Search Results - "Breider, Mike A"

Discovery of Highly Potent and Selective Pan-Aurora Kinase Inhibitors with Enhanced in Vivo Antitumor Therapeutic Index by Liu, Gang, Abraham, Sunny, Tran, Lan, Vickers, Troy D, Xu, Shimin, Hadd, Michael J, Quiambao, Sheena, Holladay, Mark W, Hua, Helen, Ford Pulido, Julia M, Gunawardane, Ruwanthi N, Davis, Mindy I, Eichelberger, Shawn R, Apuy, Julius L, Gitnick, Dana, Gardner, Michael F, James, Joyce, Breider, Mike A, Belli, Barbara, Armstrong, Robert C, Treiber, Daniel K

“…Serine/threonine protein kinases Aurora A, B, and C play essential roles in cell mitosis and cytokinesis. Currently a number of Aurora kinase inhibitors with…”
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Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases by Liu, Gang, Campbell, Brian T, Holladay, Mark W, Ford Pulido, Julia M, Hua, Helen, Gitnick, Dana, Gardner, Michael F, James, Joyce, Breider, Mike A, Brigham, Daniel, Belli, Barbara, Armstrong, Robert C, Treiber, Daniel K

“…A series of potent, selective platelet-derived growth factor receptor-family kinase inhibitors was optimized starting from a globally selective lead molecule 4…”
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Retinal degeneration in rats induced by CI-1010, a 2-nitroimidazole radiosensitizer by Breider, M A, Pilcher, G D, Graziano, M J, Gough, A W

“…The anti-cancer compound CI-1010, designated as (R)-alpha-([(2-bromoethyl)amino]methyl)-2-nitro-1H-imidazole-1-ethanol monohydrobromide, has a proposed dual…”
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Tumor necrosis factor alpha and interleukin 1 alpha enhance lipopolysaccharide-mediated bovine endothelial cell injury by Sharma, S A, Olchowy, T W, Yang, Z, Breider, M A

“…Alveolar macrophages (AMs) are important in the host response to aerogenous pulmonary bacterial infections, such as Pasteurella haemolytica-induced pneumonia…”
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Tumor cell-enhanced sensitivity of vascular endothelial cells to photodynamic therapy by Yang, Z, Lu, X, Frazier, D L, Panjehpour, M, Breider, M A

“…Effective antitumor photodynamic therapy (PDT) may be related to damage of vasculature within the tumor. The purpose of this study was to determine if tumor…”
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Endothelium and inflammation by Breider, M A

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Nitro-imidazole radiosensitizer-induced toxicity in cynomolgus monkeys by Breider, M A, Ulloa, H M, Pegg, D G, Gough, A W

“…Intravenously administered nitro-imidazole radiosensitizer and alkylating anticancer compound CI-1010, designated as…”
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Alveolar Macrophage and Neutrophil Interactions in Pasteurella haemolytica-Induced Endothelial Cell Injury by Sharma, Smita A., Olchowy, T. W.J., Breider, Mike A.

“…Pasteurella haemolytica, the cause of fibrinous pleuropneumonia in cattle, produces extensive microvascular endothelial cell damage. This study investigated…”
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Cytokine modulation of endothelial cell sensitivity to photodynamic therapy by Breider, M A, Lu, X, Panjehpour, M, Frazier, D L

“…The purpose of this study was to determine if recombinant angiogenic cytokines modulate the sensitivity of endothelial cells to the toxic effects of…”
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Effect of Pasteurella haemolytica saline capsular extract on bovine pulmonary endothelial cells by Kumar, S, Breider, M A, Corstvet, R E, Maddux, J L

“…The purpose of this in vitro study was to determine whether Pasteurella haemolytica capsular extract (CE) damages bovine pulmonary endothelial cells (EC)…”
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Detection of Ehrlichia risticii using an avidin-biotin-immunoperoxidase staining system by Breider, M A, Callahan, G, Corstvet, R E

“…An indirect immunoperoxidase procedure using a specific anti-Ehrlichia risticii monoclonal antibody and an avidin-biotin-peroxidase staining method was used to…”
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