Search Results - "Brégeon, D"

Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models by Lhospice, F, Brégeon, D, Belmant, C, Dennler, P, Chiotellis, A, Fischer, E, Gauthier, L, Boëdec, A, Rispaud, H, Savard-Chambard, S, Represa, A, Schneider, N, Paturel, C, Sapet, M, Delcambre, C, Ingoure, S, Viaud, N, Bonnafous, C, Schibli, R, Romagné, F

“…Antibody–drug conjugates (ADCs) have demonstrated clinical benefits that have led to the recent FDA approval of KADCYLA and ADCETRIS. Most ADCs that are…”
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Thiazolinium and imidazolium chiral ionic liquids derived from natural amino acid derivatives by Brégeon, D., Levillain, J., Guillen, F., Plaquevent, J.-C., Gaumont, A.-C.

“…Starting from commercially available amino acid derivatives, two novel families of chiral ionic liquids having either a thiazolinium or an imidazolium cation…”
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Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift by Brégeon, D, Colot, V, Radman, M, Taddei, F

“…Errors during gene expression from DNA to proteins via transcription and translation may be deleterious for the functional maintenance of cells. In this paper,…”
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Chiral ionic liquids, a renewal for the chemistry of chiral solvents? Design, synthesis and applications for chiral recognition and asymmetric synthesis by Baudequin, Christine, Brégeon, Delphine, Levillain, Jocelyne, Guillen, Frédéric, Plaquevent, Jean-Christophe, Gaumont, Annie-Claude

“…Chiral ionic solvents were almost unexplored before the last five years. This field which is of increasing importance could constitute a renewal for the…”
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Transcriptional Mutagenesis Induced by Uracil and 8-Oxoguanine in Escherichia coli by Brégeon, Damien, Doddridge, Zara A, You, Ho Jin, Weiss, Bernard, Doetsch, Paul W

“…Cells exposed to DNA damaging agents in their natural environment do not undergo continuous cycles of replication but are more frequently engaged in gene…”
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( S)-Histidine: the ideal precursor for a novel family of chiral aminoacid and peptidic ionic liquids by Guillen, Frédéric, Brégeon, Delphine, Plaquevent, Jean-Christophe

“…( S)-Histidine is shown to be a powerful chiral precursor for the construction of a new series of imidazolium-containing chiral ionic liquids, in which the…”
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Reliable method for generating double-stranded DNA vectors containing site-specific base modifications by Brégeon, Damien, Doetsch, Paul W

“…Cells of all living organisms are continuously exposed to physical and chemical agents that damage DNA and alter the integrity of their genomes. Despite the…”
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Inefficient mismatch repair: genetic defects and down regulation by Brégeon, Damien, Matic, Ivan, Radman, Miroslav, Taddei, François

“…The mismatch repair system is involved in the maintenance of genomic integrity by editing DNA replication and recombination. However, although most mutations…”
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Hypothetical role of RNA damage avoidance in preventing human disease by Brégeon, Damien, Sarasin, Alain

“…Most of nucleic acids damaging agents are not only restricted to DNA but equally affect DNA and RNA molecules. Considering that RNA damage could be very toxic…”
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Persistance d'importantes variations du BASDAI et du BASFI après trois cures d'infliximab : difficultés à définir un échappement dans les spondylarthropathies (SpA) by Tortellijer, L., Chevalet-Muller, F., Lavy-Bregeon, D., Maugars, Y., Berthelot, J.-M.

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