Search Results - "Braun, Kristin M."

Constitutive Autophagy and Nucleophagy during Epidermal Differentiation by Akinduro, Olufolake, Sully, Katherine, Patel, Ankit, Robinson, Deborah J., Chikh, Anissa, McPhail, Graham, Braun, Kristin M., Philpott, Michael P., Harwood, Catherine A., Byrne, Carolyn, O'Shaughnessy, Ryan F.L., Bergamaschi, Daniele

“…Epidermal keratinocytes migrate through the epidermis up to the granular layer where, on terminal differentiation, they progressively lose organelles and…”
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iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia by Chikh, Anissa, Matin, Rubeta N H, Senatore, Valentina, Hufbauer, Martin, Lavery, Danielle, Raimondi, Claudio, Ostano, Paola, Mello-Grand, Maurizia, Ghimenti, Chiara, Bahta, Adiam, Khalaf, Sahira, Akgül, Baki, Braun, Kristin M, Chiorino, Giovanna, Philpott, Michael P, Harwood, Catherine A, Bergamaschi, Daniele

“…iASPP, an inhibitory member of the ASPP (apoptosis stimulating protein of p53) family, is an evolutionarily conserved inhibitor of p53 which is frequently…”
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Characterization of the Growth of Chlamydia trachomatis in In Vitro -Generated Stratified Epithelium by Nogueira, Ana T, Braun, Kristin M, Carabeo, Rey A

“…infection targets the mucosal epithelium, where squamous and columnar epithelia can be found. Research on -epithelia interaction has predominantly focused on…”
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Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis by Braun, K M, Niemann, C, Jensen, U B, Sundberg, J P, Silva-Vargas, V, Watt, F M

“…Mammalian epidermis is maintained by stem cells that have the ability to self-renew and generate daughter cells that differentiate along the lineages of the…”
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The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells by Nijhof, Joanne G W, Braun, Kristin M, Giangreco, Adam, van Pelt, Carina, Kawamoto, Hiroshi, Boyd, Richard L, Willemze, Rein, Mullenders, Leon H F, Watt, Fiona M, de Gruijl, Frank R, van Ewijk, Willem

“…We describe a novel murine progenitor cell population localised to a previously uncharacterised region between sebaceous glands and the hair follicle bulge,…”
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Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility by Theocharidis, Georgios, Drymoussi, Zoe, Kao, Alexander P., Barber, Asa H., Lee, David A., Braun, Kristin M., Connelly, John T.

“…Type VI collagen is a nonfibrillar collagen expressed in many connective tissues and implicated in extracellular matrix (ECM) organization. We hypothesized…”
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Rac1 deletion causes thymic atrophy by Hunziker, Lukas, Benitah, Salvador Aznar, Aznar Benitah, Salvador, Braun, Kristin M, Jensen, Kim, McNulty, Katrina, Butler, Colin, Potton, Elspeth, Nye, Emma, Boyd, Richard, Laurent, Geoff, Glogauer, Michael, Wright, Nick A, Watt, Fiona M, Janes, Sam M

“…The thymic stroma supports T lymphocyte development and consists of an epithelium maintained by thymic epithelial progenitors. The molecular pathways that…”
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Investigating wound healing characteristics of gingival and skin keratinocytes in organotypic cultures by Smith, Chris J., Parkinson, Eric K., Yang, Jingjuin, Pratten, Jonathan, O'Toole, Edel A., Caley, Matthew P., Braun, Kristin M.

“…•Gingival junctional epithelium is recapitulated using a novel 3D organotypic method.•Gingival models re-epithelialize faster than skin in the 2D and 3D…”
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Distinct epidermal stem cell compartments are maintained by independent niche microenvironments by Braun, Kristin M, Prowse, David M

“…The mammalian epidermis is a stratified, multilayered epithelium, consisting of the interfollicular epidermis and associated appendages, which extend into the…”
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Correction: Rac1 Deletion Causes Thymic Atrophy by Hunziker, Lukas, Aznar Benitah, Salvador, Braun, Kristin M., Jensen, Kim, McNulty, Katrina, Butler, Colin, Potton, Elspeth, Nye, Emma, Boyd, Richard, Laurent, Geoff, Glogauer, Michael, Wright, Nick A., Watt, Fiona M., Janes, Sam M.

“…Competing interests: No competing interests declared…”
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Hepatocyte transplantation in a model of toxin-induced liver disease: variable therapeutic effect during replacement of damaged parenchyma by donor cells by Sandgren, Eric P, Braun, Kristin M, Degen, Jay L

“…To provide long-term therapy in patients with severe toxin-induced hepatic parenchymal damage, donor hepatocytes would need to replicate and replace a large…”
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Characterization of Bipotential Epidermal Progenitors Derived from Human Sebaceous Gland: Contrasting Roles of c‐Myc and β‐Catenin by Lo Celso, Cristina, Berta, Melanie A., Braun, Kristin M., Frye, Michaela, Lyle, Stephen, Zouboulis, Christos C., Watt, Fiona M.

“…The current belief is that the epidermal sebaceous gland (SG) is maintained by unipotent stem cells that are replenished by multipotent stem cells in the hair…”
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Hepatic Microenvironment Affects Oval Cell Localization in Albumin-Urokinase-Type Plasminogen Activator Transgenic Mice by Braun, Kristin M., Thompson, Anne W., Sandgren, Eric P.

“…Mice carrying an albumin-urokinase type plasminogen activator transgene (AL-uPA) develop liver disease secondary to uPA expression in hepatocytes…”
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Recessive Mutation in FAM83G Associated with Palmoplantar Keratoderma and Exuberant Scalp Hair by Maruthappu, Thiviyani, McGinty, Lisa A., Blaydon, Diana C., Fell, Benjamin, Määttä, Arto, Duit, Rebecca, Hawkins, Tim, Braun, Kristin M., Simpson, Michael A., O’Toole, Edel A., Kelsell, David P.

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β-Catenin and Hedgehog Signal Strength Can Specify Number and Location of Hair Follicles in Adult Epidermis without Recruitment of Bulge Stem Cells by Silva-Vargas, Violeta, Lo Celso, Cristina, Giangreco, Adam, Ofstad, Tyler, Prowse, David M., Braun, Kristin M., Watt, Fiona M.

“…Using K14ΔNβ-cateninER transgenic mice, we show that short-term, low-level β-catenin activation stimulates de novo hair follicle formation from sebaceous…”
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Cutaneous cancer stem cells: beta-catenin strikes again by Braun, Kristin M

“…Cancer stem cells (CSCs) are a subpopulation of tumor cells that retain properties of tissue-specific stem cells, including the ability to self-renew. In a…”
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Epidermal label-retaining cells: background and recent applications by Braun, Kristin M, Watt, Fiona M

“…Epidermal label-retaining cells (LRC) can be identified by giving neonatal mice repeated injections of 3H-thymidine or 5-bromo-2'-deoxyuridine and then finding…”
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Bone marrow cells engraft within the epidermis and proliferate in vivo with no evidence of cell fusion by Brittan, Mairi, Braun, Kristin M, Reynolds, Louise E, Conti, Francesco J, Reynolds, Andrew R, Poulsom, Richard, Alison, Malcolm R, Wright, Nicholas A, Hodivala-Dilke, Kairbaan M

“…In adults, bone marrow‐derived cells (BMDC) can contribute to the structure of various non‐haematopoietic tissues, including skin. However, the physiological…”
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Functional characterization of highly adherent CD34+ keratinocytes isolated from human skin by Gutiérrez-Rivera, Araika, Pavón-Rodríguez, Andrés, Jiménez-Acosta, Francisco, Poblet, Enrique, Braun, Kristin M., Cormenzana, Pedro, Ciria, Juan Pablo, Larretxea, Rafael, Cárdenas, José Manuel, Izeta, Ander

“…Please cite this paper as: Functional characterization of highly adherent CD34+ keratinocytes isolated from human skin. Experimental Dermatology 2010; 19:…”
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Characterizing the phenotype of murine epidermal progenitor cells: complementary whole-mount visualization and flow cytometry strategies by Henseleit, Korinna D, Wheeler, Ann P, Warnes, Gary, Braun, Kristin M

“…The epidermis and its appendages, the hair follicle and sebaceous gland, have the capacity to constantly regenerate throughout adult life. Postnatal hair…”
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