Search Results - "Breitbart, Roger E."

Longitudinal Outcomes of Patients With Single Ventricle After the Fontan Procedure by Atz, Andrew M., MD, Zak, Victor, PhD, Mahony, Lynn, MD, Uzark, Karen, PhD, D’agincourt, Nicholas, MS, Goldberg, David J., MD, Williams, Richard V., MD, Breitbart, Roger E., MD, Colan, Steven D., MD, Burns, Kristin M., MD, Margossian, Renee, MD, Henderson, Heather T., MD, Korsin, Rosalind, RN, Marino, Bradley S., MD, Daniels, Kaitlyn, RN, McCrindle, Brian W., MD, MPH

“…Abstract Background Multicenter longitudinal objective data for survival into adulthood of patients who have undergone Fontan procedures are lacking…”
Get full text

Parent and Physician Understanding of Prognosis in Hospitalized Children With Advanced Heart Disease by Morell, Emily, Miller, Mary Katherine, Lu, Minmin, Friedman, Kevin G, Breitbart, Roger E, Reichman, Jeffrey R, McDermott, Julie, Sleeper, Lynn A, Blume, Elizabeth D

“…Background The unpredictable trajectory of pediatric advanced heart disease makes prognostication difficult for physicians and informed decision-making…”
Get full text

Value of Troponin Testing for Detection of Heart Disease in Previously Healthy Children by Dionne, Audrey, Kheir, John N, Sleeper, Lynn A, Esch, Jesse J, Breitbart, Roger E

“…Background Troponin levels are frequently obtained in pediatric patients, but the benefit remains unclear. Methods and Results This retrospective study…”
Get full text

Late Status of Fontan Patients With Persistent Surgical Fenestration by Atz, Andrew M., MD, Travison, Thomas G., PhD, McCrindle, Brian W., MD, MPH, Mahony, Lynn, MD, Quartermain, Michael, MD, Williams, Richard V., MD, Breitbart, Roger E., MD, Lu, Minmin, MS, Radojewski, Elizabeth, RN, Margossian, Renee, MD, Covitz, Wesley, MD, Gersony, Welton M., MD

“…Objectives This study was undertaken to determine the effects of creating a systemic-to-pulmonary venous atrial-level communication (fenestration) at the time…”
Get full text

A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9 by Donoghue, Mary, Hsieh, Frank, Baronas, Elizabeth, Godbout, Kevin, Gosselin, Michael, Stagliano, Nancy, Donovan, Michael, Woolf, Betty, Robison, Keith, Jeyaseelan, Raju, Breitbart, Roger E, Acton, Susan

“…ACE2, the first known human homologue of angiotensin-converting enzyme (ACE), was identified from 5′ sequencing of a human heart failure ventricle cDNA…”
Get full text

Multiphysiologic State Computational Fluid Dynamics Modeling for Planning Fontan With Interrupted Inferior Vena Cava by Hoganson, David M., Govindarajan, Vijay, Schulz, Noah E., Eickhoff, Emily R., Breitbart, Roger E., Marx, Gerald R., del Nido, Pedro J., Hammer, Peter E.

“…Single ventricle (SV) patients with interrupted inferior vena cava (iIVC) and azygos continuation are at high risk for unbalanced hepatic venous flow (HVF)…”
Get full text

Functional status, heart rate, and rhythm abnormalities in 521 Fontan patients 6 to 18 years of age by Blaufox, Andrew D., MD, Sleeper, Lynn A., ScD, Bradley, David J., MD, Breitbart, Roger E., MD, Hordof, Allan, MD, Kanter, Ronald J., MD, Stephenson, Elizabeth A., MD, Stylianou, Mario, PhD, Vetter, Victoria L., MD, Saul, J. Philip, MD

“…Objectives Our objective was to determine the relationship between functional outcome and abnormalities of heart rate and rhythm after the Fontan operation…”
Get full text

Toxocara Myopericarditis and Cardiac Magnetic Resonance Imaging in a Young Girl by Gearhart, Addison, Savage, Timothy J., Sandora, Thomas J., Lamb, Gabriella S., Powell, Andrew J., Breitbart, Roger E.

“…Cardiac infection with Toxocara is rarely diagnosed, especially in children, and corresponding cardiac magnetic resonance imaging (CMR) has not been reported…”
Get full text

The Fontan Patient: Inconsistencies in Medication Therapy Across Seven Pediatric Heart Network Centers by Anderson, Page A. W., Breitbart, Roger E., McCrindle, Brian W., Sleeper, Lynn A., Atz, Andrew M., Hsu, Daphne T., Lu, Minmin, Margossian, Renee, Williams, Richard V.

“…Patients who have undergone the Fontan procedure are at risk for thrombosis, ventricular dysfunction, and valve regurgitation, but data to guide the medical…”
Get full text

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies by Homsy, Jason, Zaidi, Samir, Shen, Yufeng, Ware, James S., Samocha, Kaitlin E., Karczewski, Konrad J., DePalma, Steven R., McKean, David, Wakimoto, Hiroko, Gorham, Josh, Jin, Sheng Chih, Deanfield, John, Giardini, Alessandro, Porter, George A., Kim, Richard, Bilguvar, Kaya, López-Giráldez, Francesc, Tikhonova, Irina, Mane, Shrikant, Romano-Adesman, Angela, Qi, Hongjian, Vardarajan, Badri, Ma, Lijiang, Daly, Mark, Roberts, Amy E., Russell, Mark W., Mital, Seema, Newburger, Jane W., Gaynor, J. William, Breitbart, Roger E., Iossifov, Ivan, Ronemus, Michael, Sanders, Stephan J., Kaltman, Jonathan R., Seidman, Jonathan G., Brueckner, Martina, Gelb, Bruce D., Goldmuntz, Elizabeth, Lifton, Richard P., Seidman, Christine E., Chung, Wendy K.

“…Congenital heart disease (CHD) patients have an increased prevalence of extracardiac congenital anomalies (CAs) and risk of neurodevelopmental disabilities…”
Get full text

De novo mutations in histone-modifying genes in congenital heart disease by Zaidi, Samir, Choi, Murim, Wakimoto, Hiroko, Ma, Lijiang, Jiang, Jianming, Overton, John D., Romano-Adesman, Angela, Bjornson, Robert D., Breitbart, Roger E., Brown, Kerry K., Carriero, Nicholas J., Cheung, Yee Him, Deanfield, John, DePalma, Steve, Fakhro, Khalid A., Glessner, Joseph, Hakonarson, Hakon, Italia, Michael J., Kaltman, Jonathan R., Kaski, Juan, Kim, Richard, Kline, Jennie K., Lee, Teresa, Leipzig, Jeremy, Lopez, Alexander, Mane, Shrikant M., Mitchell, Laura E., Newburger, Jane W., Parfenov, Michael, Pe’er, Itsik, Porter, George, Roberts, Amy E., Sachidanandam, Ravi, Sanders, Stephan J., Seiden, Howard S., State, Mathew W., Subramanian, Sailakshmi, Tikhonova, Irina R., Wang, Wei, Warburton, Dorothy, White, Peter S., Williams, Ismee A., Zhao, Hongyu, Seidman, Jonathan G., Brueckner, Martina, Chung, Wendy K., Gelb, Bruce D., Goldmuntz, Elizabeth, Seidman, Christine E., Lifton, Richard P.

“…Exome sequencing of patients with congenital heart disease (CHD) and their unaffected parents reveals an excess of strong-effect, protein-altering de novo…”
Get full text

Factors associated with morbidity, mortality, and hemodynamic failure after biventricular conversion in borderline hypoplastic left hearts by Beattie, Meaghan J, Sleeper, Lynn A, Lu, Minmin, Teele, Sarah A, Breitbart, Roger E, Esch, Jesse J, Salvin, Joshua W, Kapoor, Urvi, Oladunjoye, Olubunmi, Emani, Sitaram M, Banka, Puja

“…A subset of patients with borderline hypoplastic left heart may be candidates for single to biventricular conversion, but long-term morbidity and mortality…”
Get full text

Staged ventricular recruitment in patients with borderline ventricles and large ventricular septal defects by Oladunjoye, Olubunmi O., Piekarski, Breanna, Banka, Puja, Marx, Gerald, Breitbart, Roger E., del Nido, Pedro J., Emani, Sitaram M.

“…Patients with borderline ventricles and ventricular septal defects (VSDs) who have previously undergone single ventricle palliation might be candidates for…”
Get full text

Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter study by Anderson, Page A W, Sleeper, Lynn A, Mahony, Lynn, Colan, Steven D, Atz, Andrew M, Breitbart, Roger E, Gersony, Welton M, Gallagher, Dianne, Geva, Tal, Margossian, Renee, McCrindle, Brian W, Paridon, Stephen, Schwartz, Marcy, Stylianou, Mario, Williams, Richard V, Clark, 3rd, Bernard J

“…We characterized a large cohort of children who had a Fontan procedure, with measures of functional health status, ventricular size and function, exercise…”
Get full text

Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice by Gurley, Susan B, Allred, Alicia, Le, Thu H, Griffiths, Robert, Mao, Lan, Philip, Nisha, Haystead, Timothy A, Donoghue, Mary, Breitbart, Roger E, Acton, Susan L, Rockman, Howard A, Coffman, Thomas M

“…The carboxypeptidase ACE2 is a homologue of angiotensin-converting enzyme (ACE). To clarify the physiological roles of ACE2, we generated mice with targeted…”
Get full text

Transient elastography may identify Fontan patients with unfavorable hemodynamics and advanced hepatic fibrosis by Wu, Fred M, Opotowsky, Alexander R, Raza, Roshan, Harney, Sarah, Ukomadu, Chinweike, Landzberg, Michael J, Valente, Anne M, Breitbart, Roger E, Singh, Michael N, Gauvreau, Kimberlee, Jonas, Maureen M

“…Transient elastography (TE) offers a noninvasive correlate with the degree of hepatic fibrosis. However, factors other than fibrosis affect liver stiffness. We…”
Get more information

Contemporary Outcomes After the Fontan Procedure by Anderson, Page A.W., MD, Sleeper, Lynn A., ScD, Mahony, Lynn, MD, Colan, Steven D., MD, Atz, Andrew M., MD, Breitbart, Roger E., MD, Gersony, Welton M., MD, Gallagher, Dianne, MS, Geva, Tal, MD, Margossian, Renee, MD, McCrindle, Brian W., MD, MPH, Paridon, Stephen, MD, Schwartz, Marcy, MD, Stylianou, Mario, PhD, Williams, Richard V., MD, Clark, Bernard J., MD

“…Contemporary Outcomes After the Fontan Procedure: A Pediatric Heart Network Multicenter Study Page A. W. Anderson, Lynn A. Sleeper, Lynn Mahony, Steven D…”
Get full text

Truncus arteriosus versus tetralogy of Fallot with pulmonary atresia by Greenhouse, David G, Breitbart, Roger E, Baird, Christopher W

“…Truncus arteriosus and tetralogy of Fallot with pulmonary atresia may be difficult to differentiate prenatally. We present a case that, on newborn…”
Get more information

Survival data and predictors of functional outcome an average of 15 years after the Fontan procedure: the pediatric heart network Fontan cohort by Atz, Andrew M, Zak, Victor, Mahony, Lynn, Uzark, Karen, Shrader, Peter, Gallagher, Dianne, Paridon, Stephen M, Williams, Richard V, Breitbart, Roger E, Colan, Steven D, Kaltman, Jonathan R, Margossian, Renee, Pasquali, Sara K, Allen, Kerstin, Lai, Wyman W, Korsin, Rosalind, Marino, Bradley S, Mirarchi, Nicole, McCrindle, Brian W

“…Multicenter longitudinal outcome data for Fontan patients surviving into adulthood are lacking. The aim of this study was to better understand contemporary…”
Get more information

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot by Seidman, Christine E, Greenway, Steven C, Pereira, Alexandre C, Lin, Jennifer C, DePalma, Steven R, Israel, Samuel J, Mesquita, Sonia M, Ergul, Emel, Conta, Jessie H, Korn, Joshua M, McCarroll, Steven A, Gorham, Joshua M, Gabriel, Stacey, Altshuler, David M, de Lourdes Quintanilla-Dieck, Maria, Artunduaga, Maria Alexandra, Eavey, Roland D, Plenge, Robert M, Shadick, Nancy A, Weinblatt, Michael E, De Jager, Philip L, Hafler, David A, Breitbart, Roger E, Seidman, Jonathan G

“…Tetralogy of Fallot (TOF), the most common severe congenital heart malformation, occurs sporadically, without other anomaly, and from unknown cause in 70% of…”
Get full text