Search Results - "Brennan, Linda M."

A multistep enrichment process with custom growth medium improves resuscitation of chlorine-stressed coliforms from secondary sewage effluents by Mobberley, Jennifer M., Cooley, Scott K., Widder, Mark W., Phillips, Shelby M., Melville, Angela M., Brennan, Linda M., Divito, Valerie T., van der Schalie, William H., Ozanich, Richard M., Hutchison, Janine R.

“…Resuscitation and detection of stressed total coliforms in chlorinated water samples is needed to assess and prevent health effects from adverse exposure. In…”
Get full text

Consistent production of chlorine-stressed bacteria from non-chlorinated secondary sewage effluents for use in the U.S. Environmental Protection Agency Alternate Test Procedure protocol by Hutchison, Janine R., Widder, Mark W., Brooks, Shelby M., Brennan, Linda M., Souris, Leah, Divito, Valerie T., van der Schalie, William H., Ozanich, Richard M.

“…The U.S. Environmental Protection Agency Alternative Test Procedure protocol outlines a method to produce chlorine-stressed bacteria for water quality testing…”
Get full text

A portable cell-based impedance sensor for toxicity testing of drinking water by Curtis, Theresa M, Widder, Mark W, Brennan, Linda M, Schwager, Steven J, van der Schalie, William H, Fey, Julien, Salazar, Noe

“…A major limitation to using mammalian cell-based biosensors for field testing of drinking water samples is the difficulty of maintaining cell viability and…”
Get more information

Long-term storage and impedance-based water toxicity testing capabilities of fluidic biochips seeded with RTgill-W1 cells by Brennan, Linda M., Widder, Mark W., Lee, Lucy E.J., van der Schalie, William H.

“…► Rainbow trout gill epithelial cells (RTgill-W1) are seeded onto fluidic biochips. ► Biochips can be stored for at least 78weeks at 6°C with no media…”
Get full text

Preparation and Testing of Impedance-based Fluidic Biochips with RTgill-W1 Cells for Rapid Evaluation of Drinking Water Samples for Toxicity by Brennan, Linda M, Widder, Mark W, McAleer, Michael K, Mayo, Michael W, Greis, Alex P, van der Schalie, William H

“…This manuscript describes how to prepare fluidic biochips with Rainbow trout gill epithelial (RTgill-W1) cells for use in a field portable water toxicity…”
Get full text

Evaluation and refinement of a field-portable drinking water toxicity sensor utilizing electric cell-substrate impedance sensing and a fluidic biochip by Widder, Mark W., Brennan, Linda M., Hanft, Elizabeth A., Schrock, Mary E., James, Ryan R., van der Schalie, William H.

“…The US Army's need for a reliable and field‐portable drinking water toxicity sensor was the catalyst for the development and evaluation of an electric…”
Get full text

A novel amphibian tier 2 testing protocol: A 30-week exposure of Xenopus tropicalis to the antiandrogen flutamide by Knechtges, Paul L., Sprando, Robert L., Porter, Karen L., Brennan, Linda M., Miller, Mark F., Kumsher, David M., Dennis, William E., Brown, Charles C., Clegg, Eric D.

“…In 1996, the U.S. Congress mandated the development of a screening program for endocrine‐disrupting chemicals (EDCs) using validated test systems…”
Get full text

Chronic Toxicity of Chloroform to Japanese Medaka Fish by Toussaint, Margaret W., Rosencrance, Alan B., Brennan, Linda M., Beaman, Joseph R., Wolfe, Marilyn J., Hoffmann, Florence J., Gardner, Henry S.

“…Japanese medaka (Oryzias latipes) were continually exposed in a flow-through diluter system for 9 months to measured chloroform concentrations of 0.017, 0.151,…”
Get full text

A multistep enrichment process with custom growth medium improves resuscitation of chlorine-stressed coliforms from secondary sewage effluents by Mobberley, Jennifer M., Cooley, Scott K., Widder, Mark W., Phillips, Shelby MB, Melville, Angela M., Brennan, Linda M., Divito, Valerie T., Van Der Schalie, William H., Ozanich, Richard M., Hutchison, Janine R.

“…Resuscitation and detection of stressed coliforms in treated water samples is needed to assess and prevent health effects from adverse exposure. Herein, we…”
Get full text

Chronic Toxicity of Bromodichloromethane to the Japanese Medaka (Oryzias latipes) by Toussaint, Margaret W., Rosencrance, Alan B., Brennan, Linda M., Dennis, William E., Beaman, Joseph R., Wolfe, Marilyn J., Hoffmann, Florence J., Gardner, Henry S.

“…Japanese medaka (Oryzias latipes) were continually exposed in a flow-through diluter system for 9 months to measured bromodichloromethan e (BDCM)…”
Get full text

An In Vivo Method for Using 5-Bromo-2'-deoxyuridine (BrdU) as a Marker of Chemically-Induced Hepatocellular Proliferation in the Japanese Medaka (Oryzias latipes) by Brennan, Linda M., Boncavage-Hennessey, E. Maxine, Wolfe, Marilyn J., Toussaint, Margaret W., Dennis, William E., Rosencrance, Alan B., Gardner, Henry S.

“…Japanese medaka fish ( Oryzias latipes) were used to develop an in vivo method to assess hepatocellular proliferation in a nonmammalian model. Proliferative…”
Get full text

Preparation and Testing of Impedance-based Fluidic Biochips with RTgill-W1 Cells for Rapid Evaluation of Drinking Water Samples for Toxicity by Brennan, Linda M., Widder, Mark W., McAleer, Michael K., Mayo, Michael W., Greis, Alex P., van der Schalie, William H.

Get full text

The effects of methapyrilene hydrochloride on hepatocarcinogenicity and pentobarbital-induced sleeping time in rats and mice by Brennan, L M, Creasia, D A

Get more information

Environmental Complex Mixture Toxicity Assessment by Henry S. Gardner Jr, Brennan, Linda M., Toussaint, Margaret W., Rosencrance, Alan B., E. Maxine Boncavage-Hennessey, Wolfe, Marilyn J.

“…Trichloroethylene (TCE) was found as a contaminant in the well supplying water to an aquatic testing laboratory. The groundwater was routinely screened by a…”
Get full text

An in vivo method for using 5-bromo-2'-deoxyuridine (BrdU) as a marker of chemically-induced hepatocellular proliferation in the Japanese medaka (Oryzias latipes) by BRENNAN, Linda M, BONCAVAGE-HENNESSEY, E. Maxine, WOLFE, Marilyn J, TOUSSAINT, Margaret W, DENNIS, William E, ROSENCRANCE, Alan B, GARDNER, Henry S

Get full text

A sequential study of methapyrilene hydrochloride-induced liver carcinogenesis in male F344 rats by Ohshima, M, Ward, J M, Brennan, L M, Creasia, D A

“…Methapyrilene hydrochloride [2-[2-(dimethylamino)-ethyl)-2-thenylamino)pyridine monohydrochloride (CAS: 135-23-9)]-induced hepatocarcinogenesis was studied in…”
Get more information

In vivo and in vitro NO2 exposures enhance phagocytic and tumoricidal activities of rat alveolar macrophages by Sone, S, Brennan, L M, Creasia, D A

“…Rat alveolar macrophages (AM) were exposed in vivo or in vitro to nitrogen dioxide (NO2) and subsequently tested for phagocytic and tumoricidal activities. AM…”
Get more information