Search Results - "Breeman, W A"

Gastrin-releasing peptide receptor-based targeting using bombesin analogues is superior to metabolism-based targeting using choline for in vivo imaging of human prostate cancer xenografts by Schroeder, Rogier P. J., van Weerden, W. M., Krenning, E. P., Bangma, C. H., Berndsen, S., Grievink-de Ligt, C. H., Groen, H. C., Reneman, S., de Blois, E., Breeman, W. A. P., de Jong, M.

“…Purpose Prostate cancer (PC) is a major health problem. Overexpression of the gastrin-releasing peptide receptor (GRPR) in PC, but not in the hyperplastic…”
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Radiolabelled somatostatin analogue(s) for peptide receptor scintigraphy and radionuclide therapy by Krenning, E. P., de Jong, M., Kooij, P. P. M., Breeman, W. A. P., Bakker, W. H., de Herder, W. W., van Eijck, C. H. J., Kwekkeboom, D. J., Jamar, F., Pauwels, S., Valkema, R.

“…Background: Peptide receptor scintigraphy with the radioactive somatostatin analogue, [111In-DTPA0]octreotide, is a sensitive and specific technique to show in…”
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Radiolabelled regulatory peptides for imaging and therapy by Breeman, W A P, Kwekkeboom, D J, de Blois, E, de Jong, M, Visser, T J, Krenning, E P

“…Radiolabelled peptides have shown to be an important class of radiopharmaceuticals for imaging and therapy of malignancies expressing receptors of regulatory…”
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Somatostatin receptor scintigraphy with [111In-DTPA-D-Phe1]- and [123I-Tyr3]-octreotide: the Rotterdam experience with more than 1000 patients by Krenning, E P, Kwekkeboom, D J, Bakker, W H, Breeman, W A, Kooij, P P, Oei, H Y, van Hagen, M, Postema, P T, de Jong, M, Reubi, J C

“…Various tumours, classically specified as either neuroendocrine or non-neuroendocrine, contain high numbers of somatostatin receptors, which enable in vivo…”
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Somatostatin receptor imaging, therapy and new strategies in patients with neuroendocrine tumours by Slooter, G. D., Mearadji, A., Breeman, W. A. P., Marquet, R. L., de Jong, M., Krenning, E. P., van Eijck, C. H. J.

“…Background: Somatostatin receptors have been found on a variety of neuroendocrine tumours, such as carcinoids and paragangliomas, as well as on most pancreatic…”
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Molecular imaging of reduced renal uptake of radiolabelled [DOTA0,Tyr3]octreotate by the combination of lysine and Gelofusine in rats by Rolleman, E J, Bernard, B F, Breeman, W A P, Forrer, F, de Blois, E, Hoppin, J, Gotthardt, M, Boerman, O C, Krenning, E P, de Jong, M

“…In peptide receptor radionuclide therapy (PRRT) using radiolabelled somatostatin analogues, kidney uptake of radiolabelled compound is the major dose-limiting…”
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Somatostatin receptor: scintigraphy and radionuclide therapy by Krenning, E P, Kooij, P P, Pauwels, S, Breeman, W A, Postema, P T, De Herder, W W, Valkema, R, Kwekkeboom, D J

“…Peptide receptor scintigraphy is more sensitive at the biological than anatomical level, in contrast to conventional imaging, which it complements…”
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Visualization of the thymus by substance P receptor scintigraphy in man by van Hagen, P M, Breeman, W A, Reubi, J C, Postema, P T, van den Anker-Lugtenburg, P J, Kwekkeboom, D J, Laissue, J, Waser, B, Lamberts, S W, Visser, T J, Krenning, E P

“…Substance P, an 11-amino acid neuropeptide, has an important role in modulating pain transmission through neurokinin 1 and 2 receptors. Substance P and other…”
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Receptor Scintigraphy with a Radioiodinated Somatostatin Analogue: Radiolabeling, Purification, Biologic Activity, and In Vivo Application in Animals by Bakker, Willem H, Krenning, Eric P, Breeman, Wout A, Koper, Jan W, Kooij, Peter P, Reubi, Jean-Claude, Klijn, Jan G, Visser, Theo J, Docter, Roel, Lamberts, Steven W

“…Radioiodinated Tyr-3-octreotide, a somatostatin analogue, is a useful ligand for the in vitro detection of somatostatin receptors. In this study, we have…”
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Evaluation of a radiolabelled cyclic DTPA‐RGD analogue for tumour imaging and radionuclide therapy by van Hagen, P.M., Breeman, W.A.P., Bernard, H.F., Schaar, M., Mooij, C.M., Srinivasan, A., Schmidt, M.A., Krenning, E.P., de Jong, M.

