Search Results - "Breemen, Richard B. Van"

Analysis of age-related changes in psychosine metabolism in the human brain by Marshall, Michael S, Jakubauskas, Benas, Bogue, Wil, Stoskute, Monika, Hauck, Zane, Rue, Emily, Nichols, Matthew, DiAntonio, Lisa L, van Breemen, Richard B, Kordower, Jeffrey H, Saavedra-Matiz, Carlos A, Bongarzone, Ernesto R

“…α-Synuclein aggregation has been linked to Gaucher's disease (GD) and Krabbe's disease (KD), lysosomal conditions affecting glycosphingolipid metabolism…”
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Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries by Smith, Dallas J, Bi, Huichang, Hamman, Josias, Ma, Xiaochao, Mitchell, Constance, Nyirenda, Kumbukani, Monera-Penduka, Tsitsi, Oketch-Rabah, Hellen, Paine, Mary F, Pettit, Syril, Pheiffer, Wihan, Van Breemen, Richard B, Embry, Michelle

“…The COVID-19 pandemic sparked the development of novel anti-viral drugs that have shown to be effective in reducing both fatality and hospitalization rates in…”
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Effects of Lycopene on Protein Expression in Human Primary Prostatic Epithelial Cells by XI QIU, YANG YUAN, VAISHNAV, Avani, TESSEL, Michael A, NONN, Larisa, BREEMEN, Richard B. Van

“…Clinical trials and animal studies have suggested that lycopene, the red carotenoid found in tomatoes, might be useful for the prevention of prostate cancer in…”
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Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry by Rue, Emily A., Rush, Michael D., van Breemen, Richard B.

“…Procyanidins are polyphenols abundant in dietary fruits, vegetables, nuts, legumes, and grains with a variety of chemopreventive biological effects. Rapid…”
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Cannabinoids Block Cellular Entry of SARS-CoV‑2 and the Emerging Variants by van Breemen, Richard B, Muchiri, Ruth N, Bates, Timothy A, Weinstein, Jules B, Leier, Hans C, Farley, Scotland, Tafesse, Fikadu G

“…As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2…”
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Antiviral activities of hemp cannabinoids by van Breemen, Richard B, Simchuk, Daniel

“…Hemp is an understudied source of pharmacologically active compounds and many unique plant secondary metabolites including more than 100 cannabinoids. After…”
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Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS by Li, Guannan, Nikolic, Dejan, van Breemen, Richard B

“…Defined as the roots and underground stems of principally three Glycyrrhiza species, Glycyrrhiza glabra L., Glycyrrhiza uralensis Fish. ex DC., and Glycyrrhiza…”
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Development of Safe and Effective Botanical Dietary Supplements by van Breemen, Richard B

“…Regulated differently than drugs or foods, the market for botanical dietary supplements continues to grow worldwide. The recently implemented U.S. FDA…”
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Affinity selection–mass spectrometry for the discovery of pharmacologically active compounds from combinatorial libraries and natural products by Muchiri, Ruth N., Breemen, Richard B.

“…Invented to address the high‐throughput screening (HTS) demands of combinatorial chemistry, affinity selection–mass spectrometry (AS‐MS) utilizes binding…”
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Multitargeted therapy of cancer by lycopene by van Breemen, Richard B, Pajkovic, Natasa

“…Abstract Lycopene (ψ,ψ-carotene) is the most abundant carotenoid in tomatoes and is the red pigment of not only tomatoes but also rosehips, watermelon, papaya,…”
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Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry by Huang, Lingyi, Nikolic, Dejan, van Breemen, Richard B.

“…The metabolism of the chemoprevention agent licochalcone A, which is a chemopreventive chalcone found in abundance in the licorice species Glycyrrhiza inflata…”
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Ensuring the safety of botanical dietary supplements by van Breemen, Richard B, Fong, Harry HS, Farnsworth, Norman R

“…Botanical dietary supplements with a history of safe human use may not require the same level of toxicity testing as synthetic pharmaceutical drugs. Most of…”
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Modification of Keap1 Cysteine Residues by Sulforaphane by Hu, Chenqi, Eggler, Aimee L, Mesecar, Andrew D, van Breemen, Richard B

“…Activation of the transcription factor NF-E2-related factor-2 (Nrf2) through modification of Kelch-like ECH-associated protein 1 (Keap1) cysteines, leading to…”
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Atmospheric pressure chemical ionization tandem mass spectrometry of carotenoids by van Breemen, Richard B., Dong, Linlin, Pajkovic, Natasa D.

“…[Display omitted] ► Carotenoids form [M+H]+ and M− during positive and negative ion APCI, respectively. ► Positive and negative ion APCI MS/MS provide…”
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Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’ binding pose by Vaidya, Aditya Sudheer, Neelarapu, Raghupathi, Madriaga, Antonett, Bai, He, Mendonca, Emma, Abdelkarim, Hazem, van Breemen, Richard B., Blond, Sylvie Y., Petukhov, Pavel A.

“…A novel series of HDAC8 inhibitors without a zinc-chelating hydroxamic acid moiety is reported. Photoaffinity labeling and molecular modeling studies suggest…”
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High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions by Li, Guannan, Huang, Ke, Nikolic, Dejan, van Breemen, Richard B

“…Detection of drug-drug interactions is essential during the early stages of drug discovery and development, and the understanding of drug-botanical…”
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Pharmacokinetics of a Single Dose of Turmeric Curcuminoids Depends on Formulation: Results of a Human Crossover Study by Fança-Berthon, Pascale, Tenon, Mathieu, Bouter-Banon, Sabrina Le, Manfré, Alexis, Maudet, Corinne, Dion, Angelina, Chevallier, Hélène, Laval, Julie, van Breemen, Richard B

“…Curcuminoids from turmeric rhizome have significant health benefits but low bioavailability. To assess the pharmacokinetics of a novel natural turmeric dried…”
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Prostate Cancer Risk and DNA Methylation Signatures in Aging Rats following Developmental BPA Exposure: A Dose-Response Analysis by Prins, Gail S, Ye, Shu-Hua, Birch, Lynn, Zhang, Xiang, Cheong, Ana, Lin, Han, Calderon-Gierszal, Esther, Groen, Jacob, Hu, Wen-Yang, Ho, Shuk-Mei, van Breemen, Richard B

“…Previous studies have uncovered heightened prostatic susceptibility to hormone-induced neoplasia from early-life exposure to low-dose bisphenol A (BPA)…”
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Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants by Liu, Jialin, Banuvar, Suzanne, Viana, Marlos, Barengolts, Elena, Chen, Shao-Nong, Pauli, Guido F, van Breemen, Richard B

“…Licorice, the roots and rhizomes of L., has been used as a medicinal herb, herbal adjuvant, and flavoring agent since ancient times. Recently, licorice…”
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Does doxorubicin survive thermal ablation? Results of an ex vivo bench top study by Morrison, Joseph D, Schlager, Collin K, Lee, Amanda E, van Breemen, Richard B, Gaba, Ron C

“…We aimed to test the hypothesis that doxorubicin (DOX) survives thermal ablative heating in an ex vivo model of combined transarterial chemoembolization (TACE)…”
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