Search Results - "Bravenboer, Nathalie"

Collagen transport and related pathways in Osteogenesis Imperfecta by Claeys, Lauria, Storoni, Silvia, Eekhoff, Marelise, Elting, Mariet, Wisse, Lisanne, Pals, Gerard, Bravenboer, Nathalie, Maugeri, Alessandra, Micha, Dimitra

“…Osteogenesis Imperfecta (OI) comprises a heterogeneous group of patients who share bone fragility and deformities as the main characteristics, albeit with…”
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The Osteocyte as the New Discovery of Therapeutic Options in Rare Bone Diseases by Pathak, Janak L., Bravenboer, Nathalie, Klein-Nulend, Jenneke

“…Osteocytes are the most abundant (~95%) cells in bone with the longest half-life (~25 years) in humans. In the past osteocytes have been regarded as vestigial…”
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Editorial: Rare musculoskeletal disorders: disease mechanisms and therapies by Seefried, Lothar, Bravenboer, Nathalie, Imel, Erik A

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Bone Tissue Regeneration in the Oral and Maxillofacial Region: A Review on the Application of Stem Cells and New Strategies to Improve Vascularization by Schulten, Engelbert A. J. M., Jin, Jianfeng, ten Bruggenkate, Christiaan M., Bravenboer, Nathalie, Helder, Marco N., Wu, Vivian, Klein-Nulend, Jenneke

“…Bone tissue engineering techniques are a promising alternative for the use of autologous bone grafts to reconstruct bone defects in the oral and maxillofacial…”
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A Three-Dimensional Mechanical Loading Model of Human Osteocytes in Their Native Matrix by Zhang, Chen, Farré-Guasch, Elisabet, Jin, Jianfeng, van Essen, Huib W., Klein-Nulend, Jenneke, Bravenboer, Nathalie

“…Osteocytes are mechanosensory cells which are embedded in calcified collagenous matrix. The specific native matrix of osteocytes affects their regulatory…”
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Mechanical loading modulates phosphate related genes in rat bone by Nepal, Ashwini Kumar, van Essen, Hubertus W, Reijnders, Christianne M A, Lips, Paul, Bravenboer, Nathalie

“…Mechanical loading determines bone mass and bone structure, which involves many biochemical signal molecules. Of these molecules, Mepe and Fgf23 are involved…”
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Human Fibroblasts as a Model for the Study of Bone Disorders by Claeys, Lauria, Bravenboer, Nathalie, Eekhoff, Elisabeth M W, Micha, Dimitra

“…Bone tissue degeneration is an urgent clinical issue, making it a subject of intensive research. Chronic skeletal disease forms can be prevalent, such as the…”
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In Vitro Modelling of Osteogenesis Imperfecta with Patient-Derived Induced Mesenchymal Stem Cells by Claeys, Lauria, Zhytnik, Lidiia, Ventura, Laura, Wisse, Lisanne E, Eekhoff, Elisabeth M W, Pals, Gerard, Bravenboer, Nathalie, Heine, Vivi M, Micha, Dimitra

“…(1) Mesenchymal stem cells (MSCs) are a valuable cell model to study the bone pathology of Osteogenesis Imperfecta (OI), a rare genetic collagen-related…”
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Editorial: Bone Marrow Adiposity: Establishing Harmonized, Mechanistic, and Multidisciplinary Approaches to Reach Clinical Translation by Lucas, Stephanie, Rosen, Clifford James, Bravenboer, Nathalie

“…This Research Topic comprises ten articles describing different approaches to study the regulation or maturation of bone marrow adiposity. The conversion of…”
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Systemic Inflammation Affects Human Osteocyte-Specific Protein and Cytokine Expression by Pathak, Janak L., Bakker, Astrid D., Luyten, Frank P., Verschueren, Patrick, Lems, Willem F., Klein-Nulend, Jenneke, Bravenboer, Nathalie

“…Bone remodeling can be disturbed in active rheumatoid arthritis (RA), possibly as a result of elevated levels of circulating inflammatory cytokines…”
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K-Carrageenan Stimulates Pre-Osteoblast Proliferation and Osteogenic Differentiation: A Potential Factor for the Promotion of Bone Regeneration? by Cao, Wei, Jin, Jianfeng, Wu, Gang, Bravenboer, Nathalie, Helder, Marco N., Pathak, Janak L., Zandieh-Doulabi, Behrouz, Hogervorst, Jolanda M. A., Matsukawa, Shingo, Geonzon, Lester C., Bacabac, Rommel G., Schulten, Engelbert A. J. M., Klein-Nulend, Jenneke