“…Tumours depend on sufficient blood supply for their growth. They are able to promote new blood vessel formation (neoangiogenesis) via angiogenic factors…”
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The role of radioactive somatostatin and its analogues in the control of tumor growth by Krenning, E P, Valkema, R, Kooij, P P, Breeman, W A, Bakker, W H, de Herder, W W, van Eijck, C H, Kwekkeboom, D J, de Jong, M, Jamar, F, Pauwels, S

“…Peptide receptor scintigraphy with the radioactive somatostatin analogue [111In-DTPA-D-Phe1]octreotide is a sensitive and specific technique to show in vivo…”
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Improving radiopeptide pharmacokinetics by adjusting experimental conditions for bombesin receptor-targeted imaging of prostate cancer by Schroeder, R P J, De Blois, E, De Ridder, C M A, Van Weerden, W M, Breeman, W A P, de Jong, M

“…Prostate cancer (PC) is a major health problem. The Gastrin-Releasing Peptide Receptor (GRPR) offers a promising target for staging and monitoring of PC since…”
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Practical aspects of peptide receptor radionuclide therapy with [177Lu][DOTA0, Tyr3]octreotate by Bakker, W H, Breeman, W A P, Kwekkeboom, D J, De Jong, L C, Krenning, E P

“…Lutetium-177 is increasingly used in patients for receptor-targeted radionuclide therapy with peptides such as [DOTA0,Tyr3]octreotate. In our therapy facility,…”
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Yttrium-90 and indium-111 labelling, receptor binding and biodistribution of [DOTA0,d-Phe1,Tyr3]octreotide, a promising somatostatin analogue for radionuclide therapy by de Jong, M, Bakker, W H, Krenning, E P, Breeman, W A, van der Pluijm, M E, Bernard, B F, Visser, T J, Jermann, E, Béhé, M, Powell, P, Mäcke, H R

“…In vitro octreotide receptor binding of [111In-DOTA0,d-Phe1, Tyr3]octreotide (111In-DOTATOC) and the in vivo metabolism of 90Y- or 111In-labelled DOTATOC were…”
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Radiotherapy with a radiolabeled somatostatin analogue, [111In-DTPA-D-Phe1]-octreotide. A case history by Krenning, E P, Kooij, P P, Bakker, W H, Breeman, W A, Postema, P T, Kwekkeboom, D J, Oei, H Y, de Jong, M, Visser, T J, Reijs, A E

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Pre‐clinical evaluation of [111In‐DTPA‐Pro1, Tyr4]bombesin, a new radioligand for bombesin‐receptor scintigraphy by Breeman, Wout A.P., De Jong, Marion, Bernard, Bert F., Kwekkeboom, Dik J., Srinivasan, Ananth, van der Pluijm, Marcel E., Hofland, Leo J., Visser, Theo J., Krenning, Eric P.

“…Bombesin (BN) is a 14‐amino‐acid neuropeptide with a high affinity for the gastrin‐releasing peptide receptor. This receptor has been found to be expressed in…”
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D-Lysine Reduction of Indium-111 Octreotide and Yttrium-90 Octreotide Renal Uptake by Bernard, Bert F, Krenning, Eric P, Breeman, Wout A.P, Rolleman, Edgar J, Bakker, Willem H, Visser, Theo J, Macke, Helmut, de Jong, Marion

“…Indium-111-DTPA-octreotide (111In-DTPAOC) is used successfully for imaging somatostatin receptor-positive lesions. A new and promising application is its use…”
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Radioiodinated somatostatin analogue RC-160: preparation, biological activity, in vivo application in rats and comparison with [123I-Tyr3]octreotide by Breeman, W A, Hofland, L J, Bakker, W H, van der Pluijm, M, van Koetsveld, P M, de Jong, M, Setyono-Han, B, Kwekkeboom, D J, Visser, T J, Lamberts, S W

“…We have evaluated the potential usefulness of the radioiodinated octapeptide RC-160, a somatostatin analogue, which might serve as a radiopharmaceutical for…”
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Pre‐clinical comparison of [DTPA0] octreotide, [DTPA0,Tyr3] octreotide and [DOTA0,Tyr3] octreotide as carriers for somatostatin receptor‐targeted scintigraphy and radionuclide therapy by De Jong, Marion, Bakker, Willem H., Breeman, Wout A. P., Bernard, Bert F., Hofland, Leo J., Visser, Theo J., Srinivasan, Ananth, Schmidt, Michelle, Béhé, Martin, Mäcke, Helmut R., Krenning, Eric P.

“…We have evaluated the potential usefulness of radiolabelled [DTPA0,Tyr3]octreotide and [DOTA0,Tyr3]octreotide as radiopharmaceuticals for somatostatin…”
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Evaluation of radiolabelled bombesin analogues for receptor‐targeted scintigraphy and radiotherapy by Breeman, Wout A.P., Hofland, Leo J., de Jong, Marion, Bernard, Bert F., Sinivasan, Ananth, Kwekkeboom, Dik J., Visser, Theo J., Krenning, Eric P.

“…The 14‐aminoacid peptide bombesin (BN) has a high affinity for the gastrin‐releasing peptide receptor which is expressed by a variety of tumours. Thus,…”
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