Search Results - "Bratt, Debra"
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Effects of therapeutic vaccination on the control of SIV in rhesus macaques with variable responsiveness to antiretroviral drugs
Published in PloS one (17-06-2021)“…A therapeutic vaccine that induces lasting control of HIV infection could eliminate the need for lifelong adherence to antiretroviral therapy. This study…”
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Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates
Published in PloS one (21-12-2017)“…Recent avian and swine-origin influenza virus outbreaks illustrate the ongoing threat of influenza pandemics. We investigated immunogenicity and protective…”
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Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques
Published in Nature communications (22-08-2018)“…The immunological and virological events that contribute to the establishment of Zika virus (ZIKV) infection in humans are unclear. Here, we show that robust…”
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Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption
Published in The Journal of immunology (1950) (15-01-2017)“…During chronic lentiviral infection, poor clinical outcomes correlate both with systemic inflammation and poor proliferative ability of HIV-specific T cells;…”
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Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection
Published in Human vaccines & immunotherapeutics (03-07-2018)“…HIV-specific T-cell responses play a key role in controlling HIV infection, and therapeutic vaccines for HIV that aim to improve viral control will likely need…”
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Prospectively-collected, tooth-specific dosimetry correlated with adverse dental outcomes
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-08-2016)“…Objectives To correlate radiation dose to specific tooth-bearing portions of bone with adverse dental outcomes. Study Design Eighty-nine patients treated with…”
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Expression of LHX3 and SOX2 during mouse inner ear development
Published in Gene Expression Patterns (01-08-2007)“…A cascade of transcription factors is believed to regulate the coordinate differentiation of primordial inner ear cells into the subtypes of hair cells and…”
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Use of glnQ as a Counterselectable Marker for Creation of Allelic Exchange Mutations in Group B Streptococci
Published in Applied and Environmental Microbiology (01-01-2005)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Kinetics of myeloid derived suppressor cell frequency and function during SIV infection, combination antiretroviral therapy and treatment interruption1
Published in The Journal of immunology (1950) (14-12-2016)“…During chronic lentiviral infection, poor clinical outcomes correlate both with systemic inflammation and poor proliferative ability of HIV-specific T cells,…”
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10
Mucosal T Helper 17 and T Regulatory Cell Homeostasis Correlate with Acute Simian Immunodeficiency Virus Viremia and Responsiveness to Antiretroviral Therapy in Macaques
Published in AIDS research and human retroviruses (01-03-2019)“…Depletion of gut T helper 17 (Th17) cells during HIV infection leads to decreased mucosal integrity and increased disease progression. Conversely, T regulatory…”
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Use of glnQ as a counterselectable marker for creation of allelic exhange mutations in group B Streptococci
Published in Applied and environmental microbiology (01-01-2005)“…Efficient allelic exchange mutagenesis in group B streptococci (GBS) has been hampered by the lack of a counterselectable marker system. Growth inhibition of…”
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