Search Results - "Breitkreutz, Ashton"

The BioGRID interaction database: 2015 update by Chatr-Aryamontri, Andrew, Breitkreutz, Bobby-Joe, Oughtred, Rose, Boucher, Lorrie, Heinicke, Sven, Chen, Daici, Stark, Chris, Breitkreutz, Ashton, Kolas, Nadine, O'Donnell, Lara, Reguly, Teresa, Nixon, Julie, Ramage, Lindsay, Winter, Andrew, Sellam, Adnane, Chang, Christie, Hirschman, Jodi, Theesfeld, Chandra, Rust, Jennifer, Livstone, Michael S, Dolinski, Kara, Tyers, Mike

“…The Biological General Repository for Interaction Datasets (BioGRID: http://thebiogrid.org) is an open access database that houses genetic and protein…”
Get full text

SAINT: probabilistic scoring of affinity purification-mass spectrometry data by Gingras, Anne-Claude, Nesvizhskii, Alexey I, Choi, Hyungwon, Larsen, Brett, Lin, Zhen-Yuan, Breitkreutz, Ashton, Mellacheruvu, Dattatreya, Fermin, Damian, Qin, Zhaohui S, Tyers, Mike

“…We present 'significance analysis of interactome' (SAINT), a computational tool that assigns confidence scores to protein-protein interaction data generated…”
Get full text

The BioGRID interaction database: 2013 update by Chatr-Aryamontri, Andrew, Breitkreutz, Bobby-Joe, Heinicke, Sven, Boucher, Lorrie, Winter, Andrew, Stark, Chris, Nixon, Julie, Ramage, Lindsay, Kolas, Nadine, O'Donnell, Lara, Reguly, Teresa, Breitkreutz, Ashton, Sellam, Adnane, Chen, Daici, Chang, Christie, Rust, Jennifer, Livstone, Michael, Oughtred, Rose, Dolinski, Kara, Tyers, Mike

“…The Biological General Repository for Interaction Datasets (BioGRID: http//thebiogrid.org) is an open access archive of genetic and protein interactions that…”
Get full text

Global Protein Kinase and Phosphatase Interaction Network in Yeast by Breitkreutz, Ashton, Choi, Hyungwon, Sharom, Jeffrey R, Boucher, Lorrie, Neduva, Victor, Larsen, Brett, Lin, Zhen-Yuan, Breitkreutz, Bobby-Joe, Stark, Chris, Liu, Guomin, Ahn, Jessica, Dewar-Darch, Danielle, Reguly, Teresa, Tang, Xiaojing, Almeida, Ricardo, Qin, Zhaohui Steve, Pawson, Tony, Gingras, Anne-Claude, Nesvizhskii, Alexey I, Tyers, Mike

“…The interactions of protein kinases and phosphatases with their regulatory subunits and substrates underpin cellular regulation. We identified a kinase and…”
Get full text

Type III secretion effectors of the IpaH family are E3 ubiquitin ligases by Rohde, John R, Breitkreutz, Ashton, Chenal, Alexandre, Sansonetti, Philippe J, Parsot, Claude

“…Many bacteria pathogenic for plants or animals, including Shigella spp., which is responsible for shigellosis in humans, use a type III secretion apparatus to…”
Get full text

ProHits: integrated software for mass spectrometry-based interaction proteomics by Tyers, Mike, Gingras, Anne-Claude, Liu, Guomin, Zhang, Jianping, Larsen, Brett, Stark, Chris, Breitkreutz, Ashton, Lin, Zhen-Yuan, Breitkreutz, Bobby-Joe, Ding, Yongmei, Colwill, Karen, Pasculescu, Adrian, Pawson, Tony, Wrana, Jeffrey L, Nesvizhskii, Alexey I, Raught, Brian

Get full text

Global analysis of protein phosphorylation in yeast by Ptacek, J, Devgan, G, Michaud, G, Zhu, H, Zhu, X, Fasolo, J, Guo, H, Jona, G, Breitkreutz, A, Sopko, R

“…Protein phosphorylation is estimated to affect 30% of the proteome and is a major regulatory mechanism that controls many basic cellular processes. Until…”
Get full text

Stratus not altocumulus: a new view of the yeast protein interaction network by Batada, Nizar N, Reguly, Teresa, Breitkreutz, Ashton, Boucher, Lorrie, Breitkreutz, Bobby-Joe, Hurst, Laurence D, Tyers, Mike

“…Systems biology approaches can reveal intermediary levels of organization between genotype and phenotype that often underlie biological phenomena such as…”
Get full text

Still stratus not altocumulus: further evidence against the date/party hub distinction by Batada, Nizar N, Reguly, Teresa, Breitkreutz, Ashton, Boucher, Lorrie, Breitkreutz, Bobby-Joe, Hurst, Laurence D, Tyers, Mike

“…In particular, when controlling for important covariables where necessary, there is no evidence for (1) bimodality in partner co-expression, (2) enrichment for…”
Get full text

