Search Results - "Breemen, Richard B."
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Affinity selection–mass spectrometry for the discovery of pharmacologically active compounds from combinatorial libraries and natural products
Published in Journal of mass spectrometry. (2021)“…Invented to address the high‐throughput screening (HTS) demands of combinatorial chemistry, affinity selection–mass spectrometry (AS‐MS) utilizes binding…”
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Antiviral activities of hemp cannabinoids
Published in Clinical science (1979) (26-04-2023)“…Hemp is an understudied source of pharmacologically active compounds and many unique plant secondary metabolites including more than 100 cannabinoids. After…”
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Affinity selection‐mass spectrometry in the discovery of anti‐SARS‐CoV‐2 compounds
Published in Mass spectrometry reviews (01-01-2024)“…Small molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2), which is the cause…”
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Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry
Published in Analytical and bioanalytical chemistry (01-12-2017)“…The metabolism of the chemoprevention agent licochalcone A, which is a chemopreventive chalcone found in abundance in the licorice species Glycyrrhiza inflata…”
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Quantitative Analysis of Phytosterols in Edible Oils Using APCI Liquid Chromatography–Tandem Mass Spectrometry
Published in Lipids (01-09-2013)“…Previous methods for the quantitative analysis of phytosterols have usually used GC–MS and require elaborate sample preparation including chemical…”
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Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry
Published in Phytochemistry reviews (01-02-2018)“…Procyanidins are polyphenols abundant in dietary fruits, vegetables, nuts, legumes, and grains with a variety of chemopreventive biological effects. Rapid…”
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Pharmacokinetics of a Single Dose of Turmeric Curcuminoids Depends on Formulation: Results of a Human Crossover Study
Published in The Journal of nutrition (01-07-2021)“…Curcuminoids from turmeric rhizome have significant health benefits but low bioavailability. To assess the pharmacokinetics of a novel natural turmeric dried…”
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Cannabinoids Block Cellular Entry of SARS-CoV‑2 and the Emerging Variants
Published in Journal of natural products (Washington, D.C.) (28-01-2022)“…As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2…”
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Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS
Published in Journal of agricultural and food chemistry (26-10-2016)“…Defined as the roots and underground stems of principally three Glycyrrhiza species, Glycyrrhiza glabra L., Glycyrrhiza uralensis Fish. ex DC., and Glycyrrhiza…”
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SPECIAL ISSUE TITLE: Special issue dedicated to Catherine Fenselau
Published in Journal of mass spectrometry. (01-02-2020)“…For five decades, Catherine Fenselau has been at the forefront of the field of biomedical mass spectrometry, which she helped shape as a scholar, educator, and…”
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Catherine Fenselau: A distinguished career dedicated to biomedical mass spectrometry
Published in Journal of mass spectrometry. (01-02-2020)Get full text
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Affinity selection–mass spectrometry for the discovery of pharmacologically active compounds from combinatorial libraries and natural products
Published in Journal of mass spectrometry. (01-05-2021)“…The Special Feature this month is jointly authored by Drs. Ruth Muchiri and Richard van Breemen, both of the Linus Pauling Institute, Oregon State University…”
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Development of Safe and Effective Botanical Dietary Supplements
Published in Journal of medicinal chemistry (12-11-2015)“…Regulated differently than drugs or foods, the market for botanical dietary supplements continues to grow worldwide. The recently implemented U.S. FDA…”
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Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
Published in Drug metabolism and disposition (01-02-2023)“…Licorice, the roots and rhizomes of L., has been used as a medicinal herb, herbal adjuvant, and flavoring agent since ancient times. Recently, licorice…”
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Role of ammonium in the ionization of phosphatidylcholines during electrospray mass spectrometry
Published in Rapid communications in mass spectrometry (15-02-2017)“…Rationale Electrospray mass spectrometry methods for the analysis of phosphatidylcholines (PCs) routinely include ammonium acetate or ammonium formate in the…”
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Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients
Published in Journal of neuroscience research (01-12-2016)“…Extracellular vesicles (EVs) are membrane nanovesicles of diverse sizes secreted by different cell types and are involved in intercellular communication. EVs…”
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Multitargeted therapy of cancer by lycopene
Published in Cancer letters (08-10-2008)“…Abstract Lycopene (ψ,ψ-carotene) is the most abundant carotenoid in tomatoes and is the red pigment of not only tomatoes but also rosehips, watermelon, papaya,…”
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Collision‐induced dissociation of phenethylamides: role of ion‐neutral complexes
Published in Rapid communications in mass spectrometry (15-09-2017)“…Rationale Phenethylamides are a large group of naturally occurring molecules found both in the plant and animal kingdoms. In addition, they are used as…”
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Ion mobility‐mass spectrometry for the separation and analysis of procyanidins
Published in Journal of mass spectrometry. (01-02-2020)“…Procyanidins are polymeric flavan‐3‐ones occurring in many plants with antioxidant and other beneficial bioactivities. They are composed of catechin and…”
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Determination of bisphenol A-glucuronide in human urine using ultrahigh-pressure liquid chromatography/tandem mass spectrometry
Published in Rapid communications in mass spectrometry (15-02-2016)“…Rationale Used widely as a plasticizer and as a monomer for plastics, bisphenol A (BPA) is under investigation as a possible endocrine disrupter. As an…”
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