“…Current cell-based bone tissue regeneration strategies cannot cover large bone defects. K-carrageenan is a highly hydrophilic and biocompatible seaweed-derived…”
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Osteogenic transdifferentiation of primary human fibroblasts to osteoblast-like cells with human platelet lysate by Cayami, Ferdy K., Claeys, Lauria, de Ruiter, Ruben, Smilde, Bernard J., Wisse, Lisanne, Bogunovic, Natalija, Riesebos, Elise, Eken, Lyra, Kooi, Irsan, Sistermans, Erik A., Bravenboer, Nathalie, Pals, Gerard, Faradz, Sultana M. H., Sie, Daoud, Eekhoff, E. Marelise W., Micha, Dimitra

“…Inherited bone disorders account for about 10% of documented Mendelian disorders and are associated with high financial burden. Their study requires…”
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The Effect of Sclerostin and Monoclonal Sclerostin Antibody Romosozumab on Osteogenesis and Osteoclastogenesis Mediated by Periodontal Ligament Fibroblasts by Pigeaud, Karina E, Rietveld, Melanie L, Witvliet, Aster F, Hogervorst, Jolanda M A, Zhang, Chen, Forouzanfar, Tim, Bravenboer, Nathalie, Schoenmaker, Ton, de Vries, Teun J

“…Sclerostin is a bone formation inhibitor produced by osteocytes. Although sclerostin is mainly expressed in osteocytes, it was also reported in periodontal…”
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Blood Vessel Formation and Bone Regeneration Potential of the Stromal Vascular Fraction Seeded on a Calcium Phosphate Scaffold in the Human Maxillary Sinus Floor Elevation Model by Farré-Guasch, Elisabet, Bravenboer, Nathalie, Helder, Marco N, Schulten, Engelbert A J M, Ten Bruggenkate, Christiaan M, Klein-Nulend, Jenneke

“…Bone substitutes are used as alternatives for autologous bone grafts in patients undergoing maxillary sinus floor elevation (MSFE) for dental implant…”
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[18F]NaF PET/CT scan as an early marker of heterotopic ossification in fibrodysplasia ossificans progressiva by Eekhoff, E. Marelise W., Botman, Esmée, Coen Netelenbos, J., de Graaf, Pim, Bravenboer, Nathalie, Micha, Dimitra, Pals, Gerard, de Vries, Teun J., Schoenmaker, Ton, Hoebink, Max, Lammertsma, Adriaan A., Raijmakers, Pieter G.H.M.

“…Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease with a progressive course characterized by episodically local flare-ups, which often but…”
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Cytokines TNF-α, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells by Bastidas-Coral, Angela P., Bakker, Astrid D., Zandieh-Doulabi, Behrouz, Kleverlaan, Cornelis J., Bravenboer, Nathalie, Forouzanfar, Tim, Klein-Nulend, Jenneke

“…During the initial stages of bone repair, proinflammatory cytokines are released within the injury site, quickly followed by a shift to anti-inflammatory…”
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Gender- and Age-Associated Differences in Bone Marrow Adipose Tissue and Bone Marrow Fat Unsaturation Throughout the Skeleton, Quantified Using Chemical Shift Encoding-Based Water-Fat MRI by Beekman, Kerensa M, Regenboog, Martine, Nederveen, Aart J, Bravenboer, Nathalie, den Heijer, Martin, Bisschop, Peter H, Hollak, Carla E, Akkerman, Erik M, Maas, Mario

“…Bone marrow adipose tissue (BMAT) is a dynamic tissue which is associated with osteoporosis, bone metastasis, and primary bone tumors. The aim of this study is…”
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The intricate mechanism of PLS3 in bone homeostasis and disease by Zhong, Wenchao, Pathak, Janak L, Liang, Yueting, Zhytnik, Lidiia, Pals, Gerard, Eekhoff, Elisabeth M W, Bravenboer, Nathalie, Micha, Dimitra

“…Since our discovery in 2013 that genetic defects in lead to bone fragility, the mechanistic details of this process have remained obscure. It has been…”
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Increased Bone Resorption during Lactation in Pycnodysostosis by Jansen, Ineke D C, Papapoulos, Socrates E, Bravenboer, Nathalie, de Vries, Teun J, Appelman-Dijkstra, Natasha M

“…Pycnodysostosis, a rare autosomal recessive skeletal dysplasia, is caused by a deficiency of cathepsin K. Patients have impaired bone resorption in the…”
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CXCL8 and CCL20 Enhance Osteoclastogenesis via Modulation of Cytokine Production by Human Primary Osteoblasts by Pathak, Janak L, Bakker, Astrid D, Verschueren, Patrick, Lems, Willem F, Luyten, Frank P, Klein-Nulend, Jenneke, Bravenboer, Nathalie

“…Generalized osteoporosis is common in patients with inflammatory diseases, possibly because of circulating inflammatory factors that affect osteoblast and…”
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