Search Results - "Breitling, Johannes"
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Clinical routine acquisition protocol for 3D relaxation‐compensated APT and rNOE CEST‐MRI of the human brain at 3T
Published in Magnetic resonance in medicine (01-07-2021)“…Purpose The value of relaxation‐compensated amide proton transfer (APT) and relayed nuclear Overhauser effect (rNOE) chemical exchange saturation transfer…”
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2
A novel normalization for amide proton transfer CEST MRI to correct for fat signal–induced artifacts: application to human breast cancer imaging
Published in Magnetic resonance in medicine (01-03-2020)“…Purpose The application of amide proton transfer (APT) CEST MRI for diagnosis of breast cancer is of emerging interest. However, APT imaging in the human…”
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3
Volumetric mapping of intra‐ and extracellular pH in the human brain using 31P MRSI at 7T
Published in Magnetic resonance in medicine (01-10-2020)“…Purpose In vivo 31P MRSI enables noninvasive mapping of absolute pH values via the pH‐dependent chemical shifts of inorganic phosphates (Pi). A particular…”
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4
Mapping an Extended Metabolic Profile of Gliomas Using High-Resolution 31P MRSI at 7T
Published in Frontiers in neurology (23-12-2021)“…Phosphorus magnetic resonance spectroscopic imaging ( 31 P MRSI) is of particular interest for investigations of patients with brain tumors as it enables to…”
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31P MRSI at 7 T enables high‐resolution volumetric mapping of the intracellular magnesium ion content in human lower leg muscles
Published in Magnetic resonance in medicine (01-08-2022)“…Purpose The non‐invasive determination of the free magnesium ion concentration ([Mg2+free]) using 31P MRSI in vivo is of interest in research on various…”
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6
Adaptive denoising for chemical exchange saturation transfer MR imaging
Published in NMR in biomedicine (01-11-2019)“…High image signal–to–noise ratio (SNR) is required to reliably detect the inherently small chemical exchange saturation transfer (CEST) effects in vivo. In…”
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31 P MRSI at 7 T enables high-resolution volumetric mapping of the intracellular magnesium ion content in human lower leg muscles
Published in Magnetic resonance in medicine (01-08-2022)“…The non-invasive determination of the free magnesium ion concentration ([Mg ]) using P MRSI in vivo is of interest in research on various pathologies, e.g…”
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8
Mapping intracellular pH in tumors using amide and guanidyl CEST‐MRI at 9.4 T
Published in Magnetic resonance in medicine (01-05-2022)“…Purpose In principle, non‐invasive mapping of the intracellular pH (pHi) in vivo is possible using endogenous chemical exchange saturation transfer (CEST)‐MRI…”
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9
Early response assessment of glioma patients to definitive chemoradiotherapy using chemical exchange saturation transfer imaging at 7 T
Published in Journal of magnetic resonance imaging (01-10-2019)“…Background Patients with newly diagnosed inoperable glioma receive chemoradiotherapy (CRT). Standard Response Assessment in Neuro‐Oncology (RANO) takes a…”
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10
Relaxation‐compensated APT and rNOE CEST‐MRI of human brain tumors at 3 T
Published in Magnetic resonance in medicine (01-08-2019)“…Purpose Relaxation‐compensated CEST‐MRI (i.e., the inverse metrics magnetization transfer ratio and apparent exchange‐dependent relaxation) has already been…”
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A versatile look‐up algorithm for mapping pH values and magnesium ion content using 31P MRSI
Published in NMR in biomedicine (01-06-2024)“…31P MRSI allows for the non‐invasive mapping of pH and magnesium ion content (Mg) in vivo, by translating the chemical shifts of inorganic phosphate and…”
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12
A versatile look-up algorithm for mapping pH values and magnesium ion content using 31 P MRSI
Published in NMR in biomedicine (01-06-2024)“…P MRSI allows for the non-invasive mapping of pH and magnesium ion content (Mg) in vivo, by translating the chemical shifts of inorganic phosphate and…”
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13
Semi‐solid MT and APTw CEST‐MRI predict clinical outcome of patients with glioma early after radiotherapy
Published in Magnetic resonance in medicine (01-10-2023)“…Purpose The purpose of this study was to compare the potential of asymmetry‐based (APTwasym), Lorentzian‐fit‐based (PeakAreaAPT and MTconst), and…”
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CEST imaging of the APT and ssMT predict the overall survival of patients with glioma at the first follow-up after completion of radiotherapy at 3T
Published in Radiotherapy and oncology (01-07-2023)“…•APTw imaging after radiotherapy predicts survival of patients with glioma.•Imaging of the ssMT following radiotherapy predicts survival of patients with…”
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15
Motion correction for three‐dimensional chemical exchange saturation transfer imaging without direct water saturation artifacts
Published in NMR in biomedicine (01-07-2022)“…In chemical exchange saturation transfer (CEST) MRI, motion correction is compromised by the drastically changing image contrast at different frequency…”
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16
Volumetric mapping of intra- and extracellular pH in the human brain using 31 P MRSI at 7T
Published in Magnetic resonance in medicine (01-10-2020)“…In vivo P MRSI enables noninvasive mapping of absolute pH values via the pH-dependent chemical shifts of inorganic phosphates (P ). A particular challenge is…”
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17
Assessing the influence of the menstrual cycle on APT CEST-MRI in the human breast
Published in Magnetic resonance imaging (01-09-2022)“…In fibroglandular breast tissue, conventional dynamic contrast-enhanced MR-mammography is known to be affected by water content changes during the menstrual…”
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18
Optimized dualCEST‐MRI for imaging of endogenous bulk mobile proteins in the human brain
Published in NMR in biomedicine (01-05-2020)“…Dual‐frequency irradiation chemical exchange saturation transfer (dualCEST) allows imaging of endogenous bulk mobile proteins by selectively measuring the…”
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19
Dynamic glucose‐enhanced (DGE) MRI in the human brain at 7 T with reduced motion‐induced artifacts based on quantitative R1ρ mapping
Published in Magnetic resonance in medicine (01-07-2020)“…Purpose Dynamic glucose‐enhanced (DGE)‐MRI based on chemical exchange‐sensitive MRI, that is, glucoCEST and gluco‐chemical exchange‐sensitive…”
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Dynamic glucose-enhanced (DGE) MRI in the human brain at 7 T with reduced motion-induced artifacts based on quantitative R 1ρ mapping
Published in Magnetic resonance in medicine (01-07-2020)“…Dynamic glucose-enhanced (DGE)-MRI based on chemical exchange-sensitive MRI, that is, glucoCEST and gluco-chemical exchange-sensitive spin-lock (glucoCESL), is…”
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