Search Results - "Bree, Ronan T."
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Purification of Polyhistidine-Tagged Proteins
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…His-tagging is the most widespread and versatile strategy used to purify recombinant proteins for biochemical and structural studies. Recombinant DNA methods…”
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The MRN complex: coordinating and mediating the response to broken chromosomes
Published in EMBO reports (01-09-2003)“…The MRE11–RAD50–NBS1 (MRN) protein complex has been linked to many DNA metabolic events that involve DNA double‐stranded breaks (DSBs). In vertebrate cells,…”
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Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes
Published in PLoS genetics (01-01-2009)“…Homologous recombination (HR) is initiated by DNA double-strand breaks (DSB). However, it remains unclear whether single-strand lesions also initiate HR in…”
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Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks
Published in DNA repair (10-06-2006)“…53BP1 (p53 binding protein) is a BRCT domain-containing protein that is rapidly recruited to DNA double strand breaks (DSBs). To investigate the role of 53BP1…”
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Identification of zygotic genes expressed at the midblastula transition in zebrafish
Published in Biochemical and biophysical research communications (29-06-2007)“…Early development of the embryo is directed by maternal gene products and characterised by limited zygotic gene activity, cell division synchrony and no cell…”
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Incorporating augmented reality to enrich student learning
Published in Journal of learning development in higher education (06-12-2017)“…Learning in higher education is now performed across several dimensions, for example: face-to-face in the classroom or practical sessions; engaging with…”
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The lazy teacher's handbook
Published in Journal of learning development in higher education (29-03-2015)“…Review ofThe lazy teacher's handbook: How your students learn more when you teach less, Smith J (2010),…”
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The switch from survival responses to apoptosis after chromosomal breaks
Published in DNA Repair (01-08-2004)“…Eukaryotic cells have evolved highly sophisticated cellular responses to DNA double strand breaks (DSBs) that increase the likelihood of survival. However,…”
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Book Review Journal Article -
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Comparisons between DT40 wildtype and DT40-Cre1 cells as suitable model systems for studying the DNA damage response
Published in Cell cycle (Georgetown, Tex.) (15-09-2007)Get full text
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Comparisons Between DT40 Wild Type and DT40-Cre1 Cells as Suitable Model Systems for Studying the DNA Damage Response
Published in Cell cycle (Georgetown, Tex.) (15-09-2007)“…Not yet available…”
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nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish
Published in Biochemical and biophysical research communications (05-08-2005)“…A novel, developmentally regulated gene, nanor, was identified by suppression subtractive hybridization. It is first expressed following the midblastula…”
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Cellular longevity: role of apoptosis and replicative senescence
Published in Biogerontology (Dordrecht) (01-01-2002)“…Cellular longevity refers to the lifespan of an individual cell. Normal cells have a finite lifespan and typically die by undergoing apoptosis, or enter into a…”
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Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development
Published in Biochimica et biophysica acta (07-06-2002)“…Cyclin-dependent kinase 8 (cdk8) regulates transcription by phosphorylating RNA polymerase II and TFIIH. The mechanism of zygotic transcription activation…”
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Genetic Evidence for Single-Strand Lesions Initiating Nbs1-Dependent Homologous Recombination in Diversification of Ig V in Chicken B Lymphocytes: e1000356
Published in PLoS genetics (01-01-2009)“…Homologous recombination (HR) is initiated by DNA double-strand breaks (DSB). However, it remains unclear whether single-strand lesions also initiate HR in…”
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