Search Results - "Brazil, Bill T"

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    The Binding of Bis-ANS to the Isolated GroEL Apical Domain Fragment Induces the Formation of a Folding Intermediate with Increased Hydrophobic Surface Not Observed in Tetradecameric GroEL by Smoot, Alison L, Panda, Markandeswar, Brazil, Bill T, Buckle, Ashley M, Fersht, Alan R, Horowitz, Paul M

    Published in Biochemistry (Easton) (10-04-2001)
    “…The extent of hydrophobic exposure upon bis-ANS binding to the functional apical domain fragment of GroEL, or minichaperone (residues 191−345), was…”
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    Divalent Cations Can Induce the Exposure of GroEL Hydrophobic Surfaces and Strengthen GroEL Hydrophobic Binding Interactions by Brazil, Bill T., Ybarra, Jesse, Horowitz, Paul M.

    Published in The Journal of biological chemistry (01-02-1998)
    “…Fluorescent and non-fluorescent probes have been used to show that divalent cations (Ca 2+ , Mg 2+ , Mn 2+ , and Zn 2+ ) significantly increase hydrophobic…”
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    Model Peptide Studies Demonstrate That Amphipathic Secondary Structures Can Be Recognized by the Chaperonin GroEL (cpn60) by Brazil, B T, Cleland, J L, McDowell, R S, Skelton, N J, Paris, K, Horowitz, P M

    Published in The Journal of biological chemistry (21-02-1997)
    “…The molecular chaperone cpn60 binds many unfolded proteins and facilitates their proper folding. Synthetic peptides have been used to probe the question of how…”
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    Photoincorporation of fluorescent probe into GroEL: defining site of interaction by Seale, J W, Brazil, B T, Horowitz, P M

    Published in Methods in enzymology (1998)
    “…We have elucidated conditions for the covalent incorporation of a nonspecific hydrophobic probe, bisANS, into various proteins. Using this method, we are able…”
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