus Muscles by Lin, Xuzhu, Parker, Lewan, Mclennan, Emma, Zhang, Xinmei, Hayes, Alan, McConell, Glenn, Brennan-Speranza, Tara C, Levinger, Itamar

“…Emerging evidence suggests that undercarboxylated osteocalcin (ucOC) improves muscle glucose uptake in rodents. However, whether ucOC can directly increase…”
Get full text

Changes of vitamin D levels and bone turnover markers after CPAP therapy: a randomized sham‐controlled trial by Theorell‐Haglöw, Jenny, Hoyos, Camilla M., Phillips, Craig L., Yee, Brendon J., Herrmann, Markus, Brennan‐Speranza, Tara C., Grunstein, Ronald R., Liu, Peter Y.

“…Summary The aim was to investigate whether continuous positive airway pressure treatment could modulate serum vitamin D (25‐hydroxyvitamin D) and bone turnover…”
Get full text

Distinct Effects of a High Fat Diet on Bone in Skeletally Mature and Developing Male C57BL/6J Mice by Ross, Dean S, Yeh, Tzu-Hsuan, King, Shalinie, Mathers, Julia, Rybchyn, Mark S, Neist, Elysia, Cameron, Melissa, Tacey, Alexander, Girgis, Christian M, Levinger, Itamar, Mason, Rebecca S, Brennan-Speranza, Tara C

“…Increased risks of skeletal fractures are common in patients with impaired glucose handling and type 2 diabetes mellitus (T2DM). The pathogenesis of skeletal…”
Get full text

Relationship between serum osteocalcin/undercarboxylated osteocalcin and type 2 diabetes: a systematic review/meta-analysis study protocol by Liu, Yihui, Liu, Xiaoying, R Lewis, Joshua, Brock, Kaye, C Brennan-Speranza, Tara, Teixeira-Pinto, Armando

“…IntroductionThe global burden of type 2 diabetes (T2DM) is steadily increasing. Experimental studies have demonstrated that a novel hormone secreted by bone…”
Get full text

Effects of ovariectomy on the changes in microarchitecture and material level properties in response to hind leg disuse in female rats by Maïmoun, Laurent, Brennan-Speranza, Tara C, Rizzoli, René, Ammann, Patrick

“…Abstract Background Ovariectomy (OVX) and immobilization are known to decrease bone mineral density and alter its microarchitecture. Their effects on the…”
Get full text

Nutritional intake and bone health by Rizzoli, René, Biver, Emmanuel, Brennan-Speranza, Tara C

“…Osteoporotic or fragility fractures affect one in two women and one in five men who are older than 50. These events are associated with substantial morbidity,…”
Get full text