Search Results - "Brakkee, Jan H."

Melanocortin Receptor 4 Deficiency Affects Body Weight Regulation, Grooming Behavior, and Substrate Preference in the Rat by Mul, Joram D., Boxtel, Ruben, Bergen, Dylan J.M., Brans, Maike A.D., Brakkee, Jan H., Toonen, Pim W., Garner, Keith M., Adan, Roger A.H., Cuppen, Edwin

“…Obesity is caused by an imbalance between energy intake and expenditure and has become a major health‐care problem in western society. The central melanocortin…”
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Wireless implantable micro-stimulation device for high frequency bilateral deep brain stimulation in freely moving mice by de Haas, Ria, Struikmans, Rolf, van der Plasse, Geoffrey, van Kerkhof, Linda, Brakkee, Jan H., Kas, Martien J.H., Westenberg, Herman G.M.

“…► This paper describes a new light-weight wireless implantable micro stimulator device for mice. ► The device delivers biphasic pulse patterns to two…”
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Sciatic nerve regeneration in mice and rats: recovery of sensory innervation is followed by a slowly retreating neuropathic pain-like syndrome by Vogelaar, Christina F., Vrinten, Dorien H., Hoekman, Marco F.M., Brakkee, Jan H., Burbach, J. Peter H., Hamers, Frank P.T.

“…Peripheral nerve regeneration has been studied extensively in the sciatic nerve crush model, at the level of both function and gene expression. The crush…”
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Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat by Adan, Roger A.H, Szklarczyk, Arkadiusz W, Oosterom, Julia, Brakkee, Jan H, Nijenhuis, Wouter A.J, Schaaper, Wim M.M, Meloen, Rob H, Gispen, Willem Hendrik

“…Since the melanocortin MC 3 and melanocortin MC 4 receptors are the main melanocortin receptor subtypes expressed in rat brain, we characterized the activity…”
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Melanocortin MC4 receptor-mediated feeding and grooming in rodents by Mul, Joram D., Spruijt, Berry M., Brakkee, Jan H., Adan, Roger A.H.

“…Decades ago it was recognized that the pharmacological profile of melanocortin ligands that stimulated grooming behavior in rats was strikingly similar to that…”
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Voluntary access to a warm plate reduces hyperactivity in activity-based anorexia by Hillebrand, Jacquelien J.G., de Rijke, Corine E., Brakkee, Jan H., Kas, Martien J.H., Adan, Roger A.H.

“…Activity-based anorexia (ABA) is considered an animal model of anorexia nervosa. In ABA, scheduled feeding in combination with voluntary wheel running leads to…”
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Evaluation of temperature rise and bonding strength in cements used for permanent head attachments in rats and mice by Agterberg, Martijn J.H, Spoelstra, Edwin N, Wijst, Suzanne van der, Brakkee, Jan H, Wiegant, Victor M, Hamelink, Ralph, Brouns, Kim, Westerink, Ben H, Remie, Rene

“…In animal models, devices such as indwelling catheters and intracranial cannulae are often fixed on the skull to allow sampling or injection in the freely…”
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Exercise training improves functional recovery and motor nerve conduction velocity after sciatic nerve crush lesion in the rat by van Meeteren, N L, Brakkee, J H, Hamers, F P, Helders, P J, Gispen, W H

“…To observe the effects of exercise training on recuperation of sensorimotor function in the early phase of regeneration, and to monitor the long-term effects…”
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The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat by Ter Laak, Mariël P, Brakkee, Jan H, Adan, Roger A.H, Hamers, Frank P.T, Gispen, Willem Hendrik

“…The neurotrophic and neuroprotective potential of the α-melanocyte-stimulating hormone (α-MSH) analog cyclo-[Ac-Nle 4,Asp 5, d-Phe 7,Lys 10]α-MSH-(4–10) amide…”
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Reduced glutathione protects against cisplatin-induced neurotoxicity in rats by HAMERS, F. P. T, BRAKKEE, J. H, CAVALLETTI, E, TEDESCHI, M, MARMONTI, L, PEZZONI, G, NEIJT, J. P, GISPEN, W. H

