Search Results - "Branch, Todd M"
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The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold
Published in Bioorganic & medicinal chemistry letters (06-08-2001)“…A series of carboxylic acids was prepared based on cyclohexylglycine scaffolds and tested for potency as matrix metalloproteinase (MMP) inhibitors. Detailed…”
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Fully Automated 96-Well Liquid−Liquid Extraction for Analysis of Biological Samples by Liquid Chromatography with Tandem Mass Spectrometry
Published in Analytical chemistry (Washington) (01-02-2001)“…A fully automated high-throughput liquid−liquid extraction (LLE) methodology has been developed for preparation of biological samples using a 96-well LLE plate…”
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Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines
Published in Journal of medicinal chemistry (29-03-2001)“…A series of carboxylic acids were prepared from a propargylglycine scaffold and tested for efficacy as matrix metalloproteinase (MMP) inhibitors. Detailed SAR…”
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Potent and Selective Carboxylic Acid-Based Inhibitors of Matrix Metalloproteinases
Published in Journal of medicinal chemistry (02-08-2001)“…A novel series of carboxylic acids containing a substituted piperidine were synthesized and tested for inhibition of selected matrix metalloproteinases…”
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Hydrogen Bond Energies of Hydrogen Chloride−Carbonyl Complexes
Published in Journal of physical chemistry (1952) (08-02-1996)“…Gas phase hydrogen bonding was studied via infrared spectroscopy in the following systems: methyl acetate−hydrogen chloride, methyl formate−hydrogen chloride,…”
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Time- and Wavelength-Resolved Fluorescence Detection for Capillary Zone Electrophoresis with Axial Excitation
Published in Microchemical journal (01-10-1997)“…Capillary zone electrophoresis (CZE) has become a powerful tool in separation science. Detection methods for this technique, however, have not yet matured. We…”
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