Search Results - "Brelén, Mårten E."

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    Diabetes mellitus and risk of age-related macular degeneration: a systematic review and meta-analysis by Chen, Xue, Rong, Shi Song, Xu, Qihua, Tang, Fang Yao, Liu, Yuan, Gu, Hong, Tam, Pancy O S, Chen, Li Jia, Brelén, Mårten E, Pang, Chi Pui, Zhao, Chen

    Published in PloS one (19-09-2014)
    “…Age-related macular degeneration (AMD) is a major cause of severe vision loss in elderly people. Diabetes mellitus is a common endocrine disorder with serious…”
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    Elevated angiopoietin 2 in aqueous of patients with neovascular age related macular degeneration correlates with disease severity at presentation by Ng, Danny S., Yip, Yolanda W., Bakthavatsalam, Malini, Chen, Li J., Ng, Tse K., Lai, Timothy Y., Pang, Calvin P., Brelén, Mårten E.

    Published in Scientific reports (27-03-2017)
    “…Angiopoietin 2 (ANG2) is a proangiogenic cytokine which may have an implication in neovascular age related macular degeneration (nAMD). In 24 eyes of 24…”
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    Electrophysiological Studies in Thyroid Associated Orbitopathy: A Systematic Review by Iao, Tiara W. U., Rong, Shi Song, Ling, An Ni, Brelén, Mårten E., Young, Alvin Lerrmann, Chong, Kelvin K. L.

    Published in Scientific reports (21-09-2017)
    “…Dysthyroid optic neuropathy (DON) is the commonest cause of blindness in thyroid associated orbitopathy (TAO). While diagnosis remains clinical, objective…”
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    Identification of PGF as a New Gene for Neovascular Age-Related Macular Degeneration in a Chinese Population by Chen, Li Jia, Ma, Li, Chu, Wai Kit, Lai, Timothy Y Y, Chen, Haoyu, Brelén, Mårten E, Rong, Shi Song, Young, Alvin L, Tam, Pancy O S, Zhang, Mingzhi, Pang, Chi Pui

    “…To determine the associations of the VEGFA, VEGFB, and placental growth factor (PGF) genes with neovascular age-related macular degeneration (nAMD) and…”
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    RIP3-mediated microglial necroptosis promotes neuroinflammation and neurodegeneration in the early stages of diabetic retinopathy by Huang, Zijing, Liang, Jiajian, Chen, Shaolang, Ng, Tsz Kin, Brelén, Marten E., Liu, Qingping, Yang, Rucui, Xie, Biyao, Ke, Shuping, Chen, Weiqi, Huang, Dingguo

    Published in Cell death & disease (29-03-2023)
    “…Diabetic retinopathy (DR) is a leading cause of blindness that poses significant public health concerns worldwide. Increasing evidence suggests that…”
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    Flipped Classroom Case Learning vs Traditional Lecture-Based Learning in Medical School Ophthalmology Education: A Randomized Trial by Chan, Poemen P., Lee, Vivian W.Y., Yam, Jason C., Brelén, Marten E., Kit, Chu Wai, Wan, Kelvin H., Chen, Li Jia, Tham, Clement C, Pang, Chi Pui

    Published in Academic medicine (01-09-2023)
    “…To address the problem of teaching noncore specialties, for which there is often limited teaching time and low student engagement, a flipped classroom case…”
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    Identification and characterization of a novel promoter variant in placental growth factor for neovascular age-related macular degeneration by Ma, Li, Ng, Tsz Kin, Chen, Haoyu, Brelén, Marten E., Lai, Timothy Y.Y., Ho, Mary, Tam, Pancy O.S., Young, Alvin L., Chen, Weiqi, Tham, Clement C., Pang, Chi Pui, Chen, Li Jia

