Search Results - "Breitner, J C"

Intranasal insulin improves cognition and modulates β-amyloid in early AD by REGER, M. A, WATSON, G. S, MEHTA, P, CRAFT, S, GREEN, P. S, WILKINSON, C. W, BAKER, L. D, CHOLERTON, B, FISHEL, M. A, PLYMATE, S. R, BREITNER, J. C. S, DEGROODT, W

“…Reduced brain insulin signaling and low CSF-to-plasma insulin ratios have been observed in patients with Alzheimer disease (AD). Furthermore,…”
Get full text

Correction: Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation by Chuang, Y-F, An, Y., Bilgel, M., Wong, D. F., Troncoso, J. C., O’Brien, R. J., Breitner, J. C., Ferrucci, L., Resnick, S. M., Thambisetty, M.

Get full text

Occupational exposure to pesticides increases the risk of incident AD: The Cache County Study by HAYDEN, K. M, NORTON, M. C, DARCEY, D, OSTBYE, T, ZANDI, P. P, BREITNER, J. C. S, WELSH-BOHMER, K. A

“…Commonly used organophosphate and organochlorine pesticides inhibit acetylcholinesterase at synapses in the somatic, autonomic, and central nervous systems and…”
Get full text

Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease by LI, G, LARSON, E. B, SONNEN, J. A, SHOFER, J. B, PETRIE, E. C, SCHANTZ, A, PESKIND, E. R, RASKIND, M. A, BREITNER, J. C. S, MONTINE, T. J

“…Treatment with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitors ("statins") has been associated in some epidemiologic studies with reduced risk of…”
Get full text

Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation by Chuang, Y-F, An, Y, Bilgel, M, Wong, D F, Troncoso, J C, O'Brien, R J, Breitner, J C, Ferrucci, L, Resnick, S M, Thambisetty, M

“…Understanding how midlife risk factors influence age at onset (AAO) of Alzheimer’s disease (AD) may provide clues to delay disease expression. Although midlife…”
Get full text

Risk of dementia and AD with prior exposure to NSAIDs in an elderly community-based cohort by BREITNER, J. C. S, HANEUSE, S. J. P. A, WALKER, R, DUBLIN, S, CRANE, P. K, GRAY, S. L, LARSON, E. B

“…Nonsteroidal anti-inflammatory drugs (NSAIDs) may prevent Alzheimer dementia (AD). We analyzed the association of prior NSAID exposure with incident dementia…”
Get full text

The association of psychotropic medication use with the cognitive, functional, and neuropsychiatric trajectory of Alzheimer's disease by Rosenberg, P. B., Mielke, M. M., Han, D., Leoutsakos, J. S., Lyketsos, C. G., Rabins, P. V., Zandi, P. P., Breitner, J. C. S., Norton, M. C., Welsh-Bohmer, K. A., Zuckerman, I. H., Rattinger, G. B., Green, R. C., Corcoran, C., Tschanz, J. T.

“…Objective The use of psychotropic medications in Alzheimer's disease (AD) has been associated with both deleterious and potentially beneficial outcomes. We…”
Get full text

NSAID use and dementia risk in the Cardiovascular Health Study : Role of APOE and NSAID type by SZEKELY, C. A, BREITNER, J. C. S, FITZPATRICK, A. L, REA, T. D, PSATY, B. M, KULLER, L. H, ZANDI, P. P

“…Epidemiologic and laboratory studies suggest that nonsteroidal antiinflammatory drugs (NSAIDs) reduce risk of Alzheimer disease (AD). We therefore investigated…”
Get full text

Mental and Behavioral Disturbances in Dementia: Findings From the Cache County Study on Memory in Aging by Lyketsos, Constantine G., Steinberg, Martin, Tschanz, JoAnn T., Norton, Maria C., Steffens, David C., Breitner, John C.S.

