Search Results - "Brasil, Davi S.B"

In silico identification of novel allosteric inhibitors of Dengue virus NS2B/NS3 serine protease by da, Costa, da, Rocha, Pinheiro, Alan, da, Costa, da, Rocha, Josino, Luiz, da, Gonçalves, Lima, Anderson, Brasil, Davi

“…Although dengue is a disease that affects more than 100 countries and puts almost 400 million lives at risk each year, there is no approved antiviral in the…”
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Structure modeling of a metalloendopeptidase from Corynebacterium pseudotuberculosis by Guimarães, Luis C, Silva, Natália F, Miyoshi, Anderson, Schneider, Maria P.C, Silva, Artur, Azevedo, Vasco, Brasil, Davi S.B, Lameira, Jerônimo, Alves, Cláudio N

“…Abstract Metalloendopeptidases are zinc-dependent hydrolases enzymes with many different roles in biological systems, ranging from remodeling conjunctive…”
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Identification of (-)(E)-N-[2(S)-Hydroxy-2-(4-hydroxyphenyl) ethyl]ferulamide, a natural product isolated from Croton pullei: theoretical and experimental analysis by Silva, Silvana de O, Peixoto, Rosana N S, Silva, José Rogério A, Alves, Cláudio N, Guilhon, Giselle M S P, Santos, Lourivaldo S, Brasil, Davi do S B

“…Ferulic acid (FA) and its derivatives (FADs) are known for a variety of biological activities, such as photo-protective agent, antioxidant, antiatherogenic and…”
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Identification of Novel Protein Kinase Receptor Type 2 Inhibitors Using Pharmacophore and Structure-Based Virtual Screening by Cruz, Josiane V, Neto, Moysés F A, Silva, Luciane B, da S Ramos, Ryan, da S Costa, Josivan, Brasil, Davi S B, Lobato, Cleison C, da Costa, Glauber V, Bittencourt, José Adolfo H M, da Silva, Carlos H T P, Leite, Franco H A, Santos, Cleydson B R

“…The Protein Kinase Receptor type 2 (RIPK2) plays an important role in the pathogenesis of inflammatory diseases; it signals downstream of the NOD1 and NOD2…”
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Leishmanicidal Activity of (+)-Phyllanthidine and the Phytochemical Profile of Margaritaria nobilis (Phyllanthaceae) by Moraes, Lienne S, Donza, Marcio R H, Rodrigues, Ana Paula D, Silva, Bruno J M, Brasil, Davi S B, Zoghbi, Maria das Graças B, Andrade, Eloísa H A, Guilhon, Giselle M S P, Silva, Edilene O

“…The effects of the Securinega alkaloid (+)-phyllanthidine on Leishmania (L.) amazonensis and the first chemical investigation of Margaritaria nobilis L.f…”
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A SAR and QSAR study of new artemisinin compounds with antimalarial activity by Santos, Cleydson Breno R, Vieira, Josinete B, Lobato, Cleison C, Hage-Melim, Lorane I S, Souto, Raimundo N P, Lima, Clarissa S, Costa, Elizabeth V M, Brasil, Davi S B, Macêdo, Williams Jorge C, Carvalho, José Carlos T

“…The Hartree-Fock method and the 6-31G** basis set were employed to calculate the molecular properties of artemisinin and 20 derivatives with antimalarial…”
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Ligand- and structure-based virtual screening from 16-((diisobutylamino)methyl)-6α-hydroxyivouacapane-7β,17β-lactone a compound with potential anti-prostate cancer activity by Silva, Raí, Poiani, João, Ramos, Ryan, Costa, Josivan, Silva, Carlos, Brasil, Davi, Santos, Cleydson

“…Prostate cancer is one of the leading causes of disease and death on the planet. The probable bioactive pose of 16-((diisobutylamino)methyl)-…”
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Studies of NMR, molecular docking, and molecular dynamics simulation of new promising inhibitors of cruzaine from the parasite Trypanosoma cruzi by Costa, Renato A., Cruz, Jorddy N., Nascimento, Fabiana C. A., Silva, Sebastião G., Silva, Silvana O., Martelli, Marlice C., Carvalho, Samira M. L., Santos, Cleydson B. R., Neto, Antonio M. J. C., Brasil, Davi S. B.

“…Cruzaine is the major cysteine protease of Trypanosoma cruzi . Cruzaine is involved throughout the parasite’s life cycle in host cells, and is a promising…”
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A QSAR, pharmacokinetic and toxicological study of new artemisinin compounds with anticancer activity by Vieira, Josinete B, Braga, Francinaldo S, Lobato, Cleison C, Santos, César F, Costa, Josivan S, Bittencourt, José Adolfo H M, Brasil, Davi S B, Silva, Jocivânia O, Hage-Melim, Lorane I S, Macêdo, Williams Jorge C, Carvalho, José Carlos T, Santos, Cleydson Breno R

“…The Density Functional Theory (DFT) method and the 6-31G** basis set were employed to calculate the molecular properties of artemisinin and 20 derivatives with…”
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Isolation, Identification, predictions of biological activity and molecular docking of the diterpene jateorin obtained from the stem of odontocarya tamoides (D.C.) miers by da Costa, Renato Araujo, Silva, Jesiel C.F., Cruz, Jorddy N., Silva, Silvana O., Silva, Luciane B., Conceição, Gyselle S., Santos, Cleydson B.R., Ellena, Javier A., Arruda, Alberto C., Arruda, Mara S.P., Brasil, Davi S.B.

“…Phytochemical studies with the stem of Odontocarya tamoides (D.C.) Miers led to the isolation of the diterpene jateorin. In the structural elucidation of this…”
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Biotransformation of chalcones by the endophytic fungus Aspergillus flavus isolated from Paspalum maritimum trin by Corrêa, Marivaldo J. C, Nunes, Fátima M, Bitencourt, Heriberto R, Borges, Fábio C, Guilhon, Giselle M. S. P, Arruda, Mara S. P, Marinho, Andrey M. R, Santos, Alberdan S, Alves, Cláudio N, Brasil, Davi S. B, Santos, Lourivaldo S

“…The fungus Aspergillus flavus isolated as endophytic of the plant Paspalum maritimum Trin. was evaluated for its potential application in biotransformation…”
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A Computational Approach Applied to the Study of Potential Allosteric Inhibitors Protease NS2B/NS3 from Dengue Virus by Costa, Renato A. da, Rocha, João A. P. da, Pinheiro, Alan S., Costa, Andréia do S. S. da, Rocha, Elaine C. M. da, Silva, Rai. C., Gonçalves, Arlan da S., Santos, Cleydson B. R., Brasil, Davi do S. B.

“…Dengue virus (DENV) is a danger to more than 400 million people in the world, and there is no specific treatment. Thus, there is an urgent need to develop an…”
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Ricinine and other constituents of Aparisthmium cordatum (Euphorbiaceae) by Souza, Karla M.R., Guilhon, Giselle Maria Skelding Pinheiro, Santos, Lourivaldo Silva, Cascaes, Marcia M., Secco, Ricardo Souza, Brasil, Davi S.B., Andrade, Eloisa H.A., Marinho, Patricia S.B., Freire, Luciano R., Muller, Adolfo H.

“…The chemical study of Aparisthmium cordatum (Euphorbiaceae) led to the isolation of tannins, together with the alkaloid ricinine and other common compounds…”
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Synthesis, X-ray crystal structure and theoretical calculations of antileishmanial neolignan analogues by Nascimento, Josenaide P. do, Santos, Lourivaldo S., Santos, Regina Helena A., Tozzo, Érica, Ferreira, Janaina G., Carmo, Maria Carolina L. do, Brasil, Davi S. B., Alves, Cláudio N.

“…The synthesis and X-ray crystal diffraction structure of two analogues of neolignans, 2-(4-chlorophenyl)-1-phenylethanone (20) and…”
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Crystal structure and theoretical calculations of Julocrotine, a natural product with antileishmanial activity by Moreira, Rafael Y. O., Brasil, Davi S. B., Alves, Cláudio N., Guilhon, Giselle M. S. P., Santos, Lourivaldo S., Arruda, Mara S. P., Müller, Adolfo H., Barbosa, Patrícia S., Abreu, Alcicley S., Silva, Edilene O., Rumjanek, Victor M., Souza Jr, Jaime, da Silva, Albérico B. F., Santos, Regina H. de A.

“…Julocrotine, N‐(2,6‐dioxo‐1‐phenethyl‐piperidin‐3‐yl)‐2‐methyl‐butyramide, is a potent antiproliferative agent against the promastigote and amastigote forms of…”
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Volatiles, a glutarimide alkaloid and antimicrobial effects of Croton pullei (Euphorbiaceae) by Peixoto, Rosana N S, Guilhon, Giselle M S P, das Graças B Zoghbi, Maria, Araújo, Isabella S, Uetanabaro, Ana Paula T, Santos, Lourivaldo S, do S B Brasil, Davi

“…Chemical investigation of Croton pullei (Euphorbiaceae) collected in the Brazilian Amazon region was revisited. The chemical composition of the essential oils…”
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