Search Results - "Brash, A."

Phonon-assisted population inversion of a single InGaAs/GaAs quantum dot by pulsed laser excitation by Quilter, J H, Brash, A J, Liu, F, Glässl, M, Barth, A M, Axt, V M, Ramsay, A J, Skolnick, M S, Fox, A M

“…We demonstrate a new method to realize the population inversion of a single InGaAs/GaAs quantum dot excited by a laser pulse tuned within the neutral exciton…”
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Arachidonic acid as a bioactive molecule by Brash, A R

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Nanocavity enhanced photon coherence of solid-state quantum emitters operating up to 30 K by Brash, A J, Iles-Smith, J

“…Solid-state emitters such as epitaxial quantum dots have emerged as a leading platform for efficient, on-demand sources of indistinguishable photons, a key…”
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Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle by Feinberg, Hadar, Jégouzo, Sabine A.F., Rowntree, Thomas J.W., Guan, Yue, Brash, Matthew A., Taylor, Maureen E., Weis, William I., Drickamer, Kurt

“…Mincle facilitates establishment of persistent infections of macrophages by Mycobacterium tuberculosis. Results: The mechanism of mincle binding to…”
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High-fidelity initialization of long-lived quantum dot hole spin qubits by reduced fine-structure splitting by Brash, A. J., Martins, L. M. P. P., Liu, F., Quilter, J. H., Ramsay, A. J., Skolnick, M. S., Fox, A. M.

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Autoxidation of methyl linoleate: Identification of the bis‐allylic 11‐hydroperoxide by Brash, Alan R.

“…Based on the understanding of lipid peroxidation as a free radical chain reaction, over 50 yr ago the three primary products of linoleic acid autoxidation were…”
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Two distinct pathways of formation of 4-hydroxynonenal. Mechanisms of nonenzymatic transformation of the 9- and 13-hydroperoxides of linoleic acid to 4-hydroxyalkenals by Schneider, C, Tallman, K A, Porter, N A, Brash, A R

“…The mechanism of formation of 4-hydroxy-2E-nonenal (4-HNE) has been a matter of debate since it was discovered as a major cytotoxic product of lipid…”
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A comprehensive model of positional and stereo control in lipoxygenases by Coffa, Gianguido, Schneider, Claus, Brash, Alan R.

“…The lipoxygenase gene family can synthesize an array of chiral hydroperoxy derivatives from polyunsaturated fatty acids. An individual enzyme, however, reacts…”
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Molecular Cloning of an Allene Oxide Synthase: A Cytochrome P450 Specialized for the Metabolism of Fatty Acid Hydroperoxides by Song, Wen-Chao, Funk, Colin D., Brash, Alan R.

“…Allene oxide synthases convert lipoxygenase-derived fatty acid hydroperoxides to unstable allene epoxides. In plants, an allene oxide is a precursor of the…”
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Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate by Brash, Alan R.

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Autoxidative Transformation of Chiral omega 6 Hydroxy Linoleic and Arachidonic Acids to Chiral 4-Hydroxy-2E-nonenal by Schneider, C, Porter, NA, Brash, A R

“…Recently, we established that 13S-hydroperoxy-linoleic acid is converted to 4S-hydroperoxy-nonenal (4S-HPNE) during autoxidation, implicating hydrogen…”
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The Lipoxygenase Gene ALOXE3 Implicated in Skin Differentiation Encodes a Hydroperoxide Isomerase by Yu, Zheyong, Schneider, Claus, Boeglin, William E., Marnett, Lawrence J., Brash, Alan R.

“…Lipoxygenase (LOX) enzymes form fatty acid hydroperoxides used in membrane remodeling and cell signaling. Mammalian epidermal LOX type 3 (eLOX3) is distinctive…”
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Identification of a Naturally Occurring Peroxidase-Lipoxygenase Fusion Protein by Koljak, Reet, Boutaud, Olivier, Shieh, Bih-Hwa, Samel, Nigulas, Brash, Alan R.

“…A distant relative of catalase that is specialized for metabolism of a fatty acid hydroperoxide was identified. This heme peroxidase occurs in coral as part of…”
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Alterations in Lipoxygenase and Cyclooxygenase-2 Catalytic Activity and mRNA Expression in Prostate Carcinoma by Shappell, Scott B., Manning, Suzanne, Boeglin, William E., Guan, You-Fei, Roberts, Richard L., Davis, Linda, Olson, Sandra J., Jack, Gregory S., Coffey, Christopher S., Wheeler, Thomas M., Breyer, Matthew D., Brash, Alan R.

“…Recent studies in prostate tissues and especially cell lines have suggested roles for arachidonic acid (AA) metabolizing enzymes in prostate adenocarcinoma…”
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Oxygenation of biological membranes by the pure reticulocyte lipoxygenase by Kuhn, H, Belkner, J, Wiesner, R, Brash, A R

“…We find that the reticulocyte lipoxygenase can oxygenate rat liver mitochondrial membranes, beef heart submitochondrial particles, rat liver endoplasmic…”
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Purification of an Allene Oxide Synthase and Identification of the Enzyme as a Cytochrome P-450 by Song, Wen-Chao, Brash, Alan R.

“…Fatty acid hydroperoxides (lipoxygenase products) are metabolized to allene oxides by a type of dehydrase that has been detected in plants, corals, and…”
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Discovery of a Second 15S-Lipoxygenase in Humans by Brash, Alan R., Boeglin, William E., Chang, Min S.

“…The lipoxygenase metabolism of arachidonic acid occurs in specific blood cell types and epithelial tissues and is activated in inflammation and tissue injury…”
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15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor γ and inhibits proliferation in PC3 prostate carcinoma cells by SHAPPELL, Scott B, GUPTA, Rajnish A, MATUSIK, Robert J, BRASH, Alan R, DUBOIS, Raymond N, MANNING, Suzanne, WHITEHEAD, Robert, BOEGLIN, William E, SCHNEIDER, Claus, CASE, Tom, PRICE, James, JACK, Gregory S, WHEELER, Thomas M

“…15-Lipoxygenase (15-LOX)-2 is expressed in benign prostate secretory cells and benign prostate produces 15S-hydroxyeicosatetraenoic acid (15S-HETE) from…”
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On the evolutionary origin of cyclooxygenase (COX) isozymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages by Järving, Reet, Järving, Ivar, Kurg, Reet, Brash, Alan R, Samel, Nigulas

“…In vertebrates, COX-1 and COX-2, two cyclooxygenase isozymes with different physiological functions and gene regulation, catalyze identical reactions in…”
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Expression of a flax allene oxide synthase cDNA leads to increased endogenous jasmonic acid (JA) levels in transgenic potato plants but not to a corresponding activation of JA-responding genes by Harms, K. (Institut fur Genbiologische Forschung, Berlin, Germany.), Atzorn, R, Brash, A, Kuhn, H, Wasternack, C, Willmitzer, L, Pena-Cortes, H

“…Both jasmonic acid (JA) and its methyl ester, methyl jasmonate (MeJA), are thought to be significant components of the signaling pathway regulating the…”
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