“…OBJECTIVE: The authors report findings from a study of 5,092 community residents who constituted 90% of the elderly resident population of Cache County, Utah…”
Get full text

Conversion to dementia from mild cognitive disorder : The Cache County Study by TSCHANZ, J. T, WELSH-BOHMER, K. A, BREITNER, J. C. S, LYKETSOS, C. G, CORCORAN, C, GREEN, R. C, HAYDEN, K, NORTON, M. C, ZANDI, P. P, TOONE, L, WEST, N. A

“…To examine 3-year rates of conversion to dementia, and risk factors for such conversion, in a population-based sample with diverse types of cognitive…”
Get full text

Does NSAID use modify cognitive trajectories in the elderly? : The Cache County Study by HAYDEN, K. M, ZANDI, P. P, BREITNER, J. C. S, WELSH-BOHMER, K. A, KHACHATURIAN, A. S, SZEKELY, C. A, FOTUHI, M, NORTON, M. C, TSCHANZ, J. T, PIEPER, C. F, CORCORAN, C, LYKETSOS, C. G

“…Epidemiologic studies have suggested that nonsteroidal anti-inflammatory drugs (NSAIDs) may be useful for the prevention of Alzheimer disease (AD). By…”
Get full text

Nonsteroidal anti-inflammatory drugs are associated with increased neuritic plaques by SONNEN, J. A, LARSON, E. B, WALKER, R. L, HANEUSE, S, CRANE, P. K, GRAY, S. L, BREITNER, J. C. S, MONTINE, T. J

“…Observational and experimental studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer disease (AD); however, clinical…”
Get full text

A hierarchy of predictors for dementia-free survival in old-age: results of the AgeCoDe study by Luck, T., Riedel-Heller, S. G., Luppa, M., Wiese, B., Bachmann, C., Jessen, F., Bickel, H., Weyerer, S., Pentzek, M., König, H.-H., Prokein, J., Eisele, M., Wagner, M., Mösch, E., Werle, J., Fuchs, A., Brettschneider, C., Scherer, M., Breitner, J. C. S., Maier, W.

“…Objective Progression from cognitive impairment (CI) to dementia is predicted by several factors, but their relative importance and interaction are unclear…”
Get full text

Risk factors for neuropsychiatric symptoms in dementia: the Cache County Study by Steinberg, M., Corcoran, C., Tschanz, J.T., Huber, C., Welsh-Bohmer, K., Norton, M.C., Zandi, P., Breitner, J.C.S., Steffens, D.C., Lyketsos, C.G.

“…Objective To investigate the probability of individual neuropsychiatric symptoms in dementia patients as a function of eight risk factors. Methods In the Cache…”
Get full text

Antioxidant intake and cognitive function of elderly men and women: the Cache County Study by Wengreen, H J, Munger, R G, Corcoran, C D, Zandi, P, Hayden, K M, Fotuhi, M, Skoog, I, Norton, M C, Tschanz, J, Breitner, J C S, Welsh-Bohmer, K A

“…We prospectively examined associations between intakes of antioxidants (vitamins C, vitamin E, and carotene) and cognitive function and decline among elderly…”
Get more information

Twin pairs discordant for neuropathologically confirmed Lewy body dementia by Sheei-Meei Wang, C, Burke, J R, Steffens, D C, Hulette, C M, Breitner, J C S, Plassman, B L

“…Aim: Little is known about the concordance rate in twins for dementia with Lewy bodies (DLB). The rate of agreement between clinical and pathological diagnoses…”
Get full text

Vascular factors predict rate of progression in Alzheimer disease by Mielke, M M, Rosenberg, P B, Tschanz, J, Cook, L, Corcoran, C, Hayden, K M, Norton, M, Rabins, P V, Green, R C, Welsh-Bohmer, K A, Breitner, J C S, Munger, R, Lyketsos, C G

“…While there is considerable epidemiologic evidence that cardiovascular risk factors increase risk of incident Alzheimer disease (AD), few studies have examined…”
Get full text

Observations on DSM-5 Mild Neurocognitive Disorder vs. its predecessor, Mild Cognitive Impairment by Breitner, J. C. S.

Get full text

Alzheimer's disease in the NAS-NRC Registry of aging twin veterans, IV. Performance characteristics of a two-stage telephone screening procedure for Alzheimer's dementia by Gallo, J J, Breitner, J C

“…In the course of a large twin study of Alzheimer's disease we used a two-stage telephone screening procedure. The modified Telephone Interview for Cognitive…”
Get more information

Enhanced Cognitive Performance with Estrogen Use in Nondemented Community-Dwelling Older Women by Steffens, David C., Norton, Maria C., Plassman, Brenda L., Tschanz, Jo Ann T., Wyse, Bonita W., Welsh-Bohmer, Kathleen A., Anthony, James C., Breitner, John C. S.

“…OBJECTIVE: To examine the association between history of postmenopausal estrogen use and cognitive function in a large sample of nondemented community‐dwelling…”
Get full text