Search Results - "Braun, E"
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GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets
Published in Molecular cell (07-10-2011)“…miRNAs are posttranscriptional regulators of gene expression that associate with Argonaute and GW182 proteins to repress translation and/or promote mRNA…”
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2
Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis
Published in Development (Cambridge) (01-03-2018)“…In the murine testis, self-renewal of spermatogonial stem cells (SSCs) requires glial cell line-derived neurotrophic factor (GDNF) secreted from neighboring…”
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3
Development, implementation and performance of a model predictive controller for packaged air conditioners in small and medium-sized commercial building applications
Published in Energy and buildings (01-11-2018)“…•A complete and low cost MPC solution for small/medium sized commercial buildings was developed.•Handling unmeasured building disturbances for modeling and…”
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4
Germ Cell Migration Across Sertoli Cell Tight Junctions
Published in Science (American Association for the Advancement of Science) (09-11-2012)“…The blood-testis barrier includes strands of tight junctions between somatic Sertoli cells that restricts solutes from crossing the paracellular space,…”
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Pathway to Totipotency: Lessons from Germ Cells
Published in Cell (01-12-2006)“…Oocytes and sperm are some of the most differentiated cells in our bodies, yet they generate all cell types after fertilization. Accumulating evidence suggests…”
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ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility
Published in Scientific reports (14-07-2020)“…Adenosine-to-inosine RNA editing, a fundamental RNA modification, is regulated by adenosine deaminase (AD) domain containing proteins. Within the testis, RNA…”
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A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation
Published in Cell (16-06-2016)“…Long intergenic noncoding RNAs (lincRNAs) are important regulators of gene expression. Although lincRNAs are expressed in immune cells, their functions in…”
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8
Functional Hierarchy and Reversibility Within the Murine Spermatogenic Stem Cell Compartment
Published in Science (American Association for the Advancement of Science) (02-04-2010)“…Stem cells support tissue maintenance by balancing self-renewal and differentiation. In mice, it is believed that a homogeneous stem cell population of single…”
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Blood Pressure in Early Autosomal Dominant Polycystic Kidney Disease
Published in The New England journal of medicine (11-12-2014)“…In patients with autosomal dominant polycystic kidney disease, the rate of increase in total kidney volume was not slowed by lisinopril and telmisartan, as…”
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Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis
Published in Genome research (01-03-2019)“…Transgenesis has been a mainstay of mouse genetics for over 30 yr, providing numerous models of human disease and critical genetic tools in widespread use…”
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11
A comparison of variability in spatiotemporal gait parameters between treadmill and overground walking conditions
Published in Gait & posture (01-01-2016)“…Highlights • Variability in gait parameters may differ between treadmill and overground walking. • We examined stride-to-stride variability with Poincaré…”
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12
Stoichiometric and Nonstoichiometric Hydrates of Brucine
Published in Crystal growth & design (05-10-2016)“…The complex interplay of temperature and water activity (a w)/relative humidity (RH) on the solid form stability and transformation pathways of three hydrates…”
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13
The role of GW182 proteins in miRNA-mediated gene silencing
Published in Advances in experimental medicine and biology (01-01-2013)“…GW182 family proteins are essential for microRNA-mediated gene silencing in animal cells. They are recruited to miRNA targets through direct interactions with…”
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14
Germline stem cells
Published in Cold Spring Harbor perspectives in biology (01-11-2011)“…Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can…”
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15
Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8+ T cell receptor alpha repertoire following allogeneic transplantation
Published in Clinical and experimental immunology (01-06-2016)“…Summary Allogeneic stem cell transplantation is potentially curative, but associated with post‐transplantation complications, including cytomegalovirus (CMV)…”
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16
Angiotensin Blockade in Late Autosomal Dominant Polycystic Kidney Disease
Published in The New England journal of medicine (11-12-2014)“…This trial tested single versus dual inhibition of the renin–angiotensin–aldosterone system in ADPKD. ACE-inhibitor monotherapy controlled blood pressure in…”
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Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids
Published in Development (Cambridge) (15-01-2004)“…Androgen receptor function is required for male embryonic sexual differentiation, pubertal development and the regulation of spermatogenesis in mammals. During…”
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Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF
Published in eLife (31-05-2019)“…Long-term maintenance of spermatogenesis in mammals is supported by GDNF, an essential growth factor required for spermatogonial stem cell (SSC) self-renewal…”
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Durable responses to ibrutinib in patients with relapsed CLL after allogeneic stem cell transplantation
Published in Bone marrow transplantation (Basingstoke) (01-06-2016)“…Ibrutinib, a recently approved inhibitor of Bruton’s tyrosine kinase (BTK), has shown great efficacy in patients with high-risk CLL. Nevertheless, there are…”
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Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas
Published in International journal of cancer (15-10-2012)“…Molecular characterization has been extensively studied in serrated polyps but very little is known in serrated adenocarcinomas (SACs). We analyzed the…”
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