Search Results - "Bray, James E."

Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications by Jolley, Keith A, Bray, James E, Maiden, Martin C J

“…The PubMLST.org website hosts a collection of open-access, curated databases that integrate population sequence data with provenance and phenotype information…”
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Disease-associated genotypes of the commensal skin bacterium Staphylococcus epidermidis by Méric, Guillaume, Mageiros, Leonardos, Pensar, Johan, Laabei, Maisem, Yahara, Koji, Pascoe, Ben, Kittiwan, Nattinee, Tadee, Phacharaporn, Post, Virginia, Lamble, Sarah, Bowden, Rory, Bray, James E., Morgenstern, Mario, Jolley, Keith A., Maiden, Martin C. J., Feil, Edward J., Didelot, Xavier, Miragaia, Maria, de Lencastre, Herminia, Moriarty, T. Fintan, Rohde, Holger, Massey, Ruth, Mack, Dietrich, Corander, Jukka, Sheppard, Samuel K.

“…Some of the most common infectious diseases are caused by bacteria that naturally colonise humans asymptomatically. Combating these opportunistic pathogens…”
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A Point Prevalence Survey of Antibiotic Resistance in the Irish Environment, 2018–2019 by Hooban, Brigid, Fitzhenry, Kelly, Cahill, Niamh, Joyce, Aoife, O' Connor, Louise, Bray, James E., Brisse, Sylvain, Passet, Virginie, Abbas Syed, Raza, Cormican, Martin, Morris, Dearbháile

“…•National evaluation of antibiotic resistance in sewage sources and water bodies.•Detection of carbapenemase producers in waters designated of good/excellent…”
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Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family by Hillringhaus, Lars, Yue, Wyatt W., Rose, Nathan R., Ng, Stanley S., Gileadi, Carina, Loenarz, Christoph, Bello, Simon H., Bray, James E., Schofield, Christopher J., Oppermann, Udo

“…Nϵ-Methylations of histone lysine residues play critical roles in cell biology by “marking” chromatin for transcriptional activation or repression. Lysine…”
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Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus by Lin, Gu-Lung, Drysdale, Simon B., Snape, Matthew D., O’Connor, Daniel, Brown, Anthony, MacIntyre-Cockett, George, Mellado-Gomez, Esther, de Cesare, Mariateresa, Ansari, M. Azim, Bonsall, David, Bray, James E., Jolley, Keith A., Bowden, Rory, Aerssens, Jeroen, Bont, Louis, Openshaw, Peter J. M., Martinon-Torres, Federico, Nair, Harish, Golubchik, Tanya, Pollard, Andrew J.

“…Respiratory syncytial virus (RSV) is the leading cause of hospitalisation for respiratory infection in young children. RSV disease severity is known to be…”
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Distribution of class 1 integrons in historic and contemporary collections of human pathogenic Escherichia coli by Sütterlin, Susanne, Bray, James E, Maiden, Martin C. J, Tano, Eva

“…Integrons play a major role in the evolution and spread of antimicrobial resistance in human pathogens, including Escherichia coli. This study describes the…”
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Evolution of Sequence Type 4821 Clonal Complex Hyperinvasive and Quinolone-Resistant Meningococci by Chen, Mingliang, Harrison, Odile B, Bratcher, Holly B, Bo, Zhiyan, Jolley, Keith A, Rodrigues, Charlene M C, Bray, James E, Guo, Qinglan, Zhang, Xi, Chen, Min, Maiden, Martin C J

“…Expansion of quinolone-resistant Neisseria meningitidis clone China from sequence type (ST) 4821 clonal complex (CC4821) caused a serogroup shift from…”
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Genomic epidemiology of age-associated meningococcal lineages in national surveillance: an observational cohort study by Hill, Dorothea M C, BA, Lucidarme, Jay, PhD, Gray, Stephen J, PhD, Newbold, Lynne S, PhD, Ure, Roisin, MSc, Brehony, Carina, DPhil, Harrison, Odile B, PhD, Bray, James E, PhD, Jolley, Keith A, PhD, Bratcher, Holly B, MSc, Parkhill, Julian, Prof, Tang, Christoph M, Prof, Borrow, Ray, Prof, Maiden, Martin C J, Prof

“…Summary Background Invasive meningococcal disease (IMD) is a worldwide health issue that is potentially preventable with vaccination. In view of its sporadic…”
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Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia by Mowlaboccus, Shakeel, Jolley, Keith A, Bray, James E, Pang, Stanley, Lee, Yung Thin, Bew, Jane D, Speers, David J, Keil, Anthony D, Coombs, Geoffrey W, Kahler, Charlene M

“…In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used…”
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Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity by NG, Stanley S, KAVANAGH, Kathryn L, ROSE, Nathan R, OFFER, John, SCHEINOST, Johanna C, BOROWSKI, Tomasz, SUNDSTROM, Michael, SCHOFIELD, Christopher J, OPPERMANN, Udo, MCDONOUGH, Michael A, BUTLER, Danica, PILKA, Ewa S, LIENARD, Benoit M. R, BRAY, James E, SAVITSKY, Pavel, GILEADI, Opher, VON DELFT, Frank

“…Post-translational histone modification has a fundamental role in chromatin biology and is proposed to constitute a 'histone code' in epigenetic regulation…”
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The human short-chain dehydrogenase/reductase (SDR) superfamily: A bioinformatics summary by Bray, James E., Marsden, Brian D., Oppermann, Udo

