Search Results - "Breitman, T R"

Retinoylation of proteins in mammalian cells by Breitman, T R, Takahashi, N

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Tributyrin : a prodrug of butyric acid for potential clinical application in differentiation therapy by ZI-XING CHEN, BREITMAN, T. R

“…Butyric acid (BA) induces cytodifferentiation in vitro of a wide variety of neoplastic cells. The potential clinical utility of BA is limited by the apparent…”
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Retinoic Acid Acylation (Retinoylation) of a Nuclear Protein in the Human Acute Myeloid Leukemia Cell Line HL60 by Takahashi, N, Breitman, T R

“…all-trans-Retinoic acid is a potent inducer in vitro of the differentiation of the human acute myeloid leukemia cell line HL60 and of fresh cells from patients…”
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N-(4-hydroxyphenyl)retinamide (Fenretinide) in combination with retinoic acid enhances differentiation and retinoylation of proteins by TAKAHASHI, N, SAUSVILLE, E. A, BREITMAN, T. R

“…The synthetic retinoid, N-(4-hydroxyphenyl)retinamide (4-HPR; Fenretinide), is a cancer chemopreventive and antiproliferative agent whose mechanism of action…”
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Induction of Differentiation of the Human Promyelocytic Leukemia Cell Line (HL-60) by Retinoic Acid by Breitman, T. R., Selonick, Stuart E., Collins, Steven J.

“…The HL-60 cell line, derived from a patient with acute promyelocytic leukemia, proliferates continuously in suspension culture and consists predominantly…”
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Conformationally Defined Retinoic Acid Analogues. 4. Potential New Agents for Acute Promyelocytic and Juvenile Myelomonocytic Leukemias by Muccio, Donald D, Brouillette, Wayne J, Breitman, Theodore R, Taimi, Mohammed, Emanuel, Peter D, Zhang, Xiao-kun, Chen, Guo-quan, Sani, Brahma P, Venepally, Pratap, Reddy, Lakshmi, Alam, Muzaffar, Simpson-Herren, Linda, Hill, Donald L

“…We recently synthesized several conformationally constrained retinoic acid (RA) analogues [8-(2‘-cyclohexen-1‘-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acids…”
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Retinoylation of vimentin in the human myeloid leukemia cell line HL60 by TAKAHASHI, N, BREITMAN, T. R

“…Retinoylation (retinoic acid acylation) is a posttranslational modification of proteins occurring in many eukaryotic cell lines. The widespread occurrence of…”
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Retinoylation of HL-60 proteins. Comparison to labeling by palmitic and myristic acids by Takahashi, N, Breitman, T.R.

“…Recent studies suggest that a retinoic acid (RA) nuclear receptor or a retinoylated nuclear protein may be involved in the action of RA. We showed previously…”
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Combinations of Recombinant Human Interferons and Retinoic Acid Synergistically Induce Differentiation of the Human Promyelocytic Leukemia Cell Line HL-60 by Hemmi, Hiromichi, Breitman, Theodore R.

“…The human acute promyelocytic leukemia cell line HL-60 is induced to differentiate into morphologically and functionally mature monocytelike cells by…”
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Retinoylation of proteins in rat liver, kidney, and lung in vivo by Myhre, A M, Takahashi, N, Blomhoff, R, Breitman, T R, Norum, K R

“…Retinoylation (retinoic acylation) is a posttranslational modification of proteins occurring in a variety of cell types in vitro. This study was done to…”
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Terminal Differentiation of Human Promyelocytic Leukemic Cells in Primary Culture in Response to Retinoic Acid by Breitman, T.R., Collins, Steven J., Keene, B.R.

“…The recent finding that retinoic acid induces terminal granulocytic differentiation of the human promyelocytic leukemia cell line, HL-60, prompted an…”
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Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid by Breitman, TR, Collins, SJ, Keene, BR

“…The recent finding that retinoic acid induces terminal granulocytic differentiation of the human promyelocytic leukemia cell line, HL-60, prompted an…”
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Retinoylation of proteins in leukemia, embryonal carcinoma, and normal kidney cell lines: differences associated with differential responses to retinoic acid by Takahashi, N, Breitman, T R

“…In HL60 cells a nuclear protein of Mr 55,000 is retinoylated, with the formation of a thioester bond. To gain further knowledge on the role of retinoylation we…”
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Potentiation of retinoic acid-induced differentiation of human acute promyelocytic leukemia NB4 cells by butyric acid, tributyrin, and hexamethylene bisacetamide by Taimi, M, Chen, Z X, Breitman, T R

“…Cytodifferentiation therapy by all-trans-retinoic acid (RA) for acute promyelocytic leukemia patients is encouraging in spite of several limitations preventing…”
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Covalent Modification of Proteins by Ligands of Steroid Hormone Receptors by Takahashi, Noriko, Breitman, Theodore R.

“…Retinoylation, acylation with retinoic acid (RA), is a covalent modification of proteins occurring in a variety of eukaryotic cell lines. In this study, we…”
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Potential applications of cytodifferentiation therapy in hematologic malignancies by Breitman, T R, Chen, Z X, Takahashi, N

“…Retinoids, including retinoic acid (RA), are naturally occurring and synthetic analogs of vitamin A that inhibit cell growth and induce cell differentiation in…”
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Retinoylation of cytokeratins in normal human epidermal keratinocytes by Takahashi, N, Jetten, A M, Breitman, T R

“…Retinoylation (retinoic acid acylation) is a covalent modification of proteins occurring in a variety of eukaryotic cell lines. In this study, we found that…”
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A Combination of a T Cell-Derived Lymphokine Differentiation-Inducing Activity and a Physiologic Concentration of Retinoic Acid Induces HL-60 to Differentiate to Cells With Functional Chemotactic Peptide Receptors by Imaizumi, Masue, Breitman, Theodore R.

“…The human acute promyelocytic leukemia cell line HL-60 is induced by retinoic acid (RA) and N,N-dimethylformamide (DMF) to differentiate into cells having many…”
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The covalent labeling of proteins by 17 beta-estradiol, retinoic acid, and progesterone in the human breast cancer cell lines MCF-7 and MCF-7/AdrR by Takahashi, N, Breitman, T R

“…In this study we analyzed the covalent binding to proteins of 17 beta-estradiol (E2), retinoic acid (RA), and progesterone in MCF-7 and MCF-7/AdrR cells. MCF-7…”
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Tunicamycin in combination with retinoic acid synergistically inhibits cell growth while decreasing palmitoylation and enhancing retinoylation of proteins in the human breast cancer cell line MCF-7 by Takahashi, N, Iwahori, A, Breitman, T R, Fukui, T

“…All-trans-Retinoic acid (RA) induces differentiation and inhibits growth of many tumor types. Whereas the RA nuclear receptors mediate genomic effects of RA,…”
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