Search Results - "Brelsfoard, Jennifer M"

Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits following Traumatic Brain Injury in Mice by Madathil, Sindhu K, Carlson, Shaun W, Brelsfoard, Jennifer M, Ye, Ping, D'Ercole, A Joseph, Saatman, Kathryn E

“…Traumatic brain injury (TBI) survivors often suffer from long-lasting cognitive impairment that stems from hippocampal injury. Systemic administration of…”
Get full text

Repeated Closed Head Injury in Mice Results in Sustained Motor and Memory Deficits and Chronic Cellular Changes by Bolton Hall, Amanda N, Joseph, Binoy, Brelsfoard, Jennifer M, Saatman, Kathryn E

“…Millions of mild traumatic brain injuries (TBIs) occur every year in the United States, with many people subject to multiple head injuries that can lead to…”
Get full text

Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment ("chemobrain") by Keeney, Jeriel T R, Ren, Xiaojia, Warrier, Govind, Noel, Teresa, Powell, David K, Brelsfoard, Jennifer M, Sultana, Rukhsana, Saatman, Kathryn E, Clair, Daret K St, Butterfield, D Allan

“…Chemotherapy-induced cognitive impairment (CICI) is now widely recognized as a real and too common complication of cancer chemotherapy experienced by an…”
Get full text

Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin by Srodulski, Sarah, Sharma, Savita, Bachstetter, Adam B, Brelsfoard, Jennifer M, Pascual, Conrado, Xie, Xinmin Simon, Saatman, Kathryn E, Van Eldik, Linda J, Despa, Florin

“…We recently found that brain tissue from patients with type-2 diabetes (T2D) and cognitive impairment contains deposits of amylin, an amyloidogenic hormone…”
Get full text

Calpastatin overexpression limits calpain-mediated proteolysis and behavioral deficits following traumatic brain injury by Schoch, Kathleen M., Evans, Heather N., Brelsfoard, Jennifer M., Madathil, Sindhu K., Takano, Jiro, Saido, Takaomi C., Saatman, Kathryn E.

“…Traumatic brain injury (TBI) results in abrupt, initial cell damage leading to delayed neuronal death. The calcium-activated proteases, calpains, are known to…”
Get full text

Rit GTPase signaling promotes immature hippocampal neuronal survival by Cai, Weikang, Carlson, Shaun W, Brelsfoard, Jennifer M, Mannon, Catherine E, Moncman, Carole L, Saatman, Kathryn E, Andres, Douglas A

“…The molecular mechanisms governing the spontaneous recovery seen following brain injury remain elusive, but recent studies indicate that injury-induced…”
Get full text