Search Results - "Braughton, Kevin R. "

Targeting of Alpha-Hemolysin by Active or Passive Immunization Decreases Severity of USA300 Skin Infection in a Mouse Model by Kennedy, Adam D., Wardenburg, Juliane Bubeck, Gardner, Donald J., Long, Daniel, Whitney, Adeline R., Braughton, Kevin R., Schneewind, Olaf, DeLeo, Frank R.

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are predominantly those affecting skin and soft tissues. Although…”
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Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus by Li, Min, Diep, Binh An, Villaruz, Amer E, Braughton, Kevin R, Jiang, Xiaofei, DeLeo, Frank R, Chambers, Henry F, Lu, Yuan, Otto, Michael

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged worldwide. The United States, in particular, is experiencing a…”
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Comparative Analysis of USA300 Virulence Determinants in a Rabbit Model of Skin and Soft Tissue Infection by Kobayashi, Scott D., Malachowa, Natalia, Whitney, Adeline R., Braughton, Kevin R., Gardner, Donald J., Long, Dan, Wardenburg, Juliane Bubeck, Schneewind, Olaf, Otto, Michael, DeLeo, Frank R.

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are frequently associated with strains harboring genes encoding…”
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Global changes in Staphylococcus aureus gene expression in human blood by Malachowa, Natalia, Whitney, Adeline R, Kobayashi, Scott D, Sturdevant, Daniel E, Kennedy, Adam D, Braughton, Kevin R, Shabb, Duncan W, Diep, Binh An, Chambers, Henry F, Otto, Michael, DeLeo, Frank R

“…Staphylococcus aureus is a leading cause of bloodstream infections worldwide. In the United States, many of these infections are caused by a strain known as…”
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Staphylococcus epidermidis strategies to avoid killing by human neutrophils by Cheung, Gordon Y C, Rigby, Kevin, Wang, Rong, Queck, Shu Y, Braughton, Kevin R, Whitney, Adeline R, Teintze, Martin, DeLeo, Frank R, Otto, Michael

“…Staphylococcus epidermidis is a leading nosocomial pathogen. In contrast to its more aggressive relative S. aureus, it causes chronic rather than acute…”
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Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury by Diep, Binh An, Chan, Liana, Tattevin, Pierre, Kajikawa, Osamu, Martin, Thomas R, Basuino, Li, Mai, Thuy T, Marbach, Helene, Braughton, Kevin R, Whitney, Adeline R, Gardner, Donald J, Fan, Xuemo, Tseng, Ching W, Liu, George Y, Badiou, Cedric, Etienne, Jerome, Lina, Gerard, Matthay, Michael A, DeLeo, Frank R, Chambers, Henry F

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is epidemic in the United States, even rivaling HIV/AIDS in its public health…”
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Is Panton‐Valentine Leukocidin the Major Virulence Determinant in Community‐Associated Methicillin‐Resistant Staphylococcus aureus Disease? by Voyich, Jovanka M. , Otto, Michael , Mathema, Barun , Braughton, Kevin R. , Whitney, Adeline R. , Welty, Diane , Long, R. Daniel , Dorward, David W. , Gardner, Donald J. , Lina, Gérard , Kreiswirth, Barry N. , DeLeo, Frank R. 

“…Methicillin‐resistant Staphylococcus aureus (MRSA) remains a major problem in hospitals, and it is now spreading in the community. A single toxin,…”
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Epidemic community-associated methicillin-resistant Staphylococcus aureus: Recent clonal expansion and diversification by Kennedy, Adam D, Otto, Michael, Braughton, Kevin R, Whitney, Adeline R, Chen, Liang, Mathema, Barun, Mediavilla, Jose R, Byrne, Kelly A, Parkins, Larye D, Tenover, Fred C, Kreiswirth, Barry N, Musser, James M, DeLeo, Frank R

“…Emerging and re-emerging infectious diseases, especially those caused by drug-resistant bacteria, are a major problem worldwide. Community-associated…”
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Molecular differentiation of historic phage-type 80/81 and contemporary epidemic Staphylococcus aureus by DeLeo, Frank R, Kennedy, Adam D, Chen, Liang, Wardenburg, Juliane Bubeck, Kobayashi, Scott D, Mathema, Barun, Braughton, Kevin R, Whitney, Adeline R, Villaruz, Amer E, Martens, Craig A, Porcella, Stephen F, McGavin, Martin J, Otto, Michael, Musser, James M, Kreiswirth, Barry N

“…Staphylococcus aureus is a bacterial pathogen known to cause infections in epidemic waves. One such epidemic was caused by a clone known as phage-type 80/81, a…”
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The SaeR/S Gene Regulatory System Is Essential for Innate Immune Evasion by Staphylococcus aureus by Voyich, Jovanka M., Vuong, Cuong, DeWald, Mark, Nygaard, Tyler K., Kocianova, Stanislava, Griffith, Shannon, Jones, Jennifer, Iverson, Courtney, Sturdevant, Daniel E., Braughton, Kevin R., Whitney, Adeline R., Otto, Michael, DeLeo, Frank R.

