Search Results - "Braks, Joanna A.M."

Regulation of Sexual Development of Plasmodium by Translational Repression by Mair, Gunnar R, Braks, Joanna A.M, Garver, Lindsey S, Wiegant, Joop C.A.G, Hall, Neil, Dirks, Roeland W, Khan, Shahid M, Dimopoulos, George, Janse, Chris J, Waters, Andrew P

“…Translational repression of messenger RNAs (mRNAs) plays an important role in sexual differentiation and gametogenesis in multicellular eukaryotes…”
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Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole by Fougère, Aurélie, Jackson, Andrew P, Bechtsi, Dafni Paraskevi, Braks, Joanna A M, Annoura, Takeshi, Fonager, Jannik, Spaccapelo, Roberta, Ramesar, Jai, Chevalley-Maurel, Séverine, Klop, Onny, van der Laan, Annelies M A, Tanke, Hans J, Kocken, Clemens H M, Pasini, Erica M, Khan, Shahid M, Böhme, Ulrike, van Ooij, Christiaan, Otto, Thomas D, Janse, Chris J, Franke-Fayard, Blandine

“…Many variant proteins encoded by Plasmodium-specific multigene families are exported into red blood cells (RBC). P. falciparum-specific variant proteins…”
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Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo by Fonager, Jannik, Pasini, Erica M, Braks, Joanna A M, Klop, Onny, Ramesar, Jai, Remarque, Edmond J, Vroegrijk, Irene O C M, van Duinen, Sjoerd G, Thomas, Alan W, Khan, Shahid M, Mann, Matthias, Kocken, Clemens H M, Janse, Chris J, Franke-Fayard, Blandine M D

“…Adherence of parasite-infected red blood cells (irbc) to the vascular endothelium of organs plays a key role in the pathogenesis of Plasmodium falciparum…”
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Negative selection using yeast cytosine deaminase/uracil phosphoribosyl transferase in Plasmodium falciparum for targeted gene deletion by double crossover recombination by Maier, Alexander G., Braks, Joanna A.M., Waters, Andrew P., Cowman, Alan F.

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conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes by Braks, Joanna A.M, Mair, Gunnar R, Franke-Fayard, Blandine, Janse, Chris J, Waters, Andrew P

“…Translational repression (TR) plays an important role in post-transcriptional regulation of gene expression and embryonic development in metazoans. TR also…”
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Hyperbaric oxygen therapy as a prevention modality for radiation damage in the mandibles of mice by Spiegelberg, Linda, Braks, Joanna A.M, Groeneveldt, Lisanne C, Djasim, Urville M, van der Wal, Karel G.H, Wolvius, Eppo B

“…Abstract Background Radiation therapy (RT) as part head and neck cancer treatment often leads to irradiation of surrounding normal tissue, such as mandibular…”
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Structure and expression of Xenopus prohormone convertase PC2 by Braks, Joanna A.M., Guldemond, Karin C.W., van Riel, Maarten C.H.M., Coenen, Anton J.M., Martens, Gerard J.M.

“…The multifunctional prohormone, proopiomelanocortin (POMC), is processed in the melanotrope cells of the pituitary pars intermedia at pairs of basic amino acid…”
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Translational control of UIS4 protein of the host-parasite interface is mediated by the RNA binding protein Puf2 in Plasmodium berghei sporozoites by Silva, Patrícia A. G. C., dos Santos Guerreiro, Ana Maria, Santos, Jorge, Braks, Joanna A. M., Janse, Chris J., Mair, Gunnar

“…Copyright: © 2016 Silva et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits…”
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A Central Role for P48/45 in Malaria Parasite Male Gamete Fertility by van Dijk, Melissa R., Janse, Chris J., Thompson, Joanne, Waters, Andrew P., Braks, Joanna A.M., Dodemont, Huub J., Stunnenberg, Henk G., van Gemert, Geert-Jan, Sauerwein, Robert W., Eling, Wijnand

“…Fertilization and zygote development are obligate features of the malaria parasite life cycle and occur during parasite transmission to mosquitoes. The surface…”
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Optical Imaging of Tumor Response to Hyperbaric Oxygen Treatment and Irradiation in an Orthotopic Mouse Model of Head and Neck Squamous Cell Carcinoma by Braks, Joanna A. M., Spiegelberg, Linda, Koljenovic, Senada, Ridwan, Yanto, Keereweer, Stijn, Kanaar, Roland, Wolvius, Eppo B., Essers, Jeroen

“…Purpose Hyperbaric oxygen therapy (HBOT) is used in the treatment of radiation-induced tissue injury but its effect on (residual) tumor tissue is indistinct…”
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Gene expression analysis reveals inhibition of radiation-induced TGFβ-signaling by hyperbaric oxygen therapy in mouse salivary glands by Spiegelberg, Linda, Swagemakers, Sigrid M A, Van Ijcken, Wilfred F J, Oole, Edwin, Wolvius, Eppo B, Essers, Jeroen, Braks, Joanna A M

“…A side effect of radiation therapy in the head and neck region is injury to surrounding healthy tissues such as irreversible impaired function of the salivary…”
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Development and application of a positive–negative selectable marker system for use in reverse genetics in Plasmodium by Braks, Joanna A. M., Franke-Fayard, Blandine, Kroeze, Hans, Janse, Chris J., Waters, Andrew P.

“…A limitation of transfection of malaria parasites is the availability of only a low number of positive selectable markers for selection of transformed mutants…”
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7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway by Braks, J A, Martens, G J

“…The neuroendocrine polypeptide 7B2 is a highly conserved secretory protein selectively present in prohormone-producing cells equipped with a regulated…”
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The Neuroendocrine Polypeptide 7B2 is an Endogenous Inhibitor of Prohormone Convertase PC2 by Gerard J. M. Martens, Joanna A. M. Braks, Eib, Douglas W., Zhou, Yi, Lindberg, Iris

“…The subtilisin-like prohormone convertase PC2 and the polypeptide 7B2 (an intracellularly cleaved protein of unknown function) are both selectively present in…”
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The neuroendocrine chaperone 7B2 can enhance in vitro POMC cleavage by prohormone convertase PC2 by Braks, Joanna A.M., Martens, Gerard J.M.

“…We previously showed that the neuroendocrine polypeptide 7B2 transiently interacts with prohormone convertase PC2 in the secretory pathway of neuroendocrine…”
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Dissociation of the Complex between the Neuroendocrine Chaperone 7B2 and Prohormone Convertase PC2 is not Associated with proPC2 Maturation by Braks, Joanna A. M., Horssen, A. Martin, Martens, Gerard J. M.

“…7B2 is a highly conserved neuroendocrine protein that is associated with the proform of the prohormone convertase PC2 in the early stages of the secretory…”
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