Search Results - "Bram, R J"

Gut T cell-independent IgA responses to commensal bacteria require engagement of the TACI receptor on B cells by Grasset, E K, Chorny, A, Casas-Recasens, S, Gutzeit, C, Bongers, G, Thomsen, I, Chen, L, He, Z, Matthews, D B, Oropallo, M A, Veeramreddy, P, Uzzan, M, Mortha, A, Carrillo, J, Reis, B S, Ramanujam, M, Sintes, J, Magri, G, Maglione, P J, Cunningham-Rundles, C, Bram, R J, Faith, J, Mehandru, S, Pabst, O, Cerutti, A

“…The gut mounts secretory immunoglobulin A (SIgA) responses to commensal bacteria through nonredundant T cell-dependent (TD) and T cell-independent (TI)…”
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NF-AT Activation Induced by a CAML-Interacting Member of the Tumor Necrosis Factor Receptor Superfamily by von Bülow, Götz-Ulrich, Bram, Richard J.

“…Activation of the nuclear factor of activated T cells transcription factor (NF-AT) is a key event underlying lymphocyte action. The CAML (calcium-modulator and…”
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Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location by BRAM, R. J, HUNG, D. T, MARTIN, P. K, SCHREIBER, S. L, CRABTREE, G. R

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Calcium signalling in T cells stimulated by a cyclophilin B-binding protein by Bram, Richard J, Crabtreet, Gerald R

“…The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound…”
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BCMA is essential for the survival of long-lived bone marrow plasma cells by O'Connor, Brian P, Raman, Vanitha S, Erickson, Loren D, Cook, W James, Weaver, Lehn K, Ahonen, Cory, Lin, Ling-Li, Mantchev, George T, Bram, Richard J, Noelle, Randolph J

“…Long-lived humoral immunity is manifested by the ability of bone marrow plasma cells (PCs) to survive for extended periods of time. Recent studies have…”
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Co-localization of Calcium-modulating Cyclophilin Ligand with Intracellular Calcium Pools by Holloway, M P, Bram, R J

“…The calcium-modulating cyclophilin ligand (CAML) protein activates Ca 2+ influx signaling when overexpressed in Jurkat T cells. Although CAML appears to…”
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Regulation of the T-Independent Humoral Response by TACI by von Bülow, Götz-Ulrich, van Deursen, Jan M, Bram, Richard J

“…TACI is a TNFR homolog expressed by mature B lymphocytes that has been implicated in the positive regulation of B cell growth and antibody production, as well…”
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Isolation of a Saccharomyces cerevisiae centromere DNA-binding protein, its human homolog, and its possible role as a transcription factor by BRAM, R. J, KORNBERG, R. D

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Specific Protein Binding to Far Upstream Activating Sequences in Polymerase II Promoters by Bram, Richard J., Kornberg, Roger D.

“…A binding activity specific for the upstream activating sequence of the GAL1-GAL10 promoter of Saccharomyces cerevisiae has been purified 220-fold on the basis…”
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CAML regulates Bim-dependent thymocyte death by Edgar, C E, Lindquist, L D, McKean, D L, Strasser, A, Bram, R J

“…Appropriate control of apoptosis during T lymphocyte differentiation is critical for destruction of T cells bearing potentially autoreactive or useless…”
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Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A by Flanagan, W. Michael, Corthésy, Blaise, Bram, Richard J, Crabtree, Gerald R

“…Cyclosporin A and FK506 inhibit T- and B-cell activation and other processes essential to an effective immune response. In T lymphocytes these drugs disrupt an…”
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A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcription by Bram, R.J., Lue, N.F., Kornberg, R.D.

“…Binding sites for the GAL4‐positive regulatory protein have been identified upstream of six galactose‐inducible genes of Saccharomyces cerevisiae on the basis…”
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Kaposi's Sarcoma-Associated Herpesvirus Mitochondrial K7 Protein Targets a Cellular Calcium-Modulating Cyclophilin Ligand To Modulate Intracellular Calcium Concentration and Inhibit Apoptosis by Feng, Pinghui, Park, Junsoo, Lee, Bok-Soo, Lee, Sun-Hwa, Bram, Richard J, Jung, Jae U

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CAML Is Required for Efficient EGF Receptor Recycling by Tran, David D, Russell, Helen R, Sutor, Shari L, van Deursen, Jan, Bram, Richard J

“…Calcium-modulating cyclophilin ligand (CAML) is a ubiquitous protein that has been implicated in signaling from the cell surface receptor TACI in lymphocytes,…”
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A hydrophobic domain of Ca2+-modulating cyclophilin ligand modulates calcium influx signaling in T lymphocytes by Holloway, M P, Bram, R J

“…Ca2+-modulating cyclophilin ligand (CAML) was originally described as a cyclophilin B-binding protein whose overexpression in T cells causes a rise in…”
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Molecular cloning and functional characterization of murine Transmembrane Activator and CAML Interactor (TACI) with chromosomal localization in human and mouse by von Bülow, Götz-Ulrich, Russell, Helen, Copeland, Neal G, Gilbert, Debra J, Jenkins, Nancy A, Bram, Richard J

“…The human Taci gene (Transmembrane Activator and CAML Interactor) encodes a recently discovered member of the Tumor Necrosis Factor Receptor family. TACI is…”
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Isolation of mutant T lymphocytes with defects in capacitative calcium entry by Serafini, Andrew T., Lewis, Richard S., Clipstone, Neil A., Bram, Richard J., Fanger, Christopher, Flering, Steve, Herzenberg, Leonard A., Crabtree, Gerald R.

“…Calcium and calcium-binding proteins play important roles in the signaling cascade leading from the initial engagement of TCRs on T cells to the fully…”
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Calcium-Modulating Cyclophilin Ligand Desensitizes Hormone-Evoked Calcium Release by Tovey, Stephen C., Bootman, Martin D., Lipp, Peter, Berridge, Michael J., Bram, Richard J.

“…The Ca2+-modulating cyclophilin ligand (CAML) protein causes stimulation of transcription factors via activation of a store-operated Ca2+ entry pathway. Since…”
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Isolation of a cDNA encoding the chicken homologue of the human calcium-modulating cyclophilin ligand by Bram, Richard J

“…In order to identify important regions of the human CAML (calcium-modulating cyclophilin ligand) protein, a cDNA encoding the chicken homologue was isolated…”
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Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL by Kanswal, S., Katsenelson, N., Selvapandiyan, A., Bram, R. J., Akkoyunlu, M.

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