Search Results - "Brakenhoff, J.P.G"
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1
Pharmacokinetic profile of a modified release formulation of trimetazidine (TMZ MR 35 mg) in the elderly and patients with renal failure
Published in Biopharmaceutics & drug disposition (01-05-2003)“…Objectives – To study the effect of age and renal function on the pharmacokinetic profile of a modified release tablet of trimetazidine (TMZ MR 35 mg)…”
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2
Toxicity of fotemustine in rat hepatocytes and mechanism-based protection against it
Published in Chemico-biological interactions (03-04-1998)“…Fotemustine is a relatively novel DNA-alkylating 2-chloroethyl-substituted N-nitrosourea (CENU) drug, clinically used for the treatment of disseminated…”
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Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms
Published in Biochemical pharmacology (01-12-1988)“…The biotransformation and the hepato- and nephrotoxicity of the mercapturic acids (N-acetyl-1-cysteine S-conjugates) of three structurally related…”
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4
High-throughput solid-phase extraction for the determination of cimetidine in human plasma
Published in Journal of chromatography. B, Biomedical sciences and applications (04-09-1998)“…For the implementation and validation of an automated `high-throughput' solid-phase extraction (SPE) system, using microtiter solid-phase technology and a…”
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