Search Results - "Brash, James T"

Tamoxifen-Activated CreERT Impairs Retinal Angiogenesis Independently of Gene Deletion by Brash, James T., Bolton, Rebecca L., Rashbrook, Victoria S., Denti, Laura, Kubota, Yoshiaki, Ruhrberg, Christiana

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NRP1 function and targeting in neurovascular development and eye disease by Raimondi, Claudio, Brash, James T., Fantin, Alessandro, Ruhrberg, Christiana

“…Neuropilin 1 (NRP1) is expressed by neurons, blood vessels, immune cells and many other cell types in the mammalian body and binds a range of structurally and…”
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VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation by Fantin, Alessandro, Lampropoulou, Anastasia, Senatore, Valentina, Brash, James T, Prahst, Claudia, Lange, Clemens A, Liyanage, Sidath E, Raimondi, Claudio, Bainbridge, James W, Augustin, Hellmut G, Ruhrberg, Christiana

“…The vascular endothelial growth factor (VEGF) isoform VEGF165 stimulates vascular growth and hyperpermeability. Whereas blood vessel growth is essential to…”
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Characteristics and Outcomes for Recipients of NVX-CoV2373: A Real-World Retrospective Study in Germany by Kutikova, Lucie, Brash, James T, Helme, Kawitha, Brewster, Jack, Brand, Milou, Adam, Atif, Seager, Sarah, Kostev, Karel, Schelling, Jörg

“…Real-world evidence supports SARS-CoV-2 vaccination strategies during the COVID-19 pandemic. This real-world retrospective study utilized the German Disease…”
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Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay by Brash, James T, Ruhrberg, Christiana, Fantin, Alessandro

“…The primary function of the vascular endothelium in vertebrate organisms is to serve as a barrier between the blood and each tissue of the body, whereby the…”
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Risk of COVID-19 Diagnosis and Hospitalisation in Patients with Osteoarthritis or Back Pain Treated with Ibuprofen Compared to Other NSAIDs or Paracetamol: A Network Cohort Study by Xie, Junqing, Brash, James T., Turkmen, Cigdem, Driessen, Stefan, Varrassi, Giustino, Argyriou, George, Seager, Sarah, Reich, Christian, Prieto-Alhambra, Daniel

“…Objective We aimed to investigate whether ibuprofen use, compared with other non-selective non-steroidal anti-inflammatory drugs (ns-NSAIDs), cyclooxygenase-2…”
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Treatment of systemic lupus erythematosus: Analysis of treatment patterns in adult and paediatric patients across four European countries by Du, Mike, Dernie, Francesco, Català, Martí, Delmestri, Antonella, Man, Wai Yi, Brash, James T., van Ballegooijen, Hanne, Mercadé-Besora, Núria, Duarte-Salles, Talita, Mayer, Miguel-Angel, Leis, Angela, Ramírez-Anguita, Juan Manuel, Griffier, Romain, Verdy, Guillaume, Prats-Uribe, Albert, Pacurariu, Alexandra, Morales, Daniel R., De Lisa, Roberto, Galluzzo, Sara, Egger, Gunter F., Prieto-Alhambra, Daniel, Tan, Eng Hooi

“…•Characteristics and treatment patterns of 11,255 systemic lupus erythematosus patients analysed across four countries.•Glucocorticoids and hydroxychloroquine…”
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Standardised and Reproducible Phenotyping Using Distributed Analytics and Tools in the Data Analysis and Real World Interrogation Network (DARWIN EU) by Dernie, Francesco, Corby, George, Robinson, Abigail, Bezer, James, Mercade‐Besora, Nuria, Griffier, Romain, Verdy, Guillaume, Leis, Angela, Ramirez‐Anguita, Juan Manuel, Mayer, Miguel A., Brash, James T., Seager, Sarah, Parry, Rowan, Jodicke, Annika, Duarte‐Salles, Talita, Rijnbeek, Peter R., Verhamme, Katia, Pacurariu, Alexandra, Morales, Daniel, Pinheiro, Luis, Prieto‐Alhambra, Daniel, Prats‐Uribe, Albert

“…ABSTRACT Purpose The generation of representative disease phenotypes is important for ensuring the reliability of the findings of observational studies. The…”
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VEGF188 promotes corneal reinnervation after injury by Brash, James T, Denti, Laura, Ruhrberg, Christiana, Bucher, Franziska

“…Vascular endothelial growth factor A (VEGF) induces angiogenesis and vascular hyperpermeability in ocular tissues and is therefore a key therapeutic target for…”
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Risk of Arterial and Venous Thrombotic Events Among Patients with COVID-19: A Multi-National Collaboration of Regulatory Agencies from Canada, Europe, and United States by Lo Re Iii, Vincent, Cocoros, Noelle M, Hubbard, Rebecca A, Dutcher, Sarah K, Newcomb, Craig W, Connolly, John G, Perez-Vilar, Silvia, Carbonari, Dena M, Kempner, Maria E, Hernández-Muñoz, José J, Petrone, Andrew B, Pishko, Allyson M, Rogers Driscoll, Meighan E, Brash, James T, Burnett, Sean, Cohet, Catherine, Dahl, Matthew, DeFor, Terese A, Delmestri, Antonella, Djibo, Djeneba Audrey, Duarte-Salles, Talita, Harrington, Laura B, Kampman, Melissa, Kuntz, Jennifer L, Kurz, Xavier, Mercadé-Besora, Núria, Pawloski, Pamala A, Rijnbeek, Peter R, Seager, Sarah, Steiner, Claudia A, Verhamme, Katia, Wu, Fangyun, Zhou, Yunping, Burn, Edward, Paterson, J Michael, Prieto-Alhambra, Daniel

“…Few studies have examined how the absolute risk of thromboembolism with COVID-19 has evolved over time across different countries. Researchers from the…”
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Use of the HPRT gene to study nuclease-induced DNA double-strand break repair by Gravells, Polly, Ahrabi, Sara, Vangala, Rajani K, Tomita, Kazunori, Brash, James T, Brustle, Lena A, Chung, Christopher, Hong, Julia M, Kaloudi, Aikaterini, Humphrey, Timothy C, Porter, Andrew C G

“…Understanding the mechanisms of chromosomal double-strand break repair (DSBR) provides insight into genome instability, oncogenesis and genome engineering,…”
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Research Protocol for an Observational Health Data Analysis on the Adverse Events of Systemic Treatment in Patients with Metastatic Hormone-sensitive Prostate Cancer: Big Data Analytics Using the PIONEER Platform by Rajwa, Pawel, Borkowetz, Angelika, Abbott, Thomas, Alberti, Andrea, Bjartell, Anders, Brash, James T., Campi, Riccardo, Chilelli, Andrew, Conover, Mitchell, Constantinovici, Niculae, Davies, Eleanor, De Meulder, Bertrand, Eid, Sherrine, Gacci, Mauro, Golozar, Asieh, Hafeez, Haroon, Haque, Samiul, Hijazy, Ayman, Hulsen, Tim, Josefsson, Andreas, Khalid, Sara, Kolde, Raivo, Kotik, Daniel, Kurki, Samu, Lambrecht, Mark, Leung, Chi-Ho, Moreno, Julia, Nicoletti, Rossella, Nieboer, Daan, Oja, Marek, Palanisamy, Soundarya, Prinsen, Peter, Reich, Christian, Raffaele Resta, Giulio, Ribal, Maria J., Gómez Rivas, Juan, Smith, Emma, Snijder, Robert, Steinbeisser, Carl, Vandenberghe, Frederik, Cornford, Philip, Evans-Axelsson, Susan, N'Dow, James, Willemse, Peter-Paul M.

“…Despite their efficacy, novel combination systemic therapies for metastatic hormone-sensitive prostate cancer (mHSPC) are associated with side effects. Our…”
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Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay by Brash, James T., Ruhrberg, Christiana, Fantin, Alessandro

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