MAPK specificity in the yeast pheromone response independent of transcriptional activation by Breitkreutz, Ashton, Boucher, Lorrie, Tyers, Mike

“…The mechanisms whereby different external cues stimulate the same mitogen-activated protein kinase (MAPK) cascade, yet trigger an appropriately distinct…”
Get full text

Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae by Reguly, Teresa, Breitkreutz, Ashton, Boucher, Lorrie, Breitkreutz, Bobby-Joe, Hon, Gary C, Myers, Chad L, Parsons, Ainslie, Friesen, Helena, Oughtred, Rose, Tong, Amy, Stark, Chris, Ho, Yuen, Botstein, David, Andrews, Brenda, Boone, Charles, Troyanskya, Olga G, Ideker, Trey, Dolinski, Kara, Batada, Nizar N, Tyers, Mike

“…The study of complex biological networks and prediction of gene function has been enabled by high-throughput (HTP) methods for detection of genetic and protein…”
Get full text

BioGRID: a general repository for interaction datasets by Stark, Chris, Breitkreutz, Bobby-Joe, Reguly, Teresa, Boucher, Lorrie, Breitkreutz, Ashton, Tyers, Mike

“…Access to unified datasets of protein and genetic interactions is critical for interrogation of gene/protein function and analysis of global network…”
Get full text

BioGRID Interaction Database: 2008 update by Breitkreutz, Bobby-Joe, Stark, Chris, Reguly, Teresa, Boucher, Lorrie, Breitkreutz, Ashton, Livstone, Michael, Oughtred, Rose, Lackner, Daniel H, Bähler, Jürg, Wood, Valerie, Dolinski, Kara, Tyers, Mike

“…The Biological General Repository for Interaction Datasets (BioGRID) database (http://www.thebiogrid.org) was developed to house and distribute collections of…”
Get full text

A Sophisticated Scaffold Wields a New Trick by Breitkreutz, Ashton, Tyers, Mike

“…Many cellular processes are governed by proteins that are docked onto a scaffold protein. In addition to providing binding sites, scaffolds influence the…”
Get full text

BioGRID: A Resource for Studying Biological Interactions in Yeast by Oughtred, Rose, Chatr-aryamontri, Andrew, Breitkreutz, Bobby-Joe, Chang, Christie S, Rust, Jennifer M, Theesfeld, Chandra L, Heinicke, Sven, Breitkreutz, Ashton, Chen, Daici, Hirschman, Jodi, Kolas, Nadine, Livstone, Michael S, Nixon, Julie, O'Donnell, Lara, Ramage, Lindsay, Winter, Andrew, Reguly, Teresa, Sellam, Adnane, Stark, Chris, Boucher, Lorrie, Dolinski, Kara, Tyers, Mike

“…The Biological General Repository for Interaction Datasets (BioGRID) is a freely available public database that provides the biological and biomedical research…”
Get more information

Characterization of the Basal and Pheromone‐Stimulated Phosphorylation States of Ste12p by Hung, Wesley, Olson, K. Amy, Breitkreutz, Ashton, Sadowski, Ivan

“…The Saccharomyces cerevisiae transcription factor Ste12p is required for basal and activated expression of pheromone‐responsive genes, and for invasive growth…”
Get full text

PhosphoGRID: a database of experimentally verified in vivo protein phosphorylation sites from the budding yeast Saccharomyces cerevisiae by Stark, Chris, Su, Ting-Cheng, Breitkreutz, Ashton, Lourenco, Pedro, Dahabieh, Matthew, Breitkreutz, Bobby-Joe, Tyers, Mike, Sadowski, Ivan

“…Protein phosphorylation plays a central role in cellular regulation. Recent proteomics strategies for identifying phosphopeptides have been developed using the…”
Get full text

Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions by Oughtred, Rose, Chatr-aryamontri, Andrew, Breitkreutz, Bobby-Joe, Chang, Christie S, Rust, Jennifer M, Theesfeld, Chandra L, Heinicke, Sven, Breitkreutz, Ashton, Chen, Daici, Hirschman, Jodi, Kolas, Nadine, Livstone, Michael S, Nixon, Julie, O'Donnell, Lara, Ramage, Lindsay, Winter, Andrew, Reguly, Teresa, Sellam, Adnane, Stark, Chris, Boucher, Lorrie, Dolinski, Kara, Tyers, Mike

“…The BioGRID database is an extensive repository of curated genetic and protein interactions for the budding yeast Saccharomyces cerevisiae, the fission yeast…”
Get more information

MAPK signaling specificity: it takes two to tango by Breitkreutz, Ashton, Tyers, Mike

“…A surprisingly limited repertoire of core signaling pathways generates an enormous diversity of responses, often in a cell type-specific manner. Even within…”
Get full text

Cell signaling. A sophisticated scaffold wields a new trick by Breitkreutz, Ashton, Tyers, Mike

“…A complex and dynamic network of signaling proteins enables eukaryotic cells to respond to different stimuli, including changes in their physical environment,…”
Get full text