Search Results - "Brennan, Sinéad"

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial by Mehanna, Hisham, Robinson, Max, Hartley, Andrew, Kong, Anthony, Foran, Bernadette, Fulton-Lieuw, Tessa, Dalby, Matthew, Mistry, Pankaj, Sen, Mehmet, O'Toole, Lorcan, Al Booz, Hoda, Dyker, Karen, Moleron, Rafael, Whitaker, Stephen, Brennan, Sinead, Cook, Audrey, Griffin, Matthew, Aynsley, Eleanor, Rolles, Martin, De Winton, Emma, Chan, Andrew, Srinivasan, Devraj, Nixon, Ioanna, Grumett, Joanne, Leemans, C René, Buter, Jan, Henderson, Julia, Harrington, Kevin, McConkey, Christopher, Gray, Alastair, Dunn, Janet, Moleron, Rafael, McArdle, Orla, Dyker, Karen, Al Booz, Hoda, O'Toole, Lorcan, Cook, Audrey, Husband, David, Loo, Vivienne, Soe, Win, Aynsley, Eleanor, Sridhar, Thiagarajan, Jankowska, Petra, Joseph, Mano, Geropantas, Konstantinos, Vaidya, Deepali, Griffin, Matthew, Hartley, Andrew, Vijayan, Rengarajan, Hwang, David, Harrington, Kevin, Pettit, Laura, Whitaker, Stephen, De Winton, Emma, Rolles, Martin, Brennan, Sinéad, Sen, Mehmet, Mendes, Ruheena, Forster, Martin, Chan, Andrew, Evans, Mererid, Buter, Jan, Srinivasan, Devraj, Foran, Bernie, Nankivell, Paul, Bryant, Jennifer, Sharma, Neil, Spruce, Rachel, Brooks, Jill, Batis, Nikos, Roques, Tom, Bidmead, Margaret, Yang, Huiqi, Nutting, Christopher, Tyler, Justine, Henderson, Julia, Baines, Helen, Gasnier, Anne, Miles, Elizabeth, Clark, Catharine

“…The incidence of human papillomavirus (HPV)-positive oropharyngeal cancer, a disease affecting younger patients, is rapidly increasing. Cetuximab, an epidermal…”
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Should extrapulmonary small cell cancer be managed like small cell lung cancer? by Brennan, Sinead M., Gregory, Deborah L., Stillie, Alison, Herschtal, Alan, Mac Manus, Michael, Ball, David L.

“…BACKGROUND: The aim of this study was to determine if extrapulmonary small cell carcinomas (EPSCC) should be managed using protocols similar to those for small…”
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Normal tissue considerations and dose–volume constraints in the moderately hypofractionated treatment of non-small cell lung cancer by Fleming, Cathy, Cagney, Daniel N, O’Keeffe, Serena, Brennan, Sinead M, Armstrong, John G, McClean, Brendan

“…Abstract Hypofractionated radiation therapy (RT) regimes in non-small cell lung cancer (NSCLC) have become increasingly popular with a number of international…”
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Exploring implementation of the Careful Nursing Philosophy and Professional Practice Model© in hospital‐based practice by Murphy, Sinéad, Mc Mullin, Raphael, Brennan, Sinéad, Meehan, Therese Connell

“…Aim To explore the effectiveness and feasibility of implementing the two clinical dimensions of the Careful Nursing Philosophy and Professional Practice Model©…”
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Dosimetric explanations of fatigue in head and neck radiotherapy: An analysis from the PARSPORT Phase III trial by Gulliford, Sarah L, Miah, Aisha B, Brennan, Sinead, McQuaid, Dualta, Clark, Catharine H, Partridge, Mike, Harrington, Kevin J, Morden, James P, Hall, Emma, Nutting, Christopher M

“…Abstract Background An unexpected finding from the phase III parotid sparing radiotherapy trial, PARSPORT (ISRCTN48243537, CRUK/03/005), was a statistically…”
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Hypothalamic-Pituitary Dysfunction after Irradiation of Nonpituitary Brain Tumors in Adults by Agha, Amar, Sherlock, Mark, Brennan, Sinead, O’Connor, Stephen A., O’Sullivan, Eoin, Rogers, Bairbre, Faul, Clare, Rawluk, Daniel, Tormey, William, Thompson, Christopher J.

“…Context: Hypothalamic-pituitary (HP) dysfunction is common in children treated with cranial radiotherapy (RT) for brain tumors, but there is little known about…”
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Preservation of swallowing in resected oral cavity squamous cell carcinoma: examining radiation volume effects (PRESERVE): study protocol for a randomized phase II trial by Lang, Pencilla, Contreras, Jessika, Kalman, Noah, Paterson, Claire, Bahig, Houda, Billfalk-Kelly, Astrid, Brennan, Sinead, Rock, Kathy, Read, Nancy, Venkatesan, Varagur, Sathya, Jinka, Mendez, Lucas C., MacNeil, S. Danielle, Nichols, Anthony C., Fung, Kevin, Mendez, Adrian, Winquist, Eric, Kuruvilla, Sara, Stewart, Paul, Warner, Andrew, Mitchell, Sylvia, Theurer, Julie A., Palma, David A.