“…Methicillin-resistant Staphylococcus aureus is problematic both in hospitals and in the community. Currently, we have limited understanding of mechanisms of…”
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Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection by Malachowa, Natalia, Kobayashi, Scott D, Porter, Adeline R, Braughton, Kevin R, Scott, Dana P, Gardner, Donald J, Missiakas, Dominique M, Schneewind, Olaf, DeLeo, Frank R

“…Staphylococcus aureus produces numerous factors that facilitate survival in the human host. S. aureus coagulase (Coa) and von Willebrand factor-binding protein…”
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Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis by Diep, Binh An, Palazzolo-Ballance, Amy M, Tattevin, Pierre, Basuino, Li, Braughton, Kevin R, Whitney, Adeline R, Chen, Liang, Kreiswirth, Barry N, Otto, Michael, DeLeo, Frank R, Chambers, Henry F

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains typically carry genes encoding Panton-Valentine leukocidin (PVL). We used…”
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Sublytic concentrations of Staphylococcus aureus Panton-Valentine leukocidin alter human PMN gene expression and enhance bactericidal capacity by Graves, Shawna F., Kobayashi, Scott D., Braughton, Kevin R., Whitney, Adeline R., Sturdevant, Daniel E., Rasmussen, Devon L., Kirpotina, Liliya N., Quinn, Mark T., DeLeo, Frank R.

“…PVL‐mediated priming of PMNs enhances the host innate immune response. CA‐MRSA infections are often caused by strains encoding PVL, which can cause lysis of…”
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Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system by Vuong, Cuong, Voyich, Jovanka M., Fischer, Elizabeth R., Braughton, Kevin R., Whitney, Adeline R., DeLeo, Frank R., Otto, Michael

“…Summary The skin commensal and opportunistic pathogen Staphylococcus epidermidis is the leading cause of nosocomial and biofilm‐associated infections. Little…”
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Neutrophil Microbicides Induce a Pathogen Survival Response in Community-Associated Methicillin-Resistant Staphylococcus aureus by Palazzolo-Ballance, Amy M, Reniere, Michelle L, Braughton, Kevin R, Sturdevant, Daniel E, Otto, Michael, Kreiswirth, Barry N, Skaar, Eric P, DeLeo, Frank R

“…In recent years, there has been a dramatic increase in the incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections…”
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Bacterial Pathogens Modulate an Apoptosis Differentiation Program in Human Neutrophils by Kobayashi, Scott D., Braughton, Kevin R., Whitney, Adeline R., Voyich, Jovanka M., Schwan, Tom G., Musser, James M., DeLeo, Frank R.

“…Human polymorphonuclear leukocytes (PMNs or neutrophils) are essential to the innate immune response against bacterial pathogens. Recent evidence suggests that…”
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Complete Nucleotide Sequence Analysis of Plasmids in Strains of Staphylococcus aureus Clone USA300 Reveals a High Level of Identity among Isolates with Closely Related Core Genome Sequences by Kennedy, Adam D, Porcella, Stephen F, Martens, Craig, Whitney, Adeline R, Braughton, Kevin R, Chen, Liang, Craig, Carly T, Tenover, Fred C, Kreiswirth, Barry N, Musser, James M, DeLeo, Frank R

“…A community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strain known as pulsed-field type USA300 (USA300) is epidemic in the United…”
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Presence of Genes Encoding Panton-Valentine Leukocidin Is Not the Primary Determinant of Outcome in Patients with Hospital-Acquired Pneumonia Due to Staphylococcus aureus by SHARMA-KUINKEL, Batu K, AHN, Sun H, FOWLER, Vance G, RUDE, Thomas H, YURONG ZHANG, TONG, Steven Y. C, RUFFIN, Felicia, GENTER, Fredric C, BRAUGHTON, Kevin R, DELEO, Frank R, BARRIERE, Steven L

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Down-Regulation of Proinflammatory Capacity During Apoptosis in Human Polymorphonuclear Leukocytes by Kobayashi, Scott D, Voyich, Jovanka M, Braughton, Kevin R, DeLeo, Frank R

“…Polymorphonuclear leukocytes (PMNs) are essential to innate immunity in humans and contribute significantly to inflammation. Although progress has been made,…”
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Genome-Wide Protective Response Used by Group A Streptococcus to Evade Destruction by Human Polymorphonuclear Leukocytes by Voyich, Jovanka M., Sturdevant, Daniel E., Braughton, Kevin R., Kobayashi, Scott D., Lei, Benfang, Virtaneva, Kimmo, Dorward, David W., Musser, James M., DeLeo, Frank R.

“…Group A Streptococcus (GAS) evades polymorphonuclear leukocyte (PMN) phagocytosis and killing to cause human disease, including pharyngitis and necrotizing…”
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