Search Results - "Brañes, Jorge"
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Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer
Published in PloS one (04-05-2017)“…Teneurins are a family of highly conserved pair-rule proteins involved in morphogenesis and development of the central nervous system. Their function in adult…”
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2
Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women
Published in Oncotarget (28-08-2015)“…The evidence linking obesity with ovarian cancer remains controversial. Leptin is expressed at higher levels in obese women and stimulates cell migration in…”
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3
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells
Published in BMC cancer (15-04-2015)“…An increase in circulating platelets, or thrombocytosis, is recognized as an independent risk factor of bad prognosis and metastasis in patients with ovarian…”
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The Relationship Between Neuraxial Anesthesia and Advanced Ovarian Cancer-Related Outcomes in the Chilean Population
Published in Anesthesia and analgesia (01-09-2013)“…BACKGROUND:Mixed evidence has been published relating the use of regional anesthesia during oncologic surgery to a decrease in time to cancer recurrence and…”
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Body Composition and Metabolic Dysfunction Really Matter for the Achievement of Better Outcomes in High-Grade Serous Ovarian Cancer
Published in Cancers (10-02-2023)“…Although obesity-associated metabolic disorders have a negative impact on various cancers, such evidence remains controversial for ovarian cancer. Here, we…”
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Screening trial of human papillomavirus for early detection of cervical cancer in Santiago, Chile
Published in International journal of cancer (15-02-2013)“…Cervical cancer mortality in Chile is four times higher than in developed countries. We compared the accuracy of human papillomavirus (HPV) DNA testing and…”
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Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-12-2013)“…The use of the type 2 diabetics drug metformin has been correlated with enhanced progression-free survival in ovarian cancer. The literature has speculated…”
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Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression
Published in Oncotarget (28-03-2017)“…Clinical studies have suggested a survival benefit in ovarian cancer patients with type 2 diabetes mellitus taking metformin, however the mechanism by which…”
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9
The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium
Published in Endocrine-related cancer (01-06-2007)“…Cancers of the reproductive tract account for 12% of all malignancies in women. As previous studies have shown that oestrogen metabolites can cause apoptosis,…”
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10
Human papillomavirus testing in cervical cancer screening at a public health service of Santiago, Chile
Published in Revista medíca de Chile (01-01-2015)“…Molecular techniques for human papillomavirus (HPV) detection have a good performance as screening tests and could be included in cervical cancer early…”
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2-methoxyestradiol mediates apoptosis through caspase-dependent and independent mechanisms in ovarian cancer cells but not in normal counterparts
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-11-2008)“…The estrogen metabolite 2-methoxyestradiol has shown antitumorigenic action in some epithelial tumors. In the present work we investigate its effects in…”
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In vitro cell response to chemotherapeutic agents, to personalize ovarian cancer treatment: report of two cases
Published in Revista medíca de Chile (01-05-2013)“…Our laboratory has implemented an in vitro assay to estimate the response to chemotherapy in ovarian cancer cells pertaining to individual patients. In two…”
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13
Pelvic intravenous leiomyomatosis with intracardiac extension: report of two cases
Published in Revista medíca de Chile (01-07-2012)“…Symptoms predominate. Diagnosis is based on clinical findings and appropriate imaging. We report two females, aged 35 and 51 years. One of them presented with…”
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14
Teneurin protein family: An emerging role in human tumorigenesis and drug resistance
Published in Cancer letters (29-12-2012)“…Highlights ► We performed an in-depth literature and data search on reported expression of teneurins in human tumors. ► Aberrant expression of teneurin-2 and…”
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Abstract 922: Body composition and metabolic dysfunction really matter for the achievement of better outcomes in high-grade serous ovarian cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Our objective was to evaluate the impact of body composition (BC), beyond body mass index (BMI), and lipid metabolism disorders on therapeutic responses and…”
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Impact of obesity on survival and recurrence of high grade serous carcinoma of the ovary
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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17
ABORDAJE LAPAROSCÓPICO EN CÁNCER DE ENDOMETRIO
Published in Revista chilena de obstetricia y ginecología (2009)“…El cáncer de endometrio es una neoplasia ginecológica relevante en todo el mundo, con cambios acelerados en su manejo. La cirugía es el tratamiento de…”
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Abstract 4314: Prediction of chemotherapy response and metabolism for the tailoring of ovarian cancer treatment
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Ovarian cancer patients respond well to first line chemotherapy but present high incidences of toxicity followed by consistent relapse within 18 months…”
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Abstract 3730: 2-Methoxyestradiol induces differentiation of epithelial ovarian cancer-initiating cells sensitizing them to chemotherapy
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Ovarian cancer is the most deadly gynecological malignancy. Its lethality is mainly due to late diagnosis and acquisition of resistance to available therapies…”
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TUMOR DE LOS CORDONES SEXUALES CON TÚBULOS ANULARES DEL OVARIO NO ASOCIADO A SÍNDROME DE PEUTZ-JEGHERS: REPORTE DE UN CASO
Published in Revista chilena de obstetricia y ginecología (2006)“…Se presenta el raro caso de una mujer de 20 años con un tumor del estroma gonadal específico del ovario, variedad tumor de los cordones sexuales, con túbulos…”
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