“…Abstract Background Patients with resected oral cavity squamous cell carcinoma (OCSCC) are often treated with adjuvant radiation (RT) ± concomitant…”
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Factors Influencing Conformity Index in Radiotherapy for Non–Small Cell Lung Cancer by Brennan, Sinead M., M.D, Thirion, Pierre, M.D, Buckney, Steve, Shea, Carmel O, Armstrong, John, M.D

“…Abstract The radiotherapy conformity index (CI) is a useful tool to quantitatively assess the quality of radiotherapy treatment plans, and represents the…”
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3069: Prevention of osteoradionecrosis in patients with head and neck cancer treated with radiotherapy by Naseer, Amara, Brennan, Sinead, MacCarthy, Denise, O'Sullivan, Eleanor, O'Connell, John Edward, Leech, Michelle M.

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Prevention of osteoradionecrosis in patients with head and neck cancer treated with radiation therapy by Naseer, Amara, Brennan, Sinead, MacCarthy, Denise, O'Connell, John Edward, O'Sullivan, Eleanor, Leech, Michelle

“…Osteoradionecrosis is a long-term, serious side effect of head and neck radiation therapy and is associated with significant morbidity and quality of life…”
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194 Do all roads lead to Speech and Language Therapy? Evaluation of a pilot waiting-list initiative for radiation-oncology head and neck cancer patients to enhance access to Speech and Language Therapy by Higgins, Katie, Lawson, Susan, Armstrong, John, Boychak, Oleksandr, Duane, Fran, Brennan, Sinead

“…All head and neck cancer (HNC) patients receiving radiotherapy should have access to Speech and Language Therapy (SLT) for management of speech and…”
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160 Review of oropharyngeal cancer recurrences- how do they present? by O'Dwyer, Niall, Browne, Darragh, Brennan, Sinead, Duane, Frances, Armstrong, John, Boychak, Alex, McArdle, Orla

“…Oropharyngeal squamous cell cancers have a locoregional recurrence rate range of 17.3-32.5% and a distant metastatic rate of 6.5-17% at 3 years (ref1)…”
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138 Beyond Rigid Registration: The Role of Deformable Image Registration for Rescans and Replans in H&N Cancer Radiotherapy by Malone, Ciaran, Ryan, Samantha, Nicholson, Jill, Duane, Fran, McArdle, Orla, Brennan, Sinead, Tyner, Elaine, McClean, Brendan, Woods, Ruth

“…This study investigates whether spinal deviations exceeding 5mm from the planned position during Head & Neck cancer radiotherapy, detected using a rigid…”
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155 Treatment of oropharyngeal cancer during lockdown - outcomes for patients treated during the pandemic by O'Dwyer, Niall, O'Connell, Liam, Browne, Darragh, Dunne, Mary, Brennan, Sinead, Duane, Frances, Armstrong, John, Boychak, Alex, McArdle, Orla

“…The onset of the COVID-19 outbreak caused major interruptions to the entire healthcare network affecting most oncological referral, diagnosis and treatment…”
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Reply: Elective Radiotherapy or Neck Dissection for CT-Staged T1-2N0 Oral Tongue Cancer by Brennan, Sinead

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231 Gross Tumour Volume predicts survival in HPV related Oropharyngeal Squamous Cell Carcinoma by Browne, Darragh Patrick, O'Dwyer, Niall, Dunne, Mary, Connolly, Emma, Burns, Jane, McNamara, Megan, Boychak, Oleksandr, Armstrong, John, Duane, Fran, Brennan, Sinead, McArdle, Orla

“…To investigate if tumour volume (primary, nodal and combined) predicts recurrence free (RFS) and overall survival (OS) in p16+ oropharyngeal squamous cell…”
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Contouring Workshops - The Beneficial Impact on Radiation Oncology Specialist Training in Ireland by Rangaswamy, Guhan, Nicholson, Jill, Monaghan, Orla, Wallace, Neil, Foley, Daniel, Skourou, Christina, Duane, Fran, O'Neill, Brian, Thirion, Pierre, Cunningham, Moya, Brennan, Sinead, McArdle, Orla

“…One of the key components of training in Radiation Oncology is gaining knowledge in contouring tumour volumes and organs at risk for radiotherapy planning…”
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Intrafraction Motion in Surface-Guided Breast Radiation Therapy and its Implications on a Single Planning Target Volume Margin Strategy by Malone, Ciaran, Ryan, Samantha, Nicholson, Jill, McArdle, Orla, Brennan, Sinead, McCavana, Pat, McClean, Brendan, Duane, Frances

“…This study quantifies intrafraction motion in surface-guided radiation therapy (SGRT) for breast cancer and considers the need for individualized intrafraction…”
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A qualitative study to understand the barriers and facilitators in smoking cessation practices among oncology health care practitioners in one health system by Frazer, Kate, Bhardwaj, Nancy, Fox, Patricia, Lyons, Ailsa, Syed, Shiraz, Niranjan, Vikram, McCann, Amanda, Kelly, Catherine, Brennan, Sinead, Brennan, Donal, Geraghty, James, Keane, Michael P, Fitzpatrick, Patricia

“…Despite the benefits of quitting smoking for those who have cancer, including improved health outcomes and reduced therapeutic toxicities, it is unclear how…”
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Quantifying the need for a proton TPS: How many H&N patients qualify for a proton plan calculation? by Zacharatou, Christina, Bergin, Niall, O' Donovan, Cormac, McArdle, Orla, Brennan, Sinead, Cain, Sarah, Dunne, Mary, Armstrong, John, McClean, Brendan

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