Search Results - "Brass, E.P"

The novel phosphodiesterase inhibitor NM-702 improves claudication-limited exercise performance in patients with peripheral arterial disease by Brass, E.P, Anthony, R, Cobb, F.R

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Multiple skeletal muscle mitochondrial DNA deletions in patients with unilateral peripheral arterial disease by Brass, E.P., Wang, H., Hiatt, W.R.

“…Peripheral arterial disease (PAD) is associated with metabolic derangements and accumulation of the common 4977 bp mitochondrial DNA (mtDNA) deletion mutation…”
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Decreased activities of ubiquinol:ferricytochrome c oxidoreductase (complex III) and ferrocytochrome c:oxygen oxidoreductase (complex IV) in liver mitochondria from rats with hydroxycobalamin[c-lactam]-induced methylmalonic aciduria by Krahenbuhl, S., Chang, M., Brass, E.P., Hoppel, C.L.

“…Rats treated with hydroxycobalamin[c-lactam] (HCCL), a cobalamin analogue that induces methylmalonic aciduria, have increased hepatic mitochondrial content and…”
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Dietary substitution of medium-chain triglycerides improves insulin-mediated glucose metabolism in NIDDM subjects by Eckel, R.H. (University of Colorado Health Sciences Center, Denver, CO), Hanson, A.S, Chen, A.Y, Berman, J.N, Yost, T.J, Brass, E.P

“…Dietary medium-chain triglycerides (MCT) may improve insulin-mediated glucose metabolism. To examine this possibility, 10 non-insulin-dependent diabetes…”
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Hydroxycobalamin[c-lactam] increases total coenzyme A content in primary culture hepatocytes by accelerating coenzyme A biosynthesis secondary to Acyl-CoA accumulation by Brass, E P

“…Hydroxycobalamin[c-lactam] (HCCL) treatment in rats results in decreased hepatic L-methylmalonyl-CoA mutase activity and increased hepatic total CoA content…”
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Carnitine metabolism in the fasting rat by Brass, E.P., Hoppel, C.L.

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Hepatic cobalamin deficiency induced by hydroxycobalamin[c-lactam] treatment in rats is associated with decreased mitochondrial mRNA contents and accumulation of polycistronic mitochondrial RNAs by LEEDS, F. S, BRASS, E. P

“…Treatment of rats with hydroxycobalamin[c-lactam] (HCCL), a cobalamin antagonist, results in both increased hepatic mitochondrial content and the development…”
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Carnitine metabolism in the vitamin B-12-deficient rat by Brass, E.P, Stabler, S.P

“…In vitamin B-12 (cobalamin) deficiency the metabolism of propionyl-CoA and methylmalonyl-CoA are inhibited secondarily to decreased L-methylmalonyl-CoA mutase…”
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The role of carnitine and carnitine supplementation during exercise in man and in individuals with special needs by Brass, E.P. (Harbor-UCLA Medical Center, Torrance, CA.), Hiatt, W.R

“…Carnitine is critical for normal skeletal muscle bioenergetics. Carnitine has a dual role as it is required for long-chain fatty acid oxidation, and also…”
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Coenzyme A metabolism in vitamin B-12-deficient rats by Brass, E P, Tahiliani, A G, Allen, R H, Stabler, S P

“…Vitamin B-12 (cobalamin) deficiency results in decreased L-methylmalonyl-coenzyme A (CoA) mutase activity. The consequence of this defect on the cellular CoA…”
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Urinary organic acid excretion during feeding of medium-chain or long-chain triglyceride diets in patients with non-insulin-dependent diabetes mellitus by Brass, EP, Tserng, KY, Eckel, RH

“…Medium-chain triglycerides (MCTs) are absorbed and metabolized differently from long-chain triglycerides (LCTs). Recent data indicate that MCTs may be useful…”
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Facile method for preparation of 2,3-dinor-6-keto PGF1 alpha, the major urinary metabolite of prostacyclin by Balazy, M, Brass, E P, Gerber, J G, Nies, A S

“…We report a convenient and efficient method for the preparation of prostaglandin 2,3-dinor-6-keto-F1 alpha by incubating prostaglandin 6-keto-F1 alpha…”
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Disassociation between acidinsoluble acylcarnitines and ketogenesis following carnitine administration in vivo by Brass, E P, Hoppel, C L

“…1-Carnitine was administered to fed rats and the changes in plasma beta-hydroxybutrate concentration and liver acid-insoluble acylcarnitine content were…”
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Dietary substitution of medium chain triglycerides in subjects with non-insulin-dependent diabetes mellitus in an ambulatory setting: impact on glycemic control and insulin-mediated glucose metabolism by Yost, T J, Erskine, J M, Gregg, T S, Podlecki, D L, Brass, E P, Eckel, R H

“…We have previously shown in an acute inpatient setting that dietary substitution of 77.5% of fat kcal as medium chain triglycerides (MCT) increased…”
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