Search Results - "Bravo Nuevo, Arturo"
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Preclinical study of the long‐range safety and anti‐inflammatory effects of high‐dose oral meglumine
Published in Journal of cellular biochemistry (01-07-2019)“…Meglumine is a methylamino derivative of sorbitol that is an approved drug excipient. Recent preclinical studies suggest that administration of high‐dose oral…”
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2
Acquired Resilience: An Evolved System of Tissue Protection in Mammals
Published in Dose-Response (01-10-2018)“…This review brings together observations on the stress-induced regulation of resilience mechanisms in body tissues. It is argued that the stresses that induce…”
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Book Review Journal Article -
3
RhoB antibody alters retinal vascularization in models of murine retinopathy
Published in Journal of cellular biochemistry (01-06-2019)“…Neovascularization in cancer or retinopathy is driven by pathological changes that foster abnormal sprouting of endothelial cells. Mouse genetic studies…”
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Hyperoxia‐Induced Preretinal Membrane Formation and Retinal Detachment in the Mouse
Published in The FASEB journal (01-05-2022)“…Background Retinal detachment (RD) is a vision‐threatening consequence of several conditions including retinopathy of prematurity (ROP). Numerous studies have…”
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Intravitreal injection of Noggin ameliorates retinal degeneration in a mouse model of retinitis pigmentosa
Published in Acta ophthalmologica (Oxford, England) (01-01-2024)“…Purpose: To determine the therapeutic efficacy of intravitreal injections of Noggin in a rodent model of retinitis pigmentosa (RP). Noggin is expressed by…”
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Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway
Published in International journal of molecular sciences (20-01-2023)“…Cholesterol accumulation in macrophages leads to the formation of foam cells and increases the risk of developing atherosclerosis. We have verified whether…”
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Normalization of Oxygen‐Induced Retinopathy in the Mouse Supplementation with Myo/Nog Cells
Published in The FASEB journal (01-05-2022)“…Introduction Retinopathy of Prematurity (ROP) is the leading cause of blindness in children, affecting 50% of infants born prior to gestational week 32. ROP is…”
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Brain-specific angiogenesis inhibitor 1 is expressed in the Myo/Nog cell lineage
Published in PloS one (02-07-2020)“…The Myo/Nog cell lineage was discovered in the chick embryo and is also present in adult mammalian tissues. The cells are named for their expression of mRNA…”
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Myo/Nog cells are nonprofessional phagocytes
Published in PloS one (24-08-2020)“…Myo/Nog cells were discovered in the chick embryo epiblast. Their expression of MyoD reflects a commitment to the skeletal muscle lineage and capacity to…”
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10
Role of Myo/Nog Cells in Neuroprotection: Evidence from the Light Damaged Retina
Published in PloS one (18-01-2017)“…To identify Myo/Nog cells in the adult retina and test their role in protecting retinal photoreceptors from light damage. Light damage was induced by exposing…”
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11
Myo/Nog cells: targets for preventing the accumulation of skeletal muscle-like cells in the human lens
Published in PloS one (01-04-2014)“…Posterior capsule opacification (PCO) is a vision impairing condition that arises in some patients following cataract surgery. The fibrotic form of PCO is…”
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12
Biological Response of Treatment with Saffron Petal Extract on Cytokine-Induced Oxidative Stress and Inflammation in the Caco-2/Human Leukemia Monocytic Co-Culture Model
Published in Antioxidants (17-10-2024)“…The pathogenesis of Inflammatory Bowel Disease (IBD) involves complex mechanisms, including immune dysregulation, gut microbiota imbalances, oxidative stress,…”
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13
Acute Response and Neuroprotective Role of Myo/Nog Cells Assessed in a Rat Model of Focal Brain Injury
Published in Frontiers in neuroscience (07-12-2021)“…Focal brain injury in the form of a needlestick (NS) results in cell death and induces a self-protective response flanking the lesion. Myo/Nog cells are…”
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Myo/Nog Cells Increase in Response to Elevated Intraocular Pressure and Mitigate Ganglion Cell Death in a Mouse Model of Glaucoma
Published in Applied sciences (01-11-2023)“…Glaucoma is one of the leading causes of blindness worldwide. Decreased aqueous humor drainage causes an increase in intraocular pressure (IOP), which in turn…”
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Meglumine exerts protective effects against features of metabolic syndrome and type II diabetes
Published in PloS one (27-02-2014)“…Metabolic syndrome, diabetes and diabetes complications pose a growing medical challenge worldwide, accentuating the need of safe and effective strategies for…”
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RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy
Published in International immunology (01-10-2011)“…RhoB, a member of the Rho subfamily of small GTPases, mediates diverse cellular functions, including cytoskeletal organization, cell transformation and vesicle…”
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Myo/Nog Cells Give Rise to Myofibroblasts During Epiretinal Membrane Formation in a Mouse Model of Proliferative Vitreoretinopathy
Published in Investigative ophthalmology & visual science (01-02-2023)“…Myo/Nog cells are the source of myofibroblasts in the lens and synthesize muscle proteins in human epiretinal membranes (ERMs). In the current study, we…”
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18
Myo/Nog cells expressing muscle proteins are present in preretinal membranes from patients with proliferative vitreoretinopathy
Published in Experimental eye research (01-08-2020)“…Proliferative vitreoretinopathy (PVR) is a complication of rhegmatogenous retinal detachment and ocular trauma. The disease is characterized by development of…”
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Resistance of photoreceptors in the C57BL/6-c2J, C57BL/6J, and BALB/cJ mouse strains to oxygen stress: Evidence of an oxygen phenotype
Published in Current eye research (01-01-2004)“…Purpose. To assess the vulnerability of retinal photoreceptors in the BALB/cJ, C57BL/6J, and C57BL/6-c2J (c2J) mouse strains to hypoxic and hyperoxic stress…”
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Neuroprotective Role of Hyperoxia During the Critical Period of Retinal Development in Normal Mice and Mice with Retinitis Pigmentosa
Published in The FASEB journal (01-05-2022)“…Background The retina utilizes more oxygen than any other tissue in the body. Photoreceptors located in the retina's outer nuclear layer (ONL) are culled…”
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