“…The short-chain dehydrogenase/reductase (SDR) superfamily represents one of the largest protein superfamilies known to date. Enzymes of this family usually…”
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cgMLST characterisation of invasive Neisseria meningitidis serogroup C and W strains associated with increasing disease incidence in the Republic of Ireland by Mulhall, Robert M, Bennett, Desiree E, Bratcher, Holly B, Jolley, Keith A, Bray, James E, O'Lorcain, Piaras P, Cotter, Suzanne M, Maiden, Martin C J, Cunney, Robert J

“…Since 2013 MenC and MenW disease incidence and associated mortality rates have increased in the Republic of Ireland. From 2002/2003 to 2012/2013, the average…”
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Defining the estimated core genome of bacterial populations using a Bayesian decision model by van Tonder, Andries J, Mistry, Shilan, Bray, James E, Hill, Dorothea M C, Cody, Alison J, Farmer, Chris L, Klugman, Keith P, von Gottberg, Anne, Bentley, Stephen D, Parkhill, Julian, Jolley, Keith A, Maiden, Martin C J, Brueggemann, Angela B

“…The bacterial core genome is of intense interest and the volume of whole genome sequence data in the public domain available to investigate it has increased…”
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The domestication of the probiotic bacterium Lactobacillus acidophilus by Bull, Matthew J., Jolley, Keith A., Bray, James E., Aerts, Maarten, Vandamme, Peter, Maiden, Martin C. J., Marchesi, Julian R., Mahenthiralingam, Eshwar

“…Lactobacillus acidophilus is a Gram-positive lactic acid bacterium that has had widespread historical use in the dairy industry and more recently as a…”
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Hierarchical genomic analysis of carried and invasive serogroup A Neisseria meningitidis during the 2011 epidemic in Chad by Diallo, Kanny, Gamougam, Kadija, Daugla, Doumagoum M, Harrison, Odile B, Bray, James E, Caugant, Dominique A, Lucidarme, Jay, Trotter, Caroline L, Hassan-King, Musa, Stuart, James M, Manigart, Olivier, Greenwood, Brian M, Maiden, Martin C J

“…Serogroup A Neisseria meningitidis (NmA) was the cause of the 2011 meningitis epidemics in Chad. This bacterium, often carried asymptomatically, is considered…”
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Genomics Reveals the Worldwide Distribution of Multidrug-Resistant Serotype 6E Pneumococci by van Tonder, Andries J, Bray, James E, Roalfe, Lucy, White, Rebecca, Zancolli, Marta, Quirk, Sigríður J, Haraldsson, Gunnsteinn, Jolley, Keith A, Maiden, Martin C J, Bentley, Stephen D, Haraldsson, Ásgeir, Erlendsdóttir, Helga, Kristinsson, Karl G, Goldblatt, David, Brueggemann, Angela B

“…The pneumococcus is a leading pathogen infecting children and adults. Safe, effective vaccines exist, and they work by inducing antibodies to the…”
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Wild bird‐associated Campylobacter jejuni isolates are a consistent source of human disease, in Oxfordshire, United Kingdom by Cody, Alison J, McCarthy, Noel D, Bray, James E, Wimalarathna, Helen M. L, Colles, Frances M, Jansen van Rensburg, Melissa J, Dingle, Kate E, Waldenström, Jonas, Maiden, Martin C. J

“…The contribution of wild birds as a source of human campylobacteriosis was investigated in Oxfordshire, United Kingdom (UK) over a 10 year period. The probable…”
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High-Definition Macromolecular Composition of Yeast RNA-Processing Complexes by Krogan, Nevan J., Peng, Wen-Tao, Cagney, Gerard, Robinson, Mark D., Haw, Robin, Zhong, Gouqing, Guo, Xinghua, Zhang, Xin, Canadien, Veronica, Richards, Dawn P., Beattie, Bryan K., Lalev, Atanas, Zhang, Wen, Davierwala, Armaity P., Mnaimneh, Sanie, Starostine, Andrei, Tikuisis, Aaron P., Grigull, Jorg, Datta, Nira, Bray, James E., Hughes, Timothy R., Emili, Andrew, Greenblatt, Jack F.

“…A remarkably large collection of evolutionarily conserved proteins has been implicated in processing of noncoding RNAs and biogenesis of ribonucleoproteins. To…”
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Genomic Analyses of >3,100 Nasopharyngeal Pneumococci Revealed Significant Differences Between Pneumococci Recovered in Four Different Geographical Regions by van Tonder, Andries J, Bray, James E, Jolley, Keith A, Jansen van Rensburg, Melissa, Quirk, Sigríður J, Haraldsson, Gunnsteinn, Maiden, Martin C J, Bentley, Stephen D, Haraldsson, Ásgeir, Erlendsdóttir, Helga, Kristinsson, Karl G, Brueggemann, Angela B

“…Understanding the structure of a bacterial population is essential in order to understand bacterial evolution. Estimating the core genome (those genes common…”
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Genomic Analysis of the Evolution and Global Spread of Hyper-invasive Meningococcal Lineage 5 by Harrison, Odile B., Bray, James E., Maiden, Martin C.J., Caugant, Dominique A.

“…The predominant model for bacterial pandemics is the emergence of a virulent variant that diversifies as it spreads in human populations. We investigated a…”
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