Search Results - "Brault, Jean‐Baptiste"
-
1
RAB6 and dynein drive post‐Golgi apical transport to prevent neuronal progenitor delamination
Published in EMBO reports (06-10-2022)“…Radial glial (RG) cells are the neural stem cells of the developing neocortex. Apical RG (aRG) cells can delaminate to generate basal RG (bRG) cells, a cell…”
Get full text
Journal Article -
2
Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly
Published in Nature communications (10-01-2022)“…Primary microcephaly and megalencephaly are severe brain malformations defined by reduced and increased brain size, respectively. Whether these two pathologies…”
Get full text
Journal Article -
3
CAMSAPs organize an acentrosomal microtubule network from basal varicosities in radial glial cells
Published in The Journal of cell biology (02-08-2021)“…Neurons of the neocortex are generated by stem cells called radial glial cells. These polarized cells extend a short apical process toward the ventricular…”
Get full text
Journal Article -
4
Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development
Published in Current biology (23-09-2019)“…A functional bipolar spindle is essential to segregate chromosomes correctly during mitosis. Across organisms and cell types, spindle architecture should be…”
Get full text
Journal Article -
5
A polarized cell system amenable to subcellular resolution imaging of influenza virus infection
Published in PloS one (25-01-2024)“…The life cycle of influenza A viruses (IAV), and notably intracellular trafficking of the viral genome, depends on multiple interactions with the cellular…”
Get full text
Journal Article -
6
Comparative Analysis Between Flaviviruses Reveals Specific Neural Stem Cell Tropism for Zika Virus in the Mouse Developing Neocortex
Published in EBioMedicine (01-08-2016)“…The recent Zika outbreak in South America and French Polynesia was associated with an epidemic of microcephaly, a disease characterized by a reduced size of…”
Get full text
Journal Article -
7
Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses
Published in The Journal of biological chemistry (02-01-2012)“…Identification and characterization of virus-host interactions are very important steps toward a better understanding of the molecular mechanisms responsible…”
Get full text
Journal Article -
8
A cell fate decision map reveals abundant direct neurogenesis bypassing intermediate progenitors in the human developing neocortex
Published in Nature cell biology (01-05-2024)“…The human neocortex has undergone strong evolutionary expansion, largely due to an increased progenitor population, the basal radial glial cells. These cells…”
Get full text
Journal Article -
9
A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus
Published in Vaccine (12-08-2013)“…Highlights • CHIKV recently reemerged in the Indian Ocean and is spreading through the world. • We designed a MV-CHIKV vaccine able to generate CHIKV…”
Get full text
Journal Article -
10
The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication
Published in Virology (New York, N.Y.) (01-09-2011)“…Abstract The role of the membrane protein (prM/M) in flavivirus life cycle remains unclear. Here, we identified a cellular interactor to the 40-residue-long…”
Get full text
Journal Article -
11
Should I stay or should I go? Neural stem cell anchorage during cerebral cortex development requires the GTPase RAB6 and dynein
Published in M.S. Médecine sciences (01-01-2023)Get more information
Journal Article -
12
The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication
Published in Nucleic acids research (08-07-2024)“…Genome-wide approaches have significantly advanced our knowledge of the repertoire of RNA-binding proteins (RBPs) that associate with cellular polyadenylated…”
Get full text
Journal Article