“…Reduced glutathione (GSH) is reported to diminish cisplatin-induced neurotoxicity, and it was for this reason that we studied GSH in an animal model of…”
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Expression of melanocortin receptors and pro-opiomelanocortin in the rat spinal cord in relation to neurotrophic effects of melanocortins by van der Kraan, Manou, Tatro, Jeffrey B., Entwistle, Margaret L., Brakkee, Jan H., Burbach, J.Peter H., Adan, Roger A.H., Gispen, Willem Hendrik

“…Although neurotrophic effects of α-melanocyte-stimulating hormone (α-MSH) are well established, the mechanism underlying these effects is unknown. To identify…”
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Melanocortin MC(4) receptor-mediated feeding and grooming in rodents by Mul, Joram D, Spruijt, Berry M, Brakkee, Jan H, Adan, Roger A H

“…Decades ago it was recognized that the pharmacological profile of melanocortin ligands that stimulated grooming behavior in rats was strikingly similar to that…”
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The effect of exercise training on functional recovery after sciatic nerve crush in the rat by van Meeteren, N L, Brakkee, J H, Helders, P J, Gispen, W H

“…Two separate experiments were carried out in order to evaluate the influence of moderate swim training and treadmill running on the rate of recovery of…”
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Methods for producing a reproducible crush in the sciatic and tibial nerve of the rat and rapid and precise testing of return of sensory function. Beneficial effects of melanocortins by De Koning, P, Brakkee, J H, Gispen, W H

“…A procedure for placing a crush lesion in the sciatic and tibial nerve of the rat based on anatomical landmarks is described. These crush lesions are used to…”
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Functional recovery from sciatic nerve crush lesion in the rat correlates with individual differences in responses to chronic intermittent stress by van Meeteren, Nico L.U., Brakkee, Jan H., Helders, Paul J.M., Wiegant, Victor M., Gispen, Willem H.

“…The aim of the present study was to monitor the influence of chronic stress on functional recovery from a sciatic nerve crush lesion in the rat. Male Wistar…”
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Putative neurotrophic factors and functional recovery from peripheral nerve damage in the rat by Zee, Catharina E.E.M., Brakkee, Jan H., Gispen, Willem Hendrik

“…1 In rats, recovery of sensory‐motor function following a crush lesion of the sciatic or tibial nerve was monitored by measuring foot reflex withdrawal from a…”
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Nasal administration of an ACTH(4–9) peptide analogue with dimethyl‐β‐cyclodextrin as an absorption enhancer: pharmacokinetics and dynamics by Schipper, Nicolaas G.M., Verhoef, J. Coos, Lannoy, Larissa M., Romeijn, Stefan G., Brakkee, Jan H., Wiegant, Victor M., Gispen, Willem Hendrik, Merkus, Frans W.H.M.

“…1 The systemic absorption and the neurotrophic effect of the metabolically stabilized ACTH (4–9) analogue, Org2766, were investigated following intranasal…”
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alpha-MSH and Org.2766 in peripheral nerve regeneration: different routes of delivery by Van der Zee, C E, Brakkee, J H, Gispen, W H

“…The efficacy of melanocortins (alpha-MSH and an ACTH-(4-9) analog, Org.2766) in accelerating functional recovery from sciatic nerve damage following various…”
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Spontaneous bodily rotations and direction of locomotion at different times after radio frequency lesions at sites in and near the substantia nigra by Isaacson, R L, Danks, A M, Oestreicher, A B, Brakkee, J H, Gispen, W H

“…Rats were prepared with radio frequency lesions of the dorsolateral or ventromedial regions of the substantia nigra. Other rats were prepared as operated and…”
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The time course of excessive grooming after neuropeptide administration by Isaacson, R L, Hannigan, Jr, J H, Brakkee, J H, Gispen, W H

“…In this paper we review the temporal pattern of excessive grooming in the hour or so following the central injection of ACTH1-24 in the rat. Changes in the…”
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