Search Results - "Brehm, B. R"
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Extra cellular matrix remodelling after heterotopic rat heart transplantation: gene expression profiling and involvement of ED-A⁺ fibronectin, alpha-smooth muscle actin and B⁺ tenascin-C in chronic cardiac allograft rejection
Published in Histochemistry and cell biology (01-11-2010)“…Chronic cardiac rejection is represented by cardiac allograft vasculopathy (CAV) and cardiac interstitial fibrosis (CIF) known to cause severe complications…”
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2
Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells
Published in Cardiovascular research (01-02-2001)“…Secondary failure due to late restenosis continues to occur in 30-50% of individuals after PTCA. beta-Blockers play an important role in the treatment of CAD…”
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3
Paclitaxel inhibits arterial smooth muscle cell proliferation and migration in vitro and in vivo using local drug delivery
Published in Circulation (New York, N.Y.) (15-07-1997)“…The antineoplastic compound paclitaxel (Taxol) causes an increased assembly of extraordinarily stable microtubules. The present study was designed to…”
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4
Early outcome of carotid angioplasty and stenting with and without cerebral protection devices: A systematic review of the literature
Published in Stroke (1970) (01-03-2003)“…Carotid angioplasty and stenting (CAS) is increasingly being used for treatment of symptomatic and asymptomatic carotid artery disease (CAD). To evaluate the…”
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5
Influence of growth factors on the proliferation of vascular smooth muscle cells isolated from subtotally nephrectomized rats after endothelin or angiotensin II antagonism
Published in Nephrology, dialysis, transplantation (01-02-2005)“…Background. Cardiovascular disease is the most important cause of death in patients with end-stage renal disease. In uraemia, the renin–angiotensin–aldosterone…”
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6
Chlamydia pneumoniae IgA seropositivity is associated with increased risk for atherosclerotic vascular disease, myocardial infarction and stroke in dialysis patients
Published in Clinical nephrology (01-04-2003)“…Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in patients with chronic renal failure undergoing dialysis therapy. Aim of…”
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7
Endothelin-1 and Endothelin-3 Levels in Different Types of Glomerulonephritis
Published in Journal of cardiovascular pharmacology (1998)“…There is evidence that an activated renal endothelin (ET) system is involved in development of glomerulosclerosis. However it is still unknown if different ETs…”
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Downregulation of β-adrenergic receptors by low density lipoproteins and its prevention by β-adrenergic receptor antagonists
Published in Cardiovascular research (01-05-1998)“…Vasodilation by beta-adrenergic receptors of smooth muscle cells appears to be impaired early after the onset of hypercholesteremia. The aim of this study was…”
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9
Dynamic Regulation of β-Adrenergic Receptors by Endothelin-1 in Smooth-Muscle Cells
Published in Journal of cardiovascular pharmacology (1998)“…Elevated endothelin-1 (ET-1) levels are found in atherosclerosis, myocardial ischemia, and heart failure, and are correlated with increased mortality rates…”
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10
Comparison of Circulating Endothelin-1 and Big Endothelin-1 Levels in Unstable Versus Stable Angina Pectoris
Published in Journal of cardiovascular pharmacology (1998)“…The pathophysiologic meaning of elevated circulating endothelin-1 (ET-1) levels in various cardiovascular diseases is not understood. The aim of this study was…”
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11
β-Blockers of the Third Generation Inhibit Endothelin-1 Liberation, mRNA Production and Proliferation of Human Coronary Smooth Muscle and Endothelial Cells
Published in Journal of cardiovascular pharmacology (2000)“…Endothelin-1 (ET-1) plays an important role in atherogenesis. The aim of the study reported here was to investigate the effects of the third generation…”
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12
Protective effects of endothelin antagonists in chronic renal failure
Published in Nephrology, dialysis, transplantation (1999)“…The present study suggests that ET-1 is involved in the pathogenesis of uraemic cardiac hypertrophy and in the progression of renal failure in rats with…”
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13
Prevention of human smooth muscle cell proliferation without induction of apoptosis by the topoisomerase I inhibitor topotecan
Published in Biochemical pharmacology (2001)“…Despite significant improvements in the treatment of atherosclerotic disease involving procedures such as angioplasty, bypass grafting, endartherectomy, or…”
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14
Endothelin-Receptor Antagonists in Uremic Cardiomyopathy
Published in Journal of cardiovascular pharmacology (2000)“…Increased endothelin-1 (ET-1) levels were found in patients with chronic renal failure. These correlate with the severity of renal failure. Patients with…”
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15
Chronically Elevated Endothelin-1 Concentrations Modulate the β-Adrenergic Receptor System In Vitro and In Vivo
Published in Journal of cardiovascular pharmacology (2000)“…In atherosclerosis and heart failure chronically elevated endothelin-1 (ET-1) plasma concentrations have been found which correlate with an increased…”
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Induction of cell-rich and lipid-rich plaques in a transfilter coculture system with human vascular cells
Published in Journal of vascular research (01-07-1996)“…Cell-to-cell interactions are mainly involved in the control of the proliferation, migration, differentiation and function of different cell types in a wide…”
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Hemodynamic and Inotropic Effects of the Endothelin A Antagonist BQ-610 In Vivo
Published in Journal of cardiovascular pharmacology (1998)“…The positive inotropy of endothelin-1 (ET-1) described by in vitro studies is not detectable in vivo because this effect is antagonized by cardiodepressive…”
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18
Recurrent transient ischaemic attacks in a patient with pansinusitis
Published in Der Internist (Berlin) (01-11-2006)“…A 31-year-old woman presented with neurological deficits after an operation for sinusitis. The cranial MRI revealed multiple ischaemic lesions. Laboratory…”
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Perforation of the left ventricle due to an abscess of a left ventricular thrombus: survival of the patient with a conservative medical therapy strategy
Published in BMJ case reports (13-04-2011)“…A 73-year-old male was admitted due to sepsis with fever up to 40°C after haemorrhoidectomy. Blood cultures identified Staphylococcus haemolyticus. In 1986 he…”
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20
Association of waist circumference, traditional cardiovascular risk factors, and stromal-derived factor-1 in adolescents
Published in Pediatric diabetes (01-08-2009)“…Background: Overweight and the metabolic syndrome (MS) represent dramatically increasing problems in children and adolescents. Waist circumference (WC) is an…”
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