Search Results - "Breccia, Javier"
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Peculiarities and systematics of microbial diglycosidases, and their applications in food technology
Published in Applied microbiology and biotechnology (01-04-2021)“…Diglycosidases are endo-β-glucosidases that hydrolyze the heterosidic linkage of diglycoconjugates, thereby releasing in a single reaction the disaccharide and…”
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Screening and quantification of the enzymatic deglycosylation of the plant flavonoid rutin by UV–visible spectrometry
Published in Food chemistry (15-08-2017)“…•Quantification of rutin-hydrolyzing enzymes using the natural substrate.•Determination of rutin-deglycosylation activity in buckwheat flours and…”
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Acremonium sp. diglycosidase-aid chemical diversification: valorization of industry by-products
Published in Applied microbiology and biotechnology (01-12-2024)“…The fungal diglycosidase α-rhamnosyl-β-glucosidase I (αRβG I) from Acremonium sp. DSM 24697 catalyzes the glycosylation of various OH-acceptors using the…”
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Rutinosides-derived from Sarocladium strictum 6-O-α-rhamnosyl-β-glucosidase show enhanced anti-tumoral activity in pancreatic cancer cells
Published in Microbial cell factories (08-05-2024)“…Low targeting efficacy and high toxicity continue to be challenges in Oncology. A promising strategy is the glycosylation of chemotherapeutic agents to improve…”
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Glycoconjugation: An approach to cancer therapeutics
Published in World journal of clinical oncology (24-03-2020)“…Cancer constitutes the second leading cause of death globally and is considered to have been responsible for an estimated 9.6 million fatalities in 2018…”
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Glycosylated 4‐methylumbelliferone as a targeted therapy for hepatocellular carcinoma
Published in Liver international (01-02-2022)“…Background & Aims Reaching efficacious drug delivery to target cells/tissues represents a major obstacle in the current treatment of solid malignancies…”
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The flavonoid degrading fungus Acremonium sp. DSM 24697 produces two diglycosidases with different specificities
Published in Applied microbiology and biotechnology (01-12-2019)“…Diglycosidases hydrolyze the heterosidic linkage of diglycoconjugates, releasing the disaccharide and the aglycone. Usually, these enzymes do not hydrolyze or…”
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Fish waste silage, a green process for low feedstock availability. A Review
Published in Agronomía mesoamericana (01-08-2023)“…Introduction. Different fishing activities generate a waste volume related to the processing species (viscera, heads and bones), the discards of the companion…”
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Enzymatic deglycosylation of flavonoids in deep eutectic solvents-aqueous mixtures: paving the way for sustainable flavonoid chemistry
Published in Journal of molecular catalysis. B, Enzymatic (01-08-2016)“…[Display omitted] •Enzymatic flavonoid deglycosylation in DES and DES-components.•Single reaction using a diglycosidase from Acremonium sp. DSM24697.•A system…”
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Evidence for repeated gene duplications in Tritrichomonas foetus supported by EST analysis and comparison with the Trichomonas vaginalis genome
Published in Veterinary parasitology (15-12-2014)“…•Repeatedly duplicated genes would be common in the T. foetus genome.•Genes involved in the energetic metabolism and in cell structure show distinct expression…”
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Enzyme‐mediated transglycosylation of rutinose (6‐O‐α‐l‐rhamnosyl‐d‐glucose) to phenolic compounds by a diglycosidase from Acremonium sp. DSM 24697
Published in Biotechnology and applied biochemistry (01-01-2019)“…The structure of the carbohydrate moiety of a natural phenolic glycoside can have a significant effect on the molecular interactions and physicochemical and…”
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Quantification of hesperidin in citrus-based foods using a fungal diglycosidase
Published in Food chemistry (15-10-2012)“…► A spectrophotometric method was developed to quantify hesperidin of citrus-based foods. ► It uses a fungal diglycosidase to quantitatively hydrolyse…”
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Polyvinyl Alcohol–Pectin Cryogel Films for Controlled Release of Enrofloxacin
Published in Applied biochemistry and biotechnology (01-07-2012)“…The release of enrofloxacin entrapped in polyvinyl alcohol (PVA) cryogel at pH 5.5 showed a first-order kinetic, releasing 69.7% of the antibiotic after 4.5 h…”
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Bacteria as source of diglycosidase activity: Actinoplanes missouriensis produces 6-O-α-L-rhamnosyl-β-D-glucosidase active on flavonoids
Published in Applied microbiology and biotechnology (01-04-2016)“…Bacteria represent an underexplored source of diglycosidases. Twenty-five bacterial strains from the genera Actinoplanes, Bacillus, Corynebacterium,…”
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Loop mediated isothermal amplification of 5.8S rDNA for specific detection of Tritrichomonas foetus
Published in Veterinary parasitology (31-03-2013)“…Tritrichomonas foetus is the causative agent of bovine trichomonosis, a sexually transmitted disease leading to infertility and abortion. A test based on loop…”
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Extracellular monoenzyme deglycosylation system of 7-O-linked flavonoid β-rutinosides and its disaccharide transglycosylation activity from Stilbella fimetaria
Published in Archives of microbiology (01-05-2010)“…We screened for microorganisms able to use flavonoids as a carbon source; and one isolate, nominated Stilbella fimetaria SES201, was found to possess a…”
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Operational stabilization of fungal α-rhamnosyl-β-glucosidase by immobilization on chitosan composites
Published in Process biochemistry (1991) (01-12-2011)“…► The enzyme α-rhamnosyl-β-glucosidase was immobilized onto chitosan–silica gel beads coated with polyethyleneimine. ► The immobilized enzyme was stable in…”
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α-Rhamnosyl-β-glucosidase-Catalyzed Reactions for Analysis and Biotransformations of Plant-Based Foods
Published in Journal of agricultural and food chemistry (26-10-2011)“…Most aroma compounds exist in vegetal tissues as disaccharide conjugates, rutinose being an abundant sugar moiety in grapes. The availability of aroma…”
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Polyethyleneimine coating of magnetic particles increased the stability of an immobilized diglycosidase
Published in Biotechnology and applied biochemistry (01-01-2015)“…The diglycosidase, α‐rhamnosyl‐β‐glucosidase, from Acremonium sp. DSM24697 was immobilized by adsorption and cross‐linking onto polyaniline–iron (PI)…”
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Polyethyleneimine–protein interactions and implications on protein stability
Published in International journal of biological macromolecules (01-07-2010)“…Protein stability assessment of seven model proteins in the presence of low molecular weight polyethyleneimine (PEI, MW 2000 Da) was performed. Thermodynamic…”
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