    Published in Experimental eye research (01-10-2019)
    “…Intronic variants in the placental growth factor (PGF) gene have been associated with neovascular age-related macular degeneration (AMD). This study is to…”
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    Intraorbital implantation of a stimulating electrode for an optic nerve visual prosthesis. Case report by Brelén, Mårten E, De Potter, Patrick, Gersdorff, Michel, Cosnard, Guy, Veraart, Claude, Delbeke, Jean

    Published in Journal of neurosurgery (01-04-2006)
    “…Research into visual prosthetics is expected to revolutionize the treatment of blind patients with incurable outer retinal degenerative disease. Substantial…”
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    Ocular symptoms as the initial clinical manifestations in patients with extraocular tumors by Zheng, Jianlong, Chen, Weiqi, Huang, Dingguo, Wang, Yifan, Zheng, Dezhi, Zhou, Lingling, Brelén, Marten E, Huang, Zijing

    Published in Annals of translational medicine (01-03-2021)
    “…Due to the variety of clinical presentation, some tumors may be concealed and easily misdiagnosed, leading to delays in management. We report a series of…”
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    Treatment of polypoidal choroidal vasculopathy by photodynamic therapy, aflibercept and dexamethasone triple therapy by Ho, Mary, Woo, Donald C. F., Chan, Vesta C. K., Young, Alvin L., Brelen, Marten E.

    Published in Scientific reports (16-11-2016)
    “…Polypoidal choroidal vasculopathy is a relatively common type of degenerative macular disease among the Chinese population. This study aims to describe the…”
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    Association of common variants in TCF4 and PTPRG with Fuchs' corneal dystrophy: a systematic review and meta-analysis by Lau, Lawrence C M, Ma, Li, Young, Alvin L, Rong, Shi Song, Jhanji, Vishal, Brelen, Marten E, Pang, Chi Pui, Chen, Li Jia

    Published in PloS one (09-10-2014)
    “…A meta-analysis of TCF4 and PTPRG gene variants in Fuchs' corneal dystrophy (FCD). To identify novel genetic markers in patients with FCD in different ethnic…”
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    Evaluation of the association of C5 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy by Liu, Ke, Ma, Li, Lai, Timothy Y Y, Brelen, Marten E, Tam, Pancy O S, Tham, Clement C, Pang, Chi Pui, Chen, Li Jia

    Published in Eye and vision (Novato, Calif.) (07-11-2019)
    “…Neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) are sight-threatening maculopathies with both environmental and…”
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    Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Treating Choroidal Metastasis from Non-small Cell Lung Cancer: A 10-Year Review by Chee, Arnold SH, Mak, Andrew CY, Kam, Ka Wai, Li, Molly SC, Ho, Mary, Brelen, Marten E., Chen, Li Jia, Yip, Wilson WK, Young, Alvin L.

    Published in Retina (Philadelphia, Pa.) (23-10-2024)
    “…Purpose: To describe the clinical characteristics of choroidal metastasis (CM) in non-small cell lung carcinoma (NSCLC) patients and report treatment outcomes…”
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    Association of Genetic Variants with Polypoidal Choroidal Vasculopathy: A Systematic Review and Updated Meta-analysis by Ma, Li, Li, Zhen, Liu, Ke, Rong, Shi Song, Brelen, Marten E, Young, Alvin L, Kumaramanickavel, Govindasamy, Pang, Chi Pui, Chen, Haoyu, Chen, Li Jia

    Published in Ophthalmology (Rochester, Minn.) (01-09-2015)
    “…A systematic review and meta-analysis of the genetic association with polypoidal choroidal vasculopathy (PCV) and the genetic difference between PCV and…”
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    Untargeted metabolomic analysis of aqueous humor in diabetic macular edema by Chu, Kai On, Chan, Tina InLam, Chan, Kwok Ping, Yip, Yolanda WongYing, Bakthavatsalam, Malini, Wang, Chi Chiu, Pang, Chi Pui, Brelen, Marten E

    Published in Molecular vision (19-08-2022)
    “…BackgroundThe mechanism of diabetic macular edema (DME) was explored by comparing the intraocular metabolite profiles of the aqueous humor of patients with DME…”
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