Search Results - "Brennan, Francis"

Stress-induced changes in sleep in rodents: Models and mechanisms by Pawlyk, Aaron C., Morrison, Adrian R., Ross, Richard J., Brennan, Francis X.

“…Psychological stressors have a prominent effect on sleep in general, and rapid eye movement (REM) sleep in particular. Disruptions in sleep are a prominent…”
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Pharmacogenetic-guided psychiatric intervention associated with increased adherence and cost savings by Fagerness, Jesen, Fonseca, Eileen, Hess, Gregory P, Scott, Rachel, Gardner, Kathryn R, Koffler, Michael, Fava, Maurizio, Perlis, Roy H, Brennan, Francis X, Lombard, Jay

“…Pharmacogenetic testing as a means of guiding treatment decisions is beginning to see wider clinical use in psychiatry. The utility of this genetic information…”
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A Naturalistic Study of the Effectiveness of Pharmacogenetic Testing to Guide Treatment in Psychiatric Patients With Mood and Anxiety Disorders by Brennan, Francis X, Gardner, Kathryn R, Lombard, Jay, Perlis, Roy H, Fava, Maurizio, Harris, Herbert W, Scott, Rachel

“…To examine the effectiveness of genetic testing in a real-world setting and to assess its impact on clinician treatment decisions. This was a naturalistic,…”
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A high throughput in vivo assay for taste quality and palatability by Palmer, R Kyle, Long, Daniel, Brennan, Francis, Buber, Tulu, Bryant, Robert, Salemme, F Raymond

“…Taste quality and palatability are two of the most important properties measured in the evaluation of taste stimuli. Human panels can report both aspects, but…”
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Correction: A High Throughput In Vivo Assay for Taste Quality and Palatability by Palmer, R. Kyle, Long, Daniel, Brennan, Francis, Buber, Tulu, Bryant, Robert, Salemme, F. Raymond

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REM sleep: a sensitive index of fear conditioning in rats by Jha, Sushil K., Brennan, Francis X., Pawlyk, Aaron C., Ross, Richard J., Morrison, Adrian R.

“…To examine the influence of conditioned fear stimuli on sleep‐wake states, we recorded sleep in Sprague–Dawley rats after exposure to tones previously paired…”
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A rodent model of sleep disturbances in posttraumatic stress disorder: The role of context after fear conditioning by Pawlyk, Aaron C., Jha, Sushil K., Brennan, Francis X., Morrison, Adrian R., Ross, Richard J.

“…A prominent sleep disturbance, likely including a disruption of rapid eye movement sleep (REMS) continuity, characterizes posttraumatic stress disorder (PTSD)…”
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Pharmacologic antagonism of the oral aversive taste-directed response to capsaicin in a mouse brief access taste aversion assay by Long, Daniel J, Devantier, Heather R, Brennan, Francis X, Bryant, Robert W, Salemme, F Raymond, Palmer, R Kyle

“…Chemosensory signaling by the tongue is a primary determinant of ingestive behavior and is mediated by specific interactions between tastant molecules and G…”
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Long-term Effect of Cued Fear Conditioning on REM Sleep Microarchitecture in Rats by MADAN, Vibha, BRENNAN, Francis X, MANN, Graziella L, HORBAL, Apryle A, DUNN, Gregory A, ROSS, Richard J, MORRISON, Adrian R

“…To study long-term effects of conditioned fear on REM sleep (REMS) parameters in albino rats. We have investigated disturbances in sleep architecture,…”
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Effect of Petting a Dog on Immune System Function by Charnetski, Carl J., Riggers, Sandra, Brennan, Francis X.

“…The present study assessed the effect of petting a dog on secretory immunoglobulin A (IgA) levels. 55 college students were randomly assigned to either an…”
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The Potential Utility of Pharmacogenetic Testing in Psychiatry by Lombard, Jay, Scott, Rachel, Brennan, Francis X., Gardner, Kathryn R.

“…Over the last decade, pharmacogenetics has become increasingly significant to clinical practice. Psychiatric patients, in particular, may benefit from…”
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Quantitative assessment of TRPM5-dependent oral aversiveness of pharmaceuticals using a mouse brief-access taste aversion assay by Devantier, Heather R, Long, Daniel J, Brennan, Francis X, Carlucci, Stacy A, Hendrix, Cynthia, Bryant, Robert W, Salemme, F Raymond, Palmer, R Kyle

“…Many orally administered pharmaceuticals are regarded by humans as aversive, most often described as ‘bitter’. Taste aversiveness often leads to patient…”
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Low doses of interleukin-1β improve the leverpress avoidance performance of Sprague–Dawley rats by Brennan, Francis X., Beck, Kevin D., Servatius, Richard J.

“…Recent research has indicated that the pro-inflammatory cytokines, particularly interleukin-1β (IL-1β), can affect learning and memory. We injected male…”
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Proinflammatory cytokines differentially affect leverpress avoidance acquisition in rats by Brennan, Francis X, Beck, Kevin D, Servatius, Richard J

“…Recent evidence indicates that the pro-inflammatory cytokines (PICs) can affect learning and memory processes. To examine the effect of the PICs on leverpress…”
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Centrally administered tumor necrosis factor-α facilitates the avoidance performance of Sprague–Dawley rats by Brennan, Francis X., Tieder, J. Bernard

“…In addition to their immunological functions, recent research has indicated that the pro-inflammatory cytokines can influence learning and memory processes. We…”
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Sexual Frequency and Salivary Immunoglobulin A (IgA) by Charnetski, Carl J., Brennan, Francis X.

“…112 college students reported the frequency of their sexual encounters and were divided into four categories: none, infrequent (less than once a week),…”
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Corticotropin-releasing factor microinjection into the central nucleus of the amygdala alters REM sleep by Pawlyk, Aaron C, Sanford, Larry D, Brennan, Francis X, Morrison, Adrian R, Ross, Richard J

“…Psychological stressors have a prominent effect on rapid eye movement sleep (REMS) in humans and animals. We hypothesized that the stress-related neurochemical…”
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Stress interacts with peripheral cholinesterase inhibitors to cause central nervous system effects by Beck, Kevin D., Brennan, Francis X., Moldow, Roberta L., Ottenweller, John E., Zhu, Guanping, Servatius, Richard J.

“…Pyridostigmine bromide (PB), a peripheral cholinesterase inhibitor, has been shown to have central cholinesterase inhibition properties under certain…”
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Assessment of Erenumab Safety and Efficacy in Patients With Migraine With and Without Aura: A Secondary Analysis of Randomized Clinical Trials by Ashina, Messoud, Goadsby, Peter J, Dodick, David W, Tepper, Stewart J, Xue, Fei, Zhang, Feng, Brennan, Francis, Paiva da Silva Lima, Gabriel

“…Migraine with aura may respond differently to therapies than migraine without aura. Individuals with migraine with aura have an elevated vascular risk,…”
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Ethanol consumption improves avoidance learning in rats: role of deprivation interval by Brennan, Francis X., Stromberg, Michael F.

“…Voluntary oral self-administration of ethanol in rats has been used to model ethanol consumption and abuse in human beings, with contradictory results. The…”
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