Search Results - "Brech, A."

Glomerular Collagen V Codeposition and Hepatic Perisinusoidal Collagen III Accumulation in Canine Collagen Type III Glomerulopathy by Rørtveit, R., Reiten, M. R., Lingaas, F., Sveri, S. B., Brech, A., Espenes, A., Jansen, J. H.

“…Collagen type III glomerulopathy, also known as collagenofibrotic glomerulopathy, is a rare renal disease of unknown pathogenesis. The disease occurs in humans…”
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338: Smad ubiquitination regulatory factor 2 (Smurf2) regulates the gap junction protein connexin43 during mitosis by Fykerud, T.A, Koirala, S.D, Totland, M.Z, Knudsen, L.M, Yohannes, Z, Omori, Y, Brech, A, Leithe, E

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Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver by Løvdal, T, Andersen, E, Brech, A, Berg, T

“…Soluble circulating immunoglobulin G immune complexes are mainly eliminated by the liver, predominantly by uptake in the Kupffer cells, but also the liver…”
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Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells by Kjeken, R, Mousavi, S A, Brech, A, Griffiths, G, Berg, T

“…Liver endothelial cells (LECs) play an important homoeostatic role by removing potentially harmful macromolecules from blood. The extremely efficient…”
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540 Post-translational mechanisms involved in downregulation of the gap junction protein Connexin43 in colorectal cancer by Leithe, E, Sirnes, S, Bruun, J, Kjenseth, A, Lind, G.E, Kolberg, M, Stenmark, H, Brech, A, Lothe, R.A, Rivedal, E

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death by Bjørkøy, Geir, Lamark, Trond, Brech, Andreas, Outzen, Heidi, Perander, Maria, Øvervatn, Aud, Stenmark, Harald, Johansen, Terje

“…Autophagic degradation of ubiquitinated protein aggregates is important for cell survival, but it is not known how the autophagic machinery recognizes such…”
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The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk by Clement, Dennis, Szabo, Edina K, Krokeide, Silje Zandstra, Wiiger, Merete Thune, Vincenti, Marianna, Palacios, Daniel, Chang, Young-Tae, Grimm, Christian, Patel, Sandip, Stenmark, Harald, Brech, Andreas, Majhi, Rakesh Kumar, Malmberg, Karl-Johan

“…Cytotoxic lymphocytes eliminate cancer cells through the release of lytic granules, a specialized form of secretory lysosomes. This compartment is part of the…”
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Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity by Husebye, Harald, Halaas, Øyvind, Stenmark, Harald, Tunheim, Gro, Sandanger, Øystein, Bogen, Bjarne, Brech, Andreas, Latz, Eicke, Espevik, Terje

“…Immune responses are initiated when molecules of microbial origin are sensed by the Toll‐like receptors (TLRs). We now report the identification of essential…”
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Modulation of lytic molecules restrain serial killing in γδ T lymphocytes by Sandoz, Patrick A., Kuhnigk, Kyra, Szabo, Edina K., Thunberg, Sarah, Erikson, Elina, Sandström, Niklas, Verron, Quentin, Brech, Andreas, Watzl, Carsten, Wagner, Arnika K., Alici, Evren, Malmberg, Karl-Johan, Uhlin, Michael, Önfelt, Björn

“…γδ T cells play a pivotal role in protection against various types of infections and tumours, from early childhood on and throughout life. They consist of…”
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ESCRTs and Fab1 Regulate Distinct Steps of Autophagy by Rusten, Tor Erik, Vaccari, Thomas, Lindmo, Karine, Rodahl, Lina M.W., Nezis, Ioannis P., Sem-Jacobsen, Catherine, Wendler, Franz, Vincent, Jean-Paul, Brech, Andreas, Bilder, David, Stenmark, Harald

“…Eukaryotes use autophagy to turn over organelles, protein aggregates, and cytoplasmic constituents. The impairment of autophagy causes developmental defects,…”
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Hrs Regulates Multivesicular Body Formation via ESCRT Recruitment to Endosomes by Bache, Kristi G., Brech, Andreas, Mehlum, Anja, Stenmark, Harald

“…Hrs and the endosomal sorting complexes required for transport, ESCRT-I, -II, and -III, are involved in the endosomal sorting of membrane proteins into…”
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Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway by Rusten, Tor Erik, Lindmo, Karine, Juhász, Gábor, Sass, Miklós, Seglen, Per O., Brech, Andreas, Stenmark, Harald

“…Eukaryotic cells catabolize their own cytoplasm by autophagy in response to amino acid starvation and inductive signals during programmed tissue remodeling and…”
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Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes by Simonsen, Anne, Birkeland, Hanne C G, Gillooly, David J, Mizushima, Noboru, Kuma, Akiko, Yoshimori, Tamotsu, Slagsvold, Thomas, Brech, Andreas, Stenmark, Harald

“…Phosphatidylinositol-3-phosphate [PtdIns(3)P] regulates endocytic and autophagic membrane traffic. In order to understand the downstream effects of PtdIns(3)P…”
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Involvement of Early and Late Lysosomes in the Degradation of Mannosylated Ligands by Rat Liver Endothelial Cells by Kjeken, R., Brech, A., Løvdal, T., Roos, N., Berg, T.

“…The intracellular transport and degradation of endocytosed mannosylated albumin (Man-BSA) was studied in cell cultures of rat liver endothelial cells by…”
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The tankyrase inhibitor G007-LK inhibits small intestine LGR5 + stem cell proliferation without altering tissue morphology by Norum, Jens Henrik, Skarpen, Ellen, Brech, Andreas, Kuiper, Raoul, Waaler, Jo, Krauss, Stefan, Sørlie, Therese

“…The WNT pathway regulates intestinal stem cells and is frequently disrupted in intestinal adenomas. The pathway contains several potential biotargets for…”
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Endocytic processing of connexin43 gap junctions: a morphological study by Leithe, Edward, Brech, Andreas, Rivedal, Edgar

“…Gap junctions are plasma membrane areas enriched in channels that provide direct intercellular communication. Gap junctions have a high turnover rate; however,…”
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Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors by Haugsten, Ellen Margrethe, Sørensen, Vigdis, Brech, Andreas, Olsnes, Sjur, Wesche, Jørgen

“…Many growth factors and cytokines bind to more than one receptor, but in many cases the different roles of the separate receptors in signal transduction are…”
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Nathaniel and Edward Pigott, itinerant astronomers by McConnell, A., Brech, A.

“…Dictionary of national biography…”
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Alix regulates cortical actin and the spatial distribution of endosomes by Cabezas, Alicia, Bache, Kristi G, Brech, Andreas, Stenmark, Harald

“…Alix/AIP1 is a proline-rich protein that has been implicated in apoptosis, endocytic membrane trafficking and viral budding. To further elucidate the functions…”
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EEA1 links PI(3)K function to Rab5 regulation of endosome fusion by Stenmark, Harald, Simonsen, Anne, Lippe, Roger, Christoforidis, Savvas, Gaullier, Jean-Michel, Brech, Andreas, Callaghan, Judy, Toh, Ban-Hock, Murphy, Carol, Zerial, Marino

“…GTPases and lipid kinases regulate membrane traffic along the endocytic pathway by mechanisms that are not completely understood. Fusion between early…”
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