Search Results - "Breining, Dorit"

Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells by Göbel, Andy, Breining, Dorit, Rauner, Martina, Hofbauer, Lorenz C., Rachner, Tilman D.

“…The mevalonate pathway has emerged as a promising target for several solid tumors. Statins are inhibitors of the 3-hydroxy-3-methylglutaryl-CoA reductase…”
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High serum levels of periostin are associated with a poor survival in breast cancer by Rachner, Tilman D., Göbel, Andy, Hoffmann, Oliver, Erdmann, Kati, Kasimir-Bauer, Sabine, Breining, Dorit, Kimmig, Rainer, Hofbauer, Lorenz C., Bittner, Ann-Kathrin

“…Purpose Periostin is a secreted extracellular matrix protein, which was originally described in osteoblasts. It supports osteoblastic differentiation and bone…”
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Plasma levels of Semaphorin 4D are decreased by adjuvant tamoxifen but not aromatase inhibitor therapy in breast cancer patients by Göbel, Andy, Kuhlmann, Jan D., Link, Theresa, Wimberger, Pauline, Link-Rachner, Cornelia, Thiele, Stefanie, Dell'Endice, Stefania, Furesi, Giulia, Breining, Dorit, Rauner, Martina, Hofbauer, Lorenz C., Rachner, Tilman D.

“…Semaphorin 4D (Sema4D) is a glycoprotein that inhibits bone formation and has been associated with cancer progression and the occurrence of bone metastases…”
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Overcoming statin resistance in prostate cancer cells by targeting the 3-hydroxy-3-methylglutaryl-CoA-reductase by Göbel, Andy, Pählig, Sophie, Motz, Anja, Breining, Dorit, Traikov, Sofia, Hofbauer, Lorenz C., Rachner, Tilman D.

“…Prostate cancer is the most prevalent malignancy in men. While diagnostic and therapeutic interventions have substantially improved in recent years, disease…”
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Small-molecule CBP/p300 histone acetyltransferase inhibition mobilizes leukocytes from the bone marrow via the endocrine stress response by Jaschke, Nikolai P, Breining, Dorit, Hofmann, Maura, Pählig, Sophie, Baschant, Ulrike, Oertel, Reinhard, Traikov, Sofia, Grinenko, Tatyana, Saettini, Francesco, Biondi, Andrea, Stylianou, Myrto, Bringmann, Henrik, Zhang, Cuiling, Yoshida, Tomomi M, Weidner, Heike, Poller, Wolfram C, Swirski, Filip K, Göbel, Andy, Hofbauer, Lorenz C, Rauner, Martina, Scheiermann, Christoph, Wang, Andrew, Rachner, Tilman D

“…Mutations of the CBP/p300 histone acetyltransferase (HAT) domain can be linked to leukemic transformation in humans, suggestive of a checkpoint of leukocyte…”
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