Search Results - "Braun, Kees P"
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Functional and structural brain networks in epilepsy: What have we learned?
Published in Epilepsia (Copenhagen) (01-11-2013)“…Summary Brain functioning is increasingly seen as a complex interplay of dynamic neural systems that rely on the integrity of structural and functional…”
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Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis
Published in Lancet neurology (01-07-2017)“…Summary Background People with epilepsy who became seizure-free while taking antiepileptic drugs might consider discontinuing their medication, with the…”
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3
Brain Network Organization in Focal Epilepsy: A Systematic Review and Meta-Analysis
Published in PloS one (10-12-2014)“…Normal brain functioning is presumed to depend upon interacting regions within large-scale neuronal networks. Increasing evidence exists that interictal…”
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Reappraisal of the Medical Research Council Antiepileptic Drug Withdrawal Study: Contamination‐adjusted and dose‐response re‐analysis
Published in Epilepsia (Copenhagen) (01-07-2022)“…Objective The 1991 Medical Research Council (MRC) Study compared seizure relapse for seizure‐free patients randomized to withdraw vs continue of antiseizure…”
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Update on Drug Management of Refractory Epilepsy in Tuberous Sclerosis Complex
Published in Paediatric drugs (01-02-2020)“…Tuberous sclerosis complex (TSC) is a genetic neurocutaneous disorder with epilepsy as a common and early presenting symptom. The neurological phenotype,…”
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Deprescribing in Epilepsy: Do No Harm
Published in JAMA neurology (01-06-2020)Get more information
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A meta-analysis of white matter changes in temporal lobe epilepsy as studied with diffusion tensor imaging
Published in Epilepsia (Copenhagen) (01-04-2012)“…Summary Purpose: Diffusion tensor imaging (DTI) is used increasingly to study white matter integrity in people with temporal lobe epilepsy (TLE). Most studies…”
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NaV1.1 and NaV1.6 selective compounds reduce the behavior phenotype and epileptiform activity in a novel zebrafish model for Dravet Syndrome
Published in PloS one (05-03-2020)“…Dravet syndrome is caused by dominant loss-of-function mutations in SCN1A which cause reduced activity of Nav1.1 leading to lack of neuronal inhibition. On the…”
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Intelligence quotient improves after antiepileptic drug withdrawal following pediatric epilepsy surgery
Published in Annals of neurology (01-07-2015)“…Objective Antiepileptic drugs (AEDs) have cognitive side effects that, particularly in children, may affect intellectual functioning. With the TimeToStop (TTS)…”
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Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study
Published in Lancet neurology (01-09-2012)“…Summary Background Postoperative antiepileptic drug (AED) withdrawal practices remain debatable and little is known about the optimum timing. We hypothesised…”
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A Comparative Study of SMN Protein and mRNA in Blood and Fibroblasts in Patients with Spinal Muscular Atrophy and Healthy Controls
Published in PloS one (28-11-2016)“…Clinical trials to test safety and efficacy of drugs for patients with spinal muscular atrophy (SMA) are currently underway. Biomarkers that document…”
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Improved diagnosis in children with partial epilepsy using a multivariable prediction model based on EEG network characteristics
Published in PloS one (02-04-2013)“…Electroencephalogram (EEG) acquisition is routinely performed to support an epileptic origin of paroxysmal events in patients referred with a possible…”
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Tailoring epilepsy surgery with fast ripples in the intraoperative electrocorticogram
Published in Annals of neurology (01-05-2017)“…Objective Intraoperative electrocorticography (ECoG) can be used to delineate the resection area in epilepsy surgery. High‐frequency oscillations (HFOs; 80–500…”
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Incidence of and predictors for antiseizure medication gaps in Medicare beneficiaries with epilepsy: a retrospective cohort study
Published in BMC neurology (01-09-2022)“…For the two-thirds of patients with epilepsy who achieve seizure remission on antiseizure medications (ASMs), patients and clinicians must weigh the pros and…”
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Exit Strategy: Balancing the Risks and Rewards of Antiseizure Medication Withdrawal
Published in Epilepsy Currents (01-06-2024)“…The majority of people with epilepsy achieves long-term seizure-freedom and may consider withdrawal of their anti-seizure medications (ASMs). Withdrawal of…”
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Treatment of electrical status epilepticus in sleep: A pooled analysis of 575 cases
Published in Epilepsia (Copenhagen) (01-11-2015)“…Summary Objective Epileptic encephalopathy with electrical status epilepticus in sleep (ESES) is a pediatric epilepsy syndrome with sleep‐induced epileptic…”
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Ripples on rolandic spikes: A marker of epilepsy severity
Published in Epilepsia (Copenhagen) (01-07-2016)“…Summary Objective Children with rolandic spikes may or may not have seizures, ranging from benign rolandic epilepsy to severe atypical rolandic epilepsy. We…”
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Physiological Ripples (± 100 Hz) in Spike-Free Scalp EEGs of Children With and Without Epilepsy
Published in Brain topography (01-11-2017)“…Pathological high frequency oscillations (HFOs, >80 Hz) are considered new biomarkers for epilepsy. They have mostly been recorded invasively, but pathological…”
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Residual fast ripples in the intraoperative corticogram predict epilepsy surgery outcome
Published in Neurology (14-07-2015)“…OBJECTIVE:We studied whether residual high-frequency oscillations (80–500 Hz; ripples, 80–250 Hz), especially fast ripples (FRs, 250–500 Hz), in post-resection…”
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Clinical characteristics and diagnoses of 1213 children referred to a first seizure clinic
Published in Epilepsia open (01-04-2024)“…Objective New‐onset seizure‐like events (SLEs) are common in children, but differentiating between epilepsy and its mimics is challenging. This study provides…”
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