Search Results - "Branco de Barros, André Luís"

Gold-Loaded Polymeric Micelles for Computed Tomography-Guided Radiation Therapy Treatment and Radiosensitization by Al Zaki, Ajlan, Joh, Daniel, Cheng, Zhiliang, De Barros, André Luís Branco, Kao, Gary, Dorsey, Jay, Tsourkas, Andrew

“…Gold nanoparticles (AuNPs) have generated interest as both imaging and therapeutic agents. AuNPs are attractive for imaging applications since they are…”
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Nuclear factor kappa B expression in non-small cell lung cancer by Zhang, Leilei, Ludden, Claudia M., Cullen, Alexander J., Tew, Kenneth D., Branco de Barros, André Luís, Townsend, Danyelle M.

“…In this mini-review, we discuss the role of NF-κB, a proinflammatory transcription factor, in the expression of genes involved in inflammation, proliferation,…”
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pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment by Nunes, Shirleide Santos, Miranda, Sued Eustaquio Mendes, de Oliveira Silva, Juliana, Fernandes, Renata Salgado, de Alcântara Lemos, Janaína, de Aguiar Ferreira, Carolina, Townsend, Danyelle M., Cassali, Geovanni Dantas, Oliveira, Mônica Cristina, Branco de Barros, André Luís

“…Irinotecan (IRN) is a semisynthetic derivative of camptothecin that acts as a topoisomerase I inhibitor. IRN is used worldwide for the treatment of several…”
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Recent advances and limitations in the application of kahalalides for the control of cancer by Wyer, Scott, Townsend, Danyelle M., Ye, Zhiwei, Kourtidis, Antonis, Choo, Yeun-Mun, de Barros, André Luís Branco, Donia, Mohamed S., Hamann, Mark T.

“…Since the discovery of the kahalalide family of marine depsipeptides in 1993, considerable work has been done to develop these compounds as new and…”
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Thermosensitive Nanosystems Associated with Hyperthermia for Cancer Treatment by Pereira Gomes, Isabela, Aparecida Duarte, Jaqueline, Chaves Maia, Ana Luiza, Rubello, Domenico, Townsend, Danyelle M, Branco de Barros, André Luís, Leite, Elaine Amaral

“…Conventional chemotherapy regimens have limitations due to serious adverse effects. Targeted drug delivery systems to reduce systemic toxicity are a powerful…”
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Aptamers directly radiolabeled with technetium-99m as a potential agent capable of identifying carcinoembryonic antigen (CEA) in tumor cells T84 by Correa, Cristiane Rodrigues, de Barros, André Luís Branco, Ferreira, Carolina de Aguiar, de Goes, Alfredo Miranda, Cardoso, Valbert Nascimento, de Andrade, Antero Silva Ribeiro

“…Aptamers are small oligonucleotides that are selected to bind with high affinity and specificity to a target molecule. Aptamers are emerging as a new class of…”
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Mesoporous silica SBA-16/hydroxyapatite-based composite for ciprofloxacin delivery to bacterial bone infection by Andrade, Gracielle Ferreira, Faria, Jerusa Araújo Quintão Arantes, Gomes, Dawidson Assis, de Barros, André Luís Branco, Fernandes, Renata Salgado, Coelho, Amanda Cristina Soares, Takahashi, Jacqueline Aparecida, da Silva Cunha, Armando, de Sousa, Edésia Martins Barros

“…The development of systems that can prevent infections and also ensure bone integration as well as regeneration have been of great interest for pharmaceutical…”
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Synthesis and antimicrobial evaluation of two peptide LyeTx I derivatives modified with the chelating agent HYNIC for radiolabeling with technetium-99m by Fuscaldi, Leonardo Lima, Dos Santos, Daniel Moreira, Pinheiro, Natália Gabriela Silva, Araújo, Raquel Silva, de Barros, André Luís Branco, Resende, Jarbas Magalhães, Fernandes, Simone Odília Antunes, de Lima, Maria Elena, Cardoso, Valbert Nascimento

“…Current diagnostic methods and imaging techniques are not able to differentiate septic and aseptic inflammation. Thus, reliable methods are sought to provide…”
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Radiolabeling of cidofovir with technetium-99m and biodistribution studies by Arribada, Raquel Gregorio, Pereira, Nara Caroline, Cardoso, Valbert Nascimento, Cunha Júnior, Armando da Silva, Barros, André Luís Branco de

“…Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that enables real-time monitoring of the drug. Essays were performed in…”
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Co-delivery of doxorubicin, docosahexaenoic acid, and α-tocopherol succinate by nanostructured lipid carriers has a synergistic effect to enhance antitumor activity and reduce toxicity by Lages, Eduardo Burgarelli, Fernandes, Renata Salgado, Silva, Juliana de Oliveira, de Souza, Ângelo Malachias, Cassali, Geovanni Dantas, de Barros, André Luís Branco, Miranda Ferreira, Lucas Antônio

“…[Display omitted] •Design of a novel nanostructured lipid carriers (NLC) formulation loading DOX, DHA, and TS.•Hydrophobic ion-pairing with TS allows high DOX…”
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Will curcumin nanosystems be the next promising antiviral alternatives in COVID-19 treatment trials? by Dourado, Douglas, Freire, Danielle T., Pereira, Daniel T., Amaral-Machado, Lucas, N. Alencar, Éverton, de Barros, André Luís Branco, Egito, E. Sócrates T.

“…The COVID-19 has become of striking interest since the number of deaths is constantly rising all over the globe, and the search for an efficient treatment is…”
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Folate-coated, long-circulating and pH-sensitive liposomes enhance doxorubicin antitumor effect in a breast cancer animal model by de Oliveira Silva, Juliana, Fernandes, Renata Salgado, Ramos Oda, Caroline Mari, Ferreira, Tiago Hilário, Machado Botelho, Ana Flávia, Martins Melo, Marília, de Miranda, Marcelo Coutinho, Assis Gomes, Dawidson, Dantas Cassali, Geovanni, Townsend, Danyelle M., Rubello, Domenico, Oliveira, Mônica Cristina, de Barros, André Luís Branco

“…Long circulating pH-sensitive liposomes have been shown to effectively deliver doxorubicin (DOX) to tumors and reduce its toxic effects. Folic acid receptors…”
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Long-circulating, pH-sensitive liposomes versus long-circulating, non-pH-sensitive liposomes as a delivery system for tumor identification by de Barros, André Luís Branco, Mota, Luciene das Graças, Soares, Daniel Crístian Ferreira, de Souza, Cristina Maria, Cassali, Geovanni Dantas, Oliveira, Mônica Cristina, Cardoso, Valbert Nascimento

“…Bombesin (BBN) is a tetradecapeptide that binds specifically to gastrin-releasing peptide receptors in humans. Several forms of cancer, including lung,…”
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Investigation of the antitumor activity and toxicity of long-circulating and fusogenic liposomes co-encapsulating paclitaxel and doxorubicin in a murine breast cancer animal model by Franco, Marina Santiago, Roque, Marjorie Coimbra, de Barros, André Luís Branco, de Oliveira Silva, Juliana, Cassali, Geovanni Dantas, Oliveira, Mônica Cristina

“…[Display omitted] •Treatment of murine breast cancer with LCFL-PTX/DXR is superior to treatments with free PTX or free DXR.•No heart damage is observed when…”
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Tumor bombesin analog loaded long-circulating and pH-sensitive liposomes as tool for tumor identification by de Barros, André Luís Branco, Mota, Luciene das Graças, Soares, Daniel Crístian Ferreira, Coelho, Marina Melo Antunes, Oliveira, Mônica Cristina, Cardoso, Valbert Nascimento

“…Long-circulating and pH-sensitive liposomes trapping 99mTc-HYNIC-βAla-bombesin (7–14) (aSpHL- 99mTc-BBN (7–14)) were successfully prepared. Biodistribution…”
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Radiolabeled bombesin derivatives for preclinical oncological imaging by Ferreira, Carolina de Aguiar, Fuscaldi, Leonardo Lima, Townsend, Danyelle M, Rubello, Domenico, Barros, André Luís Branco de

“…Abstract Despite efforts, cancer is still one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2…”
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Bombesin derivative radiolabeled with technetium-99m as agent for tumor identification by de Barros, André Luís Branco, Mota, Luciene das Graças, Ferreira, Carolina de Aguiar, Oliveira, Mônica Cristina de, Góes, Alfredo Miranda de, Cardoso, Valbert Nascimento

“…Preparation of technetium-labeled bombesin derivative for tumor identification. A bombesin derivative was successfully radiolabeled in high labeling yield…”
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Evaluation of acute toxicity and in vitro antitumor activity of a novel doxorubicin-loaded folate-coated pH-sensitive liposome by de Oliveira Silva, Juliana, Fernandes, Renata Salgado, de Alcântara Lemos, Janaína, Cassali, Geovanni Dantas, de Paula Sabino, Adriano, Townsend, Danyelle M., Oliveira, Mônica Cristina, de Barros, André Luís Branco

“…Doxorubicin (DOX) loaded liposomes have been used and studied in the last decades due to the significant decrease in DOX induced cardiac and systemic toxicity…”
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A novel d-glucose derivative radiolabeled with technetium-99m: Synthesis, biodistribution studies and scintigraphic images in an experimental model of Ehrlich tumor by de Barros, André Luís Branco, Cardoso, Valbert Nascimento, Mota, Luciene das Graças, Leite, Elaine Amaral, de Oliveira, Mônica Cristina, Alves, Ricardo José

“…A d-glucose analogue was synthesized; its biodistribution studies and scintigraphic imagens were performed. A d-glucose-MAG 3 derivative was successfully…”
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Preclinical toxicological study of long-circulating and fusogenic liposomes co-encapsulating paclitaxel and doxorubicin in synergic ratio by Roque, Marjorie Coimbra, da Silva, Caroline Dohanik, Lempek, Marthin Raboch, Cassali, Geovanni Dantas, de Barros, André Luís Branco, Melo, Marília Martins, Oliveira, Mônica Cristina

“…Combination therapy between paclitaxel (PTX) and doxorubicin (DXR) is applied as the first-line treatment of breast cancer. Co-administration of drugs at…”
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