Search Results - "Braun, Lukas"
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Interfacial Self‐Assembly of Amphiphilic Dual Temperature Responsive Actuating Janus Particles
Published in Advanced functional materials (24-05-2018)“…Amphiphilic Janus particles feature the combination of two different functional materials in one single colloid, as well as the possibility of self‐assembly at…”
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2
Kinase Inhibition as Treatment for Acute and Chronic Graft- Versus -Host Disease
Published in Frontiers in immunology (17-11-2021)“…Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a potentially curative therapy for patients suffering from hematological malignancies the…”
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3
Functional liquid crystalline particles and beyond
Published in Liquid crystals (14-11-2019)“…Recently the preparation and handling of liquid crystalline (LC) particles, which cover the size from some 100 nano-meters to micro- and millimetres found more…”
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4
Ultrafast photocurrents at the surface of the three-dimensional topological insulator Bi2Se3
Published in Nature communications (31-10-2016)“…Three-dimensional topological insulators are fascinating materials with insulating bulk yet metallic surfaces that host highly mobile charge carriers with…”
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5
Influences of Ortho‐Fluoroazobenzenes on Liquid Crystalline Phase Stability and 2D (Planar) Actuation Properties of Liquid Crystalline Elastomers
Published in Macromolecular chemistry and physics (01-01-2020)“…In this article, the influences of ortho‐fluoroazobenzenes (o‐Fbs) on liquid crystalline (LC) phase stability and actuation properties of liquid crystalline…”
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6
Tuning the Magnetic Anisotropy of Single Molecules
Published in Nano letters (10-06-2015)“…The magnetism of single atoms and molecules is governed by the atomic scale environment. In general, the reduced symmetry of the surrounding splits the d…”
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7
Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect
Published in Haematologica (Roma) (01-08-2021)“…Acute graft-versus-host disease causes significant mortality in patients undergoing allogeneic hematopoietic cell transplantation. Immunosuppressive treatment…”
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8
Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control
Published in Nature communications (31-01-2018)“…Most systemic viral gene therapies have been limited by sequestration and degradation of virions, innate and adaptive immunity, and silencing of therapeutic…”
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Immunomodulatory Therapies for the Treatment of Graft‐versus‐host Disease
Published in HemaSphere (01-06-2021)“…Allogeneic hematopoietic stem cell transplantation (allo‐HCT) is a potentially curative therapy for patients suffering from hematological malignancies, and its…”
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10
Immunotherapy in Myeloproliferative Diseases
Published in Cells (Basel, Switzerland) (26-06-2020)“…Myeloproliferative diseases, including myeloproliferative neoplasms (MPN) and myelodysplastic syndromes (MDS), are driven by genetic abnormalities and…”
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Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer
Published in Cancer letters (10-07-2022)“…Metastatic small cell lung cancer (SCLC) is not curable. While SCLC is initially sensitive to chemotherapy, remissions are short-lived. The relapse is induced…”
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Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation
Published in Blood (08-09-2022)“…Patients with acute myeloid leukemia (AML) often achieve remission after allogeneic hematopoietic cell transplantation (allo-HCT) but subsequently die of…”
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13
Influence of a Crosslinker Containing an Azo Group on the Actuation Properties of a Photoactuating LCE System
Published in Polymers (14-12-2016)“…Photoactuating liquid crystalline elastomers (LCE) are promising candidates for an application as artificial muscles in microdevices. In this work, we…”
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14
COVID‐19‐associated pulmonary aspergillosis in ICU patients in a German reference centre: Phenotypic and molecular characterisation of Aspergillus fumigatus isolates
Published in Mycoses (01-04-2022)“…Background COVID‐19‐associated invasive pulmonary aspergillosis (CAPA) is associated with increased mortality. Cases of CAPA caused by azole‐resistant…”
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15
Unraveling altered RNA metabolism in pancreatic cancer cells by liquid-chromatography coupling to ion mobility mass spectrometry
Published in Analytical and bioanalytical chemistry (01-09-2019)“…Ion mobility coupling to mass spectrometry facilitates enhanced identification certitude. Further coupling to liquid chromatography results in…”
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Plasma biomarkers for prediction of early tumor recurrence after resection of pancreatic ductal adenocarcinoma
Published in Scientific reports (05-04-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is a disease with a very unfavorable prognosis. Surgical resection represents the only potentially curative treatment…”
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17
MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production
Published in Molecular cancer research (01-08-2023)“…The treatment of patients with metastatic melanoma with immune checkpoint inhibitors (ICI) leads to impressive response rates but primary and secondary…”
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Oncogenic KrasG12D Activation in the Nonhematopoietic Bone Marrow Microenvironment Causes Myelodysplastic Syndrome in Mice
Published in Molecular cancer research (01-09-2021)“…Abstract The bone marrow microenvironment (BMME) is key player in regulation and maintenance of hematopoiesis. Oncogenic RAS mutations, causing constitutive…”
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Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling
Published in Science translational medicine (21-12-2022)“…Acute graft-versus-host disease (aGVHD), which is driven by allogeneic T cells, has a high mortality rate and limited treatment options. Human β-defensin 2…”
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Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti-TIM-3 therapy in mice
Published in The Journal of clinical investigation (15-08-2024)“…Leukemia relapse is a major cause of death after allogeneic hematopoietic cell transplantation (allo-HCT). We tested the potential of targeting T cell (Tc)…”
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