Search Results - "Bravo, J."

Direct reprogramming of human neural stem cells by OCT4 by Schöler, Hans R, Kim, Jeong Beom, Greber, Boris, Araúzo-Bravo, Marcos J, Meyer, Johann, Park, Kook In, Zaehres, Holm

“…Induced pluripotent stem (iPS) cells have been generated from mouse and human somatic cells by ectopic expression of four transcription factors (OCT4 (also…”
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Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages by Ohnishi, Yusuke, Huber, Wolfgang, Tsumura, Akiko, Kang, Minjung, Xenopoulos, Panagiotis, Kurimoto, Kazuki, Oleś, Andrzej K., Araúzo-Bravo, Marcos J., Saitou, Mitinori, Hadjantonakis, Anna-Katerina, Hiiragi, Takashi

“…It is now recognized that extensive expression heterogeneities among cells precede the emergence of lineages in the early mammalian embryo. To establish a map…”
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Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis by Song, Guangqi, Pacher, Martin, Balakrishnan, Asha, Yuan, Qinggong, Tsay, Hsin-Chieh, Yang, Dakai, Reetz, Julia, Brandes, Sabine, Dai, Zhen, Pützer, Brigitte M., Araúzo-Bravo, Marcos J., Steinemann, Doris, Luedde, Tom, Schwabe, Robert F., Manns, Michael P., Schöler, Hans R., Schambach, Axel, Cantz, Tobias, Ott, Michael, Sharma, Amar Deep

“…Direct induction of induced hepatocytes (iHeps) from fibroblasts holds potential as a strategy for regenerative medicine but until now has only been shown in…”
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Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors by Han, Dong Wook, Tapia, Natalia, Hermann, Andreas, Hemmer, Kathrin, Höing, Susanne, Araúzo-Bravo, Marcos J., Zaehres, Holm, Wu, Guangming, Frank, Stefan, Moritz, Sören, Greber, Boris, Yang, Ji Hun, Lee, Hoon Taek, Schwamborn, Jens C., Storch, Alexander, Schöler, Hans R.

“…Recent studies have shown that defined sets of transcription factors can directly reprogram differentiated somatic cells to a different differentiated cell…”
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Quantum emitters near a metal nanoparticle: strong coupling and quenching by Delga, A, Feist, J, Bravo-Abad, J, Garcia-Vidal, F J

“…We investigate the interplay between quenching and strong coupling in systems that include a collection of quantum emitters interacting with a metal…”
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A mechanism for the segregation of age in mammalian neural stem cells by Moore, D. L., Pilz, G. A., Araúzo-Bravo, M. J., Barral, Y., Jessberger, S.

“…Throughout life, neural stem cells (NSCs) generate neurons in the mammalian brain. Using photobleaching experiments, we found that during cell division in…”
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Has health in Spain been declining since the economic crisis? by Regidor, Enrique, Barrio, Gregorio, Bravo, María J, de la Fuente, Luis

“…Background The economic recession starting in 2008 may be having negative effects on health. Purpose We aimed to identify and characterise changes in trends in…”
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Early spectra of the gravitational wave source GW170817: Evolution of a neutron star merger by Shappee, B. J., Simon, J. D., Drout, M. R., Piro, A. L., Morrell, N., Prieto, J. L., Kasen, D., Holoien, T. W.-S., Kollmeier, J. A., Kelson, D. D., Coulter, D. A., Foley, R. J., Kilpatrick, C. D., Siebert, M. R., Madore, B. F., Murguia-Berthier, A., Pan, Y.-C., Prochaska, J. X., Ramirez-Ruiz, E., Rest, A., Adams, C., Alatalo, K., Bañados, E., Baughman, J., Bernstein, R. A., Bitsakis, T., Boutsia, K., Bravo, J. R., Di Mille, F., Higgs, C. R., Ji, A. P., Maravelias, G., Marshall, J. L., Placco, V. M., Prieto, G., Wan, Z.

“…On 17 August 2017, Swope Supernova Survey 2017a (SSS17a) was discovered as the optical counterpart of the binary neutron star gravitational wave event…”
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Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile by Sugawa, Fumihiro, Araúzo-Bravo, Marcos J, Yoon, Juyong, Kim, Kee-Pyo, Aramaki, Shinya, Wu, Guangming, Stehling, Martin, Psathaki, Olympia E, Hübner, Karin, Schöler, Hans R

“…Primordial germ cells (PGCs) develop only into sperm and oocytes in vivo . The molecular mechanisms underlying human PGC specification are poorly understood…”
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Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling by Haling, Jacob R., Sudhamsu, Jawahar, Yen, Ivana, Sideris, Steve, Sandoval, Wendy, Phung, Wilson, Bravo, Brandon J., Giannetti, Anthony M., Peck, Ariana, Masselot, Alexandre, Morales, Tony, Smith, Darin, Brandhuber, Barbara J., Hymowitz, Sarah G., Malek, Shiva

“…Numerous oncogenic mutations occur within the BRAF kinase domain (BRAFKD). Here we show that stable BRAF-MEK1 complexes are enriched in BRAFWT and KRAS mutant…”
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Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis by Knobloch, Marlen, Braun, Simon M. G., Zurkirchen, Luis, von Schoultz, Carolin, Zamboni, Nicola, Araúzo-Bravo, Marcos J., Kovacs, Werner J., Karalay, Özlem, Suter, Ueli, Machado, Raquel A. C., Roccio, Marta, Lutolf, Matthias P., Semenkovich, Clay F., Jessberger, Sebastian

“…Adult neural stem and progenitor cells (NSPCs) show high levels of fatty acid synthase (Fasn)-dependent de novo lipogenesis, a process that is controlled by…”
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Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation by Roh-Johnson, M, Bravo-Cordero, J J, Patsialou, A, Sharma, V P, Guo, P, Liu, H, Hodgson, L, Condeelis, J

“…Most cancer patients die as a result of metastasis, thus it is important to understand the molecular mechanisms of dissemination, including intra- and…”
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Skeletal Muscles of Sedentary and Physically Active Aged People Have Distinctive Genic Extrachromosomal Circular DNA Profiles by Gerovska, Daniela, Araúzo-Bravo, Marcos J

“…To bring new extrachromosomal circular DNA (eccDNA) enrichment technologies closer to the clinic, specifically for screening, early diagnosis, and monitoring…”
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RNA-sequencing from single nuclei by Grindberg, Rashel V., Yee-Greenbaum, Joyclyn L., McConnell, Michael J., Novotny, Mark, O'Shaughnessy, Andy L., Lambert, Georgina M., Araúzo-Bravo, Marcos J., Lee, Jun, Fishman, Max, Robbins, Gillian E., Lin, Xiaoying, Venepally, Pratap, Badger, Jonathan H., Galbraith, David W., Gage, Fred H., Lasken, Roger S.

“…It has recently been established that synthesis of double-stranded cDNA can be done from a single cell for use in DNA sequencing. Global gene expression can be…”
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Review article: intestinal barrier dysfunction and central nervous system disorders – a controversial association by Julio‐Pieper, M., Bravo, J. A., Aliaga, E., Gotteland, M.

“…Summary Background Central nervous system (CNS) development and physiopathology are greatly affected by environmental stimuli. The intestinal barrier restricts…”
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DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism by Sharifi-Zarchi, Ali, Gerovska, Daniela, Adachi, Kenjiro, Totonchi, Mehdi, Pezeshk, Hamid, Taft, Ryan J, Schöler, Hans R, Chitsaz, Hamidreza, Sadeghi, Mehdi, Baharvand, Hossein, Araúzo-Bravo, Marcos J

“…DNA methylation at promoters is largely correlated with inhibition of gene expression. However, the role of DNA methylation at enhancers is not fully…”
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Human Dermal Fibroblast Subpopulations Are Conserved across Single-Cell RNA Sequencing Studies by Ascensión, Alex M., Fuertes-Álvarez, Sandra, Ibañez-Solé, Olga, Izeta, Ander, Araúzo-Bravo, Marcos J.

“…On the basis of their differential location within the dermis and of discrete changes in gene and protein expression, two major fibroblast subtypes (papillary…”
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Targeting liver sinusoidal endothelial cells with miR‐20a‐loaded nanoparticles reduces murine colon cancer metastasis to the liver by Marquez, Joana, Fernandez‐Piñeiro, Ines, Araúzo‐Bravo, Marcos J., Poschmann, Gereon, Stühler, Kai, Khatib, Abdel‐Majid, Sanchez, Alejandro, Unda, Fernando, Ibarretxe, Gaskon, Bernales, Irantzu, Badiola, Iker

“…Phenotypic transformation of liver sinusoidal endothelial cells is one of the most important stages of liver metastasis progression. The miRNA effects on liver…”
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Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo by Dong, S., Aguirre-Hernandez, C., Scrivo, A., Eliscovich, C., Arias, E., Bravo-Cordero, J. J., Cuervo, A. M.

“…Autophagy malfunctioning occurs in multiple human disorders, making attractive the idea of chemically modulating it with therapeutic purposes. However, for…”
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Direct Induction of Trophoblast Stem Cells from Murine Fibroblasts by Kubaczka, Caroline, Senner, Claire E., Cierlitza, Monika, Araúzo-Bravo, Marcos J., Kuckenberg, Peter, Peitz, Michael, Hemberger, Myriam, Schorle, Hubert

“…Trophoblast stem cells (TSCs) arise from the first cell fate decision in the developing embryo and generate extra-embryonic lineages, giving rise to the fetal…”
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