Search Results - "Brann, David H."

COVID-19 and the Chemical Senses: Supporting Players Take Center Stage by Cooper, Keiland W., Brann, David H., Farruggia, Michael C., Bhutani, Surabhi, Pellegrino, Robert, Tsukahara, Tatsuya, Weinreb, Caleb, Joseph, Paule V., Larson, Eric D., Parma, Valentina, Albers, Mark W., Barlow, Linda A., Datta, Sandeep Robert, Di Pizio, Antonella

“…The main neurological manifestation of COVID-19 is loss of smell or taste. The high incidence of smell loss without significant rhinorrhea or nasal congestion…”
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Finding the Brain in the Nose by Brann, David H, Datta, Sandeep Robert

“…Olfaction is fundamentally distinct from other sensory modalities. Natural odor stimuli are complex mixtures of volatile chemicals that interact in the nose…”
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A circuit from hippocampal CA2 to lateral septum disinhibits social aggression by Leroy, Felix, Park, Jung, Asok, Arun, Brann, David H., Meira, Torcato, Boyle, Lara M., Buss, Eric W., Kandel, Eric R., Siegelbaum, Steven A.

“…Although the hippocampus is known to be important for declarative memory, it is less clear how hippocampal output regulates motivated behaviours, such as…”
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A transcriptional rheostat couples past activity to future sensory responses by Tsukahara, Tatsuya, Brann, David H., Pashkovski, Stan L., Guitchounts, Grigori, Bozza, Thomas, Datta, Sandeep Robert

“…Animals traversing different environments encounter both stable background stimuli and novel cues, which are thought to be detected by primary sensory neurons…”
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Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia by Brann, David H, Tsukahara, Tatsuya, Weinreb, Caleb, Lipovsek, Marcela, Van den Berge, Koen, Gong, Boying, Chance, Rebecca, Macaulay, Iain C, Chou, Hsin-Jung, Fletcher, Russell B, Das, Diya, Street, Kelly, de Bezieux, Hector Roux, Choi, Yoon-Gi, Risso, Davide, Dudoit, Sandrine, Purdom, Elizabeth, Mill, Jonathan, Hachem, Ralph Abi, Matsunami, Hiroaki, Logan, Darren W, Goldstein, Bradley J, Grubb, Matthew S, Ngai, John, Datta, Sandeep Robert

“…Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A key question is whether SARS-CoV-2 (CoV-2) - the causal agent in…”
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Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory by Leroy, Felix, Brann, David H., Meira, Torcato, Siegelbaum, Steven A.

“…Input-timing-dependent plasticity (ITDP) is a circuit-based synaptic learning rule by which paired activation of entorhinal cortical (EC) and Schaffer…”
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Discovering Precise Temporal Patterns in Large-Scale Neural Recordings through Robust and Interpretable Time Warping by Williams, Alex H., Poole, Ben, Maheswaranathan, Niru, Dhawale, Ashesh K., Fisher, Tucker, Wilson, Christopher D., Brann, David H., Trautmann, Eric M., Ryu, Stephen, Shusterman, Roman, Rinberg, Dmitry, Ölveczky, Bence P., Shenoy, Krishna V., Ganguli, Surya

“…Though the temporal precision of neural computation has been studied intensively, a data-driven determination of this precision remains a fundamental…”
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Medial and Lateral Entorhinal Cortex Differentially Excite Deep versus Superficial CA1 Pyramidal Neurons by Masurkar, Arjun V., Srinivas, Kalyan V., Brann, David H., Warren, Richard, Lowes, Daniel C., Siegelbaum, Steven A.

“…Although hippocampal CA1 pyramidal neurons (PNs) were thought to comprise a uniform population, recent evidence supports two distinct sublayers along the…”
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Mechanisms of SARS-CoV-2-associated anosmia by Tsukahara, Tatsuya, Brann, David H, Datta, Sandeep Robert

“…Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory…”
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Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium by Finlay, John B, Brann, David H, Abi Hachem, Ralph, Jang, David W, Oliva, Allison D, Ko, Tiffany, Gupta, Rupali, Wellford, Sebastian A, Moseman, E Ashley, Jang, Sophie S, Yan, Carol H, Matsunami, Hiroaki, Tsukahara, Tatsuya, Datta, Sandeep Robert, Goldstein, Bradley J

“…SARS-CoV-2 causes profound changes in the sense of smell, including total smell loss. Although these alterations are often transient, many patients with…”
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Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory by Leroy, Felix, Brann, David H., Meira, Torcato, Siegelbaum, Steven A.

“…(Neuron 95, 1089–1102.e1–e5; August 30, 2017)Main Text In the original publication of this paper, we reported that paired activation of the direct cortical and…”
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Regulation by Presynaptic NMDA Receptors of Non-Linear Postsynaptic Summation of the Cortical Input to CA1 Pyramidal Neurons by Buss, Eric W., Jiang, Yu-Qiu, Santoro, Bina, Brann, David H., Nicholson, Daniel A., Siegelbaum, Steven A., Sun, Qian

“…•Perforant path (PP) burst evokes supralinear EPSP summation in CA1, but not CA2.•Strong supralinear temporal summation of EPSP in CA1 requires NMDAR…”
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Frequency-Dependent Synaptic Dynamics Differentially Tune CA1 and CA2 Pyramidal Neuron Responses to Cortical Input by Sun, Qian, Buss, Eric W, Jiang, Yu-Qiu, Santoro, Bina, Brann, David H, Nicholson, Daniel A, Siegelbaum, Steven A

“…Entorhinal cortex neurons make monosynaptic connections onto distal apical dendrites of CA1 and CA2 pyramidal neurons through the perforant path (PP)…”
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Postsynaptic integrative properties of dorsal CA1 pyramidal neuron subpopulations by Masurkar, Arjun V, Tian, Chengju, Warren, Richard, Reyes, Isabel, Lowes, Daniel C, Brann, David H, Siegelbaum, Steven A

“…The population activity of CA1 pyramidal neurons (PNs) segregates along anatomical axes with different behaviors, suggesting that CA1 PNs are functionally…”
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Discovering Precise Temporal Patterns in Large-Scale Neural Recordings through Robust and Interpretable Time Warping by Williams, Alex H., Poole, Ben, Maheswaranathan, Niru, Dhawale, Ashesh K., Fisher, Tucker, Wilson, Christopher D., Brann, David H., Trautmann, Eric M., Ryu, Stephen, Shusterman, Roman, Rinberg, Dmitry, Ölveczky, Bence P., Shenoy, Krishna V., Gangul, Surya

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Pseudotumor Cerebri Syndrome With COVID-19: A Case Series by Mukharesh, Loulwah, Bouffard, Marc A., Fortin, Elizabeth, Brann, David H., Datta, Sandeep Robert, Prasad, Sashank, Chwalisz, Bart K.

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Heterogeneity in Kv2 Channel Expression Shapes Action Potential Characteristics and Firing Patterns in CA1 versus CA2 Hippocampal Pyramidal Neurons by Palacio, Stephanie, Chevaleyre, Vivien, Brann, David H, Murray, Karl D, Piskorowski, Rebecca A, Trimmer, James S

“…The CA1 region of the hippocampus plays a critical role in spatial and contextual memory, and has well-established circuitry, function and plasticity. In…”
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Discovering Precise Temporal Patterns in Large-Scale Neural Recordings through Robust and Interpretable Time Warping by Williams, Alex H., Poole, Ben, Maheswaranathan, Niru, Dhawale, Ashesh K., Fisher, Tucker, Wilson, Christopher D., Brann, David H., Trautmann, Eric M., Ryu, Stephen, Shusterman, Roman, Rinberg, Dmitry, Ölveczky, Bence P., Shenoy, Krishna V., Ganguli, Surya

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A hippocampal CA2 to lateral septal circuit disinhibits social aggression by Leroy, Felix, Park, Jung, Asok, Arun, Brann, David H., Meira, Torcato, Boyle, Lara, Buss, Eric W., Kandel, Eric R., Siegelbaum, Steven A.

“…Although the hippocampus is known to be important for declarative memory, how hippocampal output regulates motivated behaviors, such as social aggression, is…”
Get full text