Search Results - "Brenerman, Boris"
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Thyroid hormone signaling specifies cone subtypes in human retinal organoids
Published in Science (American Association for the Advancement of Science) (12-10-2018)“…The mechanisms underlying specification of neuronal subtypes within the human nervous system are largely unknown. The blue (S), green (M), and red (L) cones of…”
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DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes
Published in Nucleic acids research (30-01-2015)“…We explore the role of DNA damage processing in the progression of cognitive decline by creating a new mouse model. The new model is a cross of a common…”
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Retinoic acid signaling regulates spatiotemporal specification of human green and red cones
Published in PLoS biology (11-01-2024)“…Trichromacy is unique to primates among placental mammals, enabled by blue (short/S), green (medium/M), and red (long/L) cones. In humans, great apes, and Old…”
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Base excision repair capacity in informing healthspan
Published in Carcinogenesis (New York) (01-12-2014)“…Base excision repair (BER) is a frontline defense mechanism for dealing with many common forms of endogenous DNA damage, several of which can drive mutagenic…”
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Retinoic acid signaling regulates spatiotemporal specification of human green and red cones
Published in PLoS biology (01-01-2024)Get full text
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Development of a Cell-Based Assay for Measuring Base Excision Repair Responses
Published in Scientific reports (11-10-2017)“…Base excision repair (BER) is the predominant pathway for coping with most forms of hydrolytic, oxidative or alkylative DNA damage. Measuring BER capacity in…”
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Tumor‐associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes
Published in Environmental and molecular mutagenesis (01-03-2017)“…Base excision repair (BER) is the major pathway for coping with most forms of endogenous DNA damage, and defects in the process have been associated with…”
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