Search Results - "Bredow, Clara"

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity by Thery, Fabien, Martina, Lia, Asselman, Caroline, Zhang, Yifeng, Vessely, Madeleine, Repo, Heidi, Sedeyn, Koen, Moschonas, George D., Bredow, Clara, Teo, Qi Wen, Zhang, Jingshu, Leandro, Kevin, Eggermont, Denzel, De Sutter, Delphine, Boucher, Katie, Hochepied, Tino, Festjens, Nele, Callewaert, Nico, Saelens, Xavier, Dermaut, Bart, Knobeloch, Klaus-Peter, Beling, Antje, Sanyal, Sumana, Radoshevich, Lilliana, Eyckerman, Sven, Impens, Francis

“…ISG15 is an interferon-stimulated, ubiquitin-like protein that can conjugate to substrate proteins (ISGylation) to counteract microbial infection, but the…”
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VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling by Benn, Andreas, Bredow, Clara, Casanova, Isabel, Vukičević, Slobodan, Knaus, Petra

“…Several vascular disorders, such as aberrant angiogenesis, atherosclerosis and pulmonary hypertension, have been linked to dysfunctional BMP signaling…”
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The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection by Zhang, Yifeng, Thery, Fabien, Wu, Nicholas C., Luhmann, Emma K., Dussurget, Olivier, Foecke, Mariko, Bredow, Clara, Jiménez-Fernández, Daniel, Leandro, Kevin, Beling, Antje, Knobeloch, Klaus-Peter, Impens, Francis, Cossart, Pascale, Radoshevich, Lilliana

“…ISG15 is an interferon-stimulated, ubiquitin-like protein, with anti-viral and anti-bacterial activity. Here, we map the endogenous in vivo ISGylome in the…”
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Coxsackievirus B3 Exploits the Ubiquitin-Proteasome System to Facilitate Viral Replication by Voss, Martin, Braun, Vera, Bredow, Clara, Kloetzel, Peter-Michael, Beling, Antje

“…Infection by RNA viruses causes extensive cellular reorganization, including hijacking of membranes to create membranous structures termed replication…”
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ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection by Bredow, Clara, Thery, Fabien, Wirth, Eva Katrin, Ochs, Sarah, Kespohl, Meike, Kleinau, Gunnar, Kelm, Nicolas, Gimber, Niclas, Schmoranzer, Jan, Voss, Martin, Klingel, Karin, Spranger, Joachim, Renko, Kostja, Ralser, Markus, Mülleder, Michael, Heuser, Arnd, Knobeloch, Klaus-Peter, Scheerer, Patrick, Kirwan, Jennifer, Brüning, Ulrike, Berndt, Nikolaus, Impens, Francis, Beling, Antje

“…Virus infection triggers inflammation and, may impose nutrient shortage to the heart. Supported by type I interferon (IFN) signalling, cardiomyocytes…”
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TF-FVIIa PAR2-β-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice by Kespohl, Meike, Goetzke, Carl Christoph, Althof, Nadine, Bredow, Clara, Kelm, Nicolas, Pinkert, Sandra, Bukur, Thomas, Bukur, Valesca, Grunz, Kristin, Kaur, Dilraj, Heuser, Arnd, Mülleder, Michael, Sauter, Martina, Klingel, Karin, Weiler, Hartmut, Berndt, Nikolaus, Gaida, Matthias M., Ruf, Wolfram, Beling, Antje

“…BACKGROUND: Accumulating evidence implicates the activation of G-protein–coupled PARs (protease-activated receptors) by coagulation proteases in the regulation…”
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A cytosolic disulfide bridge‐supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A by Voss, Martin, Kleinau, Gunnar, Gimber, Niclas, Janek, Katharina, Bredow, Clara, Thery, Fabien, Impens, Francis, Schmoranzer, Jan, Scheerer, Patrick, Kloetzel, Peter‐Michael, Beling, Antje

“…RNA viruses in the Picornaviridae family express a large 250 kDa viral polyprotein that is processed by virus‐encoded proteinases into mature functional…”
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Abstract 12674: LDL Transcytosis by SR-BI Requires Signaling That is Distinct From Reverse Cholesterol Transport by Sugiyama, Michael, Neculai, Dante, Zyla, Roman, Bredow, Clara, Nyegaard, Steffen, Lee, Warren L

“…IntroductionHow LDL crosses an intact endothelial layer to initiate atherosclerosis is poorly understood, although it is postulated to involve LDL…”
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TF-FVIIa PAR2-β-Arrestin in Mouse Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection by Kespohl, Meike, Goetzke, Carl Christoph, Althof, Nadine, Bredow, Clara, Kelm, Nicolas, Pinkert, Sandra, Bukur, Thomas, Bukur, Valesca, Grunz, Kristin, Kaur, Dilraj, Heuser, Arnd, Mülleder, Michael, Sauter, Martina, Klingel, Karin, Weiler, Hartmut, Berndt, Nikolaus, Gaida, Matthias M, Ruf, Wolfram, Beling, Antje

“…Accumulating evidence implicates the activation of G-protein-coupled PARs (protease-activated receptors) by coagulation proteases in the regulation of innate…”
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Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming by Kespohl, Meike, Bredow, Clara, Klingel, Karin, Voß, Martin, Paeschke, Anna, Zickler, Martin, Poller, Wolfgang, Kaya, Ziya, Eckstein, Johannes, Fechner, Henry, Spranger, Joachim, Fähling, Michael, Wirth, Eva Katrin, Radoshevich, Lilliana, Thery, Fabien, Impens, Francis, Berndt, Nikolaus, Knobeloch, Klaus-Peter, Beling, Antje

“…Protein modification with ISG15 (ISGylation) represents a major type I IFN-induced antimicrobial system. Common mechanisms of action and species-specific…”
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