Search Results - "Breittmayer, JP"

Revaluation of the role of cholesterol in stabilizing rafts implicated in T cell receptor signaling by Rouquette-Jazdanian, Alexandre K., Pelassy, Claudette, Breittmayer, Jean-Philippe, Aussel, Claude

“…T lymphocytes contain two kinetic pools of cholesterol extractable with methyl-β-cyclodextrin (m-β-CD): a fast pool (31.5%, t 1 / 2 = 17 s) and a slow pool…”
Get full text

Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo by Wakkach, Abdelilah, Fournier, Nathalie, Brun, Valérie, Breittmayer, Jean-Philippe, Cottrez, Françoise, Groux, Hervé

“…Active suppression is mediated by a subpopulation of CD4 + T cells that prevents autoimmunity. However, the mechanisms involved in their differentiation in…”
Get full text

Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse by Rodriguez, Anne-Marie, Pisani, Didier, Dechesne, Claude A, Turc-Carel, Claude, Kurzenne, Jean-Yves, Wdziekonski, Brigitte, Villageois, Albert, Bagnis, Claude, Breittmayer, Jean-Philippe, Groux, Hervé, Ailhaud, Gérard, Dani, Christian

“…Here, we report the isolation of a human multipotent adipose-derived stem (hMADS) cell population from adipose tissue of young donors. hMADS cells display…”
Get full text

A Comparative Study between T Regulatory Type 1 and CD4+CD25+ T Cells in the Control of Inflammation by Foussat, Arnaud, Cottrez, Francoise, Brun, Valerie, Fournier, Nathalie, Breittmayer, Jean-Philippe, Groux, Herve

“…There is now compelling evidence that CD4(+)CD25(+) T cells play a major role in the maintenance of tolerance. Besides CD4(+)CD25(+) T cells, different…”
Get full text

The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal by Le Gall, M, Chambard, J C, Breittmayer, J P, Grall, D, Pouysségur, J, Van Obberghen-Schilling, E

“…Anchorage removal like growth factor removal induces apoptosis. In the present study we have characterized signaling pathways that can prevent this cell death…”
Get full text

Metabolic labelling of membrane microdomains/rafts in Jurkat cells indicates the presence of glycerophospholipids implicated in signal transduction by the CD3 T-cell receptor by Rouquette-Jazdanian, Alexandre K, Pelassy, Claudette, Breittmayer, Jean-Philippe, Cousin, Jean-Louis, Aussel, Claude

“…Cell membranes contain sphingolipids and cholesterol, which cluster together in distinct domains called rafts. The outer-membrane leaflet of these peculiar…”
Get full text

Cholera Toxin B-Subunit Prevents Activation and Proliferation of Human CD4+ T Cells by Activation of a Neutral Sphingomyelinase in Lipid Rafts by Rouquette-Jazdanian, Alexandre K, Foussat, Arnaud, Lamy, Laurence, Pelassy, Claudette, Lagadec, Patricia, Breittmayer, Jean-Philippe, Aussel, Claude

“…The inhibition of human CD4+ T lymphocyte activation and proliferation by cholera toxin B-subunit (CTB) is a well-established phenomenon; nevertheless, the…”
Get full text

Apoptosis of immature thymocytes mediated by E2/CD99 by Bernard, G, Breittmayer, JP, de Matteis, M, Trampont, P, Hofman, P, Senik, A, Bernard, A

“…E2/CD99 is a 32-kDa transmembrane molecule that does not belong to any known family of proteins. It appears to regulate adhesion properties of T cells as…”
Get full text

A New Genetic Locus Controlling Growth and Proliferation in Drosophila melanogaster by Raisin, Sophie, Pantalacci, Sophie, Breittmayer, Jean-Philippe, Leopold, Pierre

“…Multicellular organisms grow through both proliferation and growth of their individual cells. We have conducted a P-element-based misexpression screen for…”
Get full text

Mature Human Thymocytes Migrate on Laminin-5 with Activation of Metalloproteinase-14 and Cleavage of CD44 by Vivinus-Nebot, Mylene, Rousselle, Patricia, Breittmayer, Jean-Philippe, Cenciarini, Claire, Berrih-Aknin, Sonia, Spong, Suzanne, Nokelainen, Pasi, Cottrez, Francoise, Marinkovich, M. Peter, Bernard, Alain

“…We have previously shown that laminin-5 is expressed in the human thymic medulla, in which mature thymocytes are located. We now report that laminin-5 promotes…”
Get full text

Priming by Microbial Antigens from the Intestinal Flora Determines the Ability of CD4+ T Cells to Rapidly Secrete IL-4 in BALB/c Mice Infected with Leishmania major by Julia, Valerie, McSorley, Stephen S, Malherbe, Laurent, Breittmayer, Jean-Philippe, Girard-Pipau, Fernand, Beck, Alain, Glaichenhaus, Nicolas

“…Infection of BALB/c mice with Leishmania major results in the rapid accumulation of IL-4 transcripts within CD4(+) T cells that react to the parasite…”
Get full text

Diadenosine polyphosphates as antagonists of the endogenous P2Y(1) receptor in rat brain capillary endothelial cells of the B7 and B10 clones by Vigne, P, Breittmayer, J P, Frelin, C

“…1. Diadenosine polyphosphates (Ap(n)As, n=2 - 7) are considered as stress mediators in the cardiovascular system. They act both via identified P2 purinoceptors…”
Get full text

Endothelin-1 as a mediator of endothelial cell-pericyte interactions in bovine brain capillaries by Dehouck, M P, Vigne, P, Torpier, G, Breittmayer, J P, Cecchelli, R, Frelin, C

“…Endothelial cells and pericytes are closely associated in brain capillaries. Together with astrocytic foot processes, they form the blood-brain barrier…”
Get more information

CD95 (Fas/APO-1) induces an increased phosphatidylserine synthesis that precedes its externalization during programmed cell death by Aussel, Claude, Pelassy, Claudette, Breittmayer, Jean Philippe

“…CD95 (Fas, APO-1)-induced programmed cell death (apoptosis) in T cell lines is accompanied by a rapid flip-flop of phosphatidylserine (PtdSer). Externalization…”
Get full text

Submicromolar La3+ concentrations block the calcium release-activated channel, and impair CD69 and CD25 expression in CD3- or thapsigargin-activated Jurkat cells by Aussel, C, Marhaba, R, Pelassy, C, Breittmayer, J P

“…The calcium release-activated channel (CRAC) opened in Jurkat cells activated either with CD3 monoclonal antibody or the endoplasmic reticulum Ca2(+)-ATPase…”
Get full text

Allosteric inhibition of endothelin ETA receptors by 3, 5-dibromosalicylic acid by Blandin, V, Vigne, P, Breittmayer, J P, Frelin, C

“…Derivatives of salicylic acid (SA) and benzoic acid prevent endothelin-1 (ET-1) binding to ETA receptors. This study analyzed actions of 30 derivatives of…”
Get more information

The E2 molecule (CD99) specifically triggers homotypic aggregation of CD4+ CD8+ thymocytes by Bernard, G, Zoccola, D, Deckert, M, Breittmayer, JP, Aussel, C, Bernard, A

“…We have previously described E2 as a 32-kDa transmembrane glycoprotein displaying an isomorphism, as two epitopes (defined by mAbs O662 and L129) are widely…”
Get full text

Regulation of phosphatidylserine exposure at the cell surface by the serine–base exchange enzyme system during CD95-induced apoptosis by Pelassy, Claudette, Breittmayer, Jean-Philippe, Aussel, Claude

“…Early in the apoptotic process, CD95 induces a translocation of phosphatidylserine (PtdSer) from the inner to the outer leaflet of the cellular plasma…”
Get full text

Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism by Talbodec, A, Berkane, N, Blandin, V, Breittmayer, J P, Ferrari, E, Frelin, C, Vigne, P

“…Aspirin is a commonly used drug with a wide pharmacological spectrum including antiplatelet, anti-inflammatory, and neuroprotective actions. This study shows…”
Get more information

Early CD4+ T Cell Recovery in Human Immunodeficiency Virus-Infected Patients Receiving Effective Therapy Is Related to a Down-Regulation of Apoptosis and Not to Proliferation by Roger, Pierre-Marie, Breittmayer, Jean-Philippe, Durant, Jacques, Sanderson, Frédéric, Ceppi, Carole, Brignone, Christelle, Cua, Eric, Clevenbergh, Philippe, Fuzibet, Jean-Gabriel, Pesce, Alain, Bernard, Alain, Dellamonica, Pierre

“…This prospective study investigated the contributions of apoptosis and proliferation of CD4+ T cells obtained by the introduction of a new antiretroviral